We sought to quantify the morphology in vivo of hippocampi in patients with drug resistant temporal lobe epilepsy (TLE) via magnetic resonance imaging (MRI), prior to temporal lobe resection, and the correlation of surface-based shape analysis of morphology and clinical cognitive function.Thirty patients with drug-resistant TLE and twenty healthy controls underwent clinical neuropsychological test

BACKGROUND: Global inequalities in access to health care are reflected in differences in cancer survival. The CONCORD programme was designed to assess worldwide differences and trends in population-based cancer survival. In this population-based study, we aimed to estimate survival inequalities globally for several subtypes of childhood leukaemia.METHODS: Cancer registries participating in CONCORD

The astrological doctrines of aspects and planetary dignities found in the authoritative texts of the Tājika (Sanskritized Perso-Arabic) school are examined with respect to their origins and historical development, with particular emphasis on Balabhadra’s encyclopaedic Hāyanaratna (1649) and its quotations from the perhaps earliest work of the school, Samarasiṃha’s Tājikaśāstra (thirteenth century

This paper supplements and corrects the information given in the works of David Pingree regarding four major authors on Tājika or Sanskritized Perso-Arabic astrology from the fourteenth to the seventeenth century: Tejaḥsiṃha, Yādavasūri, Bālakṛṣṇa and Balabhadra. It further contributes information on a fifth such author, Tuka, not discussed by Pingree.

The highly popular Praśnatantra attributed to Nīlakaṇṭha of Kāśī (fl. late 16th century) and sometimes regarded as the third volume of his Tājikanīlakaṇṭhī is shown to depend for its basic structure on an abridged Sanskrit version of the Kitāb fi l-masāʾil wa-l-aḥkām by Sahl ibn Bishr (early 9th century), apparently authored by Samarasiṃha in the 13th century, to which quotations primarily from Sa

Poem framfört vid doktorspromotionen i Lund 24 maj 2019

Serine hydroxymethyltransferase (SHMT) is the major source of 1-carbon units required for nucleotide synthesis. Humans have cytosolic (SHMT1) and mitochondrial (SHMT2) isoforms, which are upregulated in numerous cancers, making the enzyme an attractive drug target. Here, we show that the antifolates lometrexol and pemetrexed are inhibitors of SHMT2 and solve the first SHMT2-antifolate structures.

Beslutsfattare bör inse betydelsen av butikers vara eller inte vara för samhällets utveckling innan det är för sent, skriver Karin M Ekström, professor i företagsekonomi, och Håkan Jönsson, docent i etnologi.

Occupational well-being is a central issue underpinning factors that constitute a good life. This study aimed to explore occupational well-being among Middle Eastern immigrants to Sweden, as reflected in the occupations performed in the context of psychosocial health care. Ten participants experiencing mental health issues, who received occupation-based rehabilitation, were interviewed. Grounded t

There is a scarcity of rehabilitation methods for people with stress-related disorders that are effective in terms of return to work and reducing sick leave. This chapter describes the Redesigning Daily Occupations (ReDOTM) program for women with stress-related disorders, the development, its main principles, and primary and secondary outcomes. The ReDOTM program, which addresses people’s whole re

Due to the great variation in approaches to psychiatric rehabilitation, the literature does not provide a uniform description of these methods. In this review, outcomes in terms of subjective quality of life are discussed in relation to vocational training, activity-based rehabilitation, case management, and social skills training. Relationships between aspects of daily life and subjective quality