BibA, a group B streptococcus (GBS) surface protein, has been shown to protect the pathogen from phagocytic killing by sequestering a complement inhibitor: C4b-binding protein (C4BP). Here, the X-ray crystallographic structure of a GBS BibA fragment (BibA126-398) and a low-resolution small-angle X-ray scattering (SAXS) structure of the full-length N-terminal domain (BibA34-400) are described. The

We present the first application of a new approach, proposed in (2016 J. Phys. G: Nucl. Part. Phys. 43 04LT01) to derive coupling constants of the Skyrme energy density functional (EDF) from ab initio Hamiltonian. By perturbing the ab initio Hamiltonian with several functional generators defining the Skyrme EDF, we create a set of metadata that is then used to constrain the coupling constants of t

Serum vitamin D deficiency is widespread among older adults and is a potential modifiable risk factor for frailty. Moreover, frailty has been suggested as an intermediate step in the association between low levels of vitamin D and mortality. Hence, we conducted a systematic review of the literature and meta-analysis to test the possible association of low concentrations of serum 25-hydroxyvitamin

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Denna bok ger en integrerad framställning av de mestadels sakrättsliga aspekter som aktualiseras vid kreditgivning och finansiering, med särskilt fokus på realsäkerhetsfrågor.Boken inleds med en koncis översikt av ämnet sakrätt. Därefter följer presentationer av ägarförbehåll (återtagandeförbehåll) som kreditsäkerhet, olika slag av panträtt i lös egendom, fastighetspant och lagstiftningen om föret

Med projektet Ordbro sätter Centrum för Öresundsstudier fokus på och undersöker språk och språkkultur i det svenska och danska språket. Vi ber personer med olika bakgrund, inriktning och modersmål att utveckla hur de ser på ett visst danskt eller svenskt ord, begrepp eller talesätt.

Om vikten av att se till helheten när man jämför. Patrik Lindskoug, docent i civilrätt reflekterar över skillnader och likheter inom affärsjuridiken och samhällsstrukturer i Norden.

The hypothalamus is the central regulator of energy homeostasis. Hypothalamic neuronal circuits are disrupted upon overfeeding, and play a role in the development of metabolic disorders. While mouse models have been extensively employed for understanding the mechanisms of hypothalamic dysfunction, functional magnetic resonance imaging (fMRI) on hypothalamic nuclei has been challenging. We implemen

Background: Dietary advice remains the cornerstone of prevention and management of type 2 diabetes (T2D). However, understanding the efficacy of dietary interventions is confounded by the challenges inherent in assessing free living diet. Here we profiled dietary metabolites to investigate glycaemic deterioration and cardiometabolic risk in people at risk of or living with T2D. Methods: We analyse

Seating of churches is crucial to how the building is used, experienced and structured. The liturgical practice and contemporary use of seating of chairs play a fundamental part for the participatory performance on a liturgical stage. The long tradition of close interaction between church and nation, society and contemporary material culture, plays part in shaping the design process of the physicaSeating of churches is crucial to how the building is used, experienced and structured. The liturgical practice and contemporary use of seating of chairs play a fundamental part for the participatory performance on a liturgical stage. The long tradition of close interaction between church and nation, society and Contemporary material culture, plays part in shaping the design process of the physica

This paper presents the measurements of π±, K ±, p and p ¯ transverse momentum (pT) spectra as a function of charged-particle multiplicity density in proton–proton (pp) collisions at s=13TeV with the ALICE detector at the LHC. Such study allows us to isolate the center-of-mass energy dependence of light-flavour particle production. The measurements reported here cover a pT range from 0.1 to 20 GeV

BACKGROUND: Pre-hospital circumstances, cardiac arrest characteristics, comorbidities and clinical status on admission are strongly associated with outcome after out-of-hospital cardiac arrest (OHCA). Early prediction of outcome may inform prognosis, tailor therapy and help in interpreting the intervention effect in heterogenous clinical trials. This study aimed to create a model for early predict