In today’s digital age, there is a growing expectation that digital technologies should help address social and environmental challenges, such as climate change. In response, digital infrastructural platforms increasingly employ gamification as a communication strategy to promote behaviors aligned with the public good. However, when implemented within commercial platforms, such initiatives often s

Importance: Better understanding of patients' attitudes toward deprescribing specific medications will inform future deprescribing interventions. Objective: To investigate older adults' attitudes toward deprescribing by investigating which medications they would like to have deprescribed, the reasons why, and patient factors associated with interest in deprescribing. Design, Setting, and Participa

External quality assessment (EQA) schemes for pathology are essential, yet large/international programmes do not assess morphology-based biomarkers or address local/regional needs. This study outlines bottom-up initiated, flexible Swedish Digital Pathology EQA rounds for breast pathology, and presents results from the 2021 and 2023 rounds. Six breast carcinoma cases were selected for each EQA roun

Background: Adverse skin reactions to continuous glucose monitors (CGMs) and devices for continuous subcutaneous insulin infusions (CSIIs) (“diabetes medical devices” (MDs)) are well known. However, epidemiological studies on prevalence and skin rash details are lacking. The objective of this study was to describe the prevalence and details of skin rash to diabetes MDs in adults with type 1 diabet

We report three cases of contact allergy to a mislabelled hair dye product. A hair dye product labelled as p-phenylenediamine-free has been found to contain p-phenylenediamine by a chemical analysis at the level above the limits allowed in the product.

Current trends aim at improving the surface integrity of aerospace Ni-based superalloys by reducing the temperature rise in the cutting zone in order to minimize tool wear, as well as reducing the thermally induced tensile residual stresses on the machined surface. The manufacturing industry is also driven by developing high performance sustainable machining processes. Cryogenic machining (CM) usi

The emergence of cyber mistreatment among frontline workers in their digital interactions with customers, clients and patients represents a significant but relatively new work environment risk within the service sector. Human resource management has a key role in digital transformation, which includes securing safe and healthy workplaces and fostering sustainable practices for handling cyber mistr

Glycolipid-lectin-driven endocytosis controls the formation of clathrin-independent carriers and the internalization of various cargos such as β1 integrin. Whether this process is regulated in a dynamic manner remained unexplored. Here we demonstrate that, within minutes, the epidermal growth factor triggers the galectin-driven endocytosis of cell-surface glycoproteins, such as integrins, that are

In this paper, we present a summary of fractal calculus and propose the use of Lagrange multipliers for both fractal calculus and fractal variational calculus with constraints. We examine the application of these methods across various branches of physics. By employing fractal variational calculus with constraints, we derive fundamental equations such as the fractal mechanical wave equation, the f

Seminar Date: 2025-06-02 Course: BUSN79, Degree Project in Accounting and Finance Supervisor & Examiner: Diem Nguyen & Reda Moursli Authors: Märta Eklöf & Ebba Svensson Five Key Words: M&A Deal Premium, Aggregate Funding Conditions, Target Operational Performance, Financial Constraints, Bargaining Power Purpose: The purpose of this study is to test whether aggregate funding co

The acute respiratory distress syndrome (ARDS) inflammatory environment alters mesenchymal stromal cell (MSC) gene and protein expression but effects on microRNA (miRNA) content of MSC-extracellular vesicle (EVs) remain unknown. To assess this, sequencing analysis of EV-miRNAs prepared from human bone marrow-derived MSCs (hMSCs) exposed ex vivo to bronchoalveolar lavage fluid (BALF) from ARDS pati

Developing an efficient code for large, multiscale astrophysical simulations is crucial in preparing for the upcoming era of exascale computing. RAMSES is an astrophysical simulation code that employs parallel processing based on the message-passing interface (MPI). However, it has limitations in computational and memory efficiency when using a large number of CPU cores. The problem stems from ine

In modern security systems, the widespread deployment of battery-powered IoT devices creates a critical need for accurate battery replacement strategies. Premature replacement leads to unnecessary waste, while delayed replacement risks system failure in the case of an incident. This thesis presents the workflow building on limited knowledge of the data in an unsupervised learning setting to a work

Purpose: Myocardial infarctions (MIs) can occur in underlying obstructive coronary artery disease (MI-CAD) or in non-obstructive coronary arteries (MINOCA). The primary objectives of the study were to investigate the prevalence of MI-CAD and MINOCA in people with CAL, and to explore if CAL is an independent risk factor for MI-CAD and MINOCA. Secondary objectives were to explore these research ques

Background: The growing challenges of population aging create a pressing need for specialized geriatric medicine services to effectively address the complex health needs of older adults and influence supportive healthcare policies. Older patients may present clinical complexity with multimorbidity, disability, and/or frailty, necessitating a shift from the traditional organ-oriented clinical appro

Summary: Screening initiatives for osteoporosis must facilitate treatment of those at elevated fracture risk. In a randomized controlled trial of 24,229 women, those in the screening group with FRAX ≥ 15% were invited for DXA with AOM treatment offered as per national guidelines. Treatment initiation in the following year was 9.5 times higher compared with controls. Purpose: To determine if screen

This thesis presents a topology optimization framework for anisotropic elastoplastic structures based on the deformation theory of plasticity. Traditional methods often assume linear elasticity and isotropic material behavior, which limits their ability to model real-world materials that exhibit anisotropy and undergo plastic deformation. Although incremental elastoplastic models can accurately ca