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Expansion and fluctuations-enhanced microscopy for nanoscale molecular profiling of cells and tissues

Advances in super-resolution microscopy enable the molecular profiling of cells and tissues at the nanoscale level, surpassing the diffraction limit of conventional light microscopy. However, super-resolution techniques typically require access to expensive specialized equipment and extensive training, limiting their broad applicability. Here we provide a detailed protocol for combining expansion

Rediscovering nitroxoline : a metal-chelating agent bridging infection and cancer

Nitroxoline, a legacy antimicrobial agent, is gaining attention for its potential repurposing in infectious diseases and oncology. Its broad-spectrum activity, including biofilm disruption and metal-chelating properties, supports diverse therapeutic applications. However, its systemic use is limited by rapid urinary excretion, short plasma half-life, and limited tissue distribution. In this review

Digital platforms for circular shopping: slowing down and speeding up second-hand clothing consumption

This paper aims to empirically explore and conceptualise how circular fashion platforms enable and shape the practice of secondhand clothes shopping. Taking a shopping-as-practice approach and drawing on an ethnographically inspired study, this paper explores how a Swedish digital second-hand commerce platform enables different modes of shopping. The analysis shows that this platform and its socio

Ethnicity of Scandinavian populations from 1050-1500 A.D.

In a skeletal material of five individuals from a non-christian cemetery in Middle Sweden (Vivallen) non-metric traits in skulls and mandibles were studied. Burial gifts and burial customs indicate Saamisch/Lappish origin of these individuals. Their affinities are explored here by comparing the traits with data on crania of Saamish populations from Northern Norway as well a with data of Nordic pop

South Korea’s democracy in the shadow of the far-right

Former president Yoon Suk-yeol’s martial law attempt, impeachment and the June 2025 presidential election exposed South Korea’s rising far-right — rooted in economic inequality, generational and gender divides and religious nationalism. Liberal candidate Lee Jae-myung won the election, but far-right forces remain potent. The Lee administration and South Korean citizens now must navigate domestic p

The Business of Being You: How Social Media Influencers Manage Stakeholder Relationships for Long-Term Success

In the evolving landscape of digital entrepreneurship, social media influencers (SMIs) have emerged as strategic actors navigating complex stakeholder environments to sustain long-term business viability. While existing literature extensively addresses branding, authenticity, and audience engagement, it often overlooks the strategic coordination required to manage stakeholder relationships across

Role of Amide Proton Transfer Weighted MRI in Predicting MGMTp Methylation Status, p53-Status, Ki-67 Index, IDH-Status, and ATRX Expression in WHO Grade 4 High Grade Glioma

Objectives: To assess amide proton transfer weighted (APTw) MR imaging capabilities in differentiating high-grade glial tumors across alpha-thalassemia/mental retardation X-linked (ATRX) expression, tumor-suppressor protein p53 expression (p53), O6-methylguanine-DNA methyltransferase promoter (MGMTp) methylation, isocitrate dehydrogenase (IDH) status, and proliferation marker Ki-67 (Ki-67 index)

Why Constitutional Monarchy Is the Best Path Forward for Iran

Constitutional monarchy offers Iran a politically stable and culturally resonant alternative to partisan republicanism. Grounded in both empirical research and philosophical tradition, it combines symbolic authority with institutional continuity, enabling national unity without authoritarianism. Monarchs function as neutral anchors above political conflict, often at lower public cost and with grea

T cell responses towards PINK1 and α-synuclein are elevated in prodromal Parkinson’s disease

A role of the immune system in Parkinson’s disease (PD) progression has long been suspected due to the increased frequency of activated glial cells and infiltrating T cells in the substantia nigra. It was previously reported that PD donors have increased T cell responses towards PINK1 and α-synuclein (α-syn), two Lewy body-associated proteins. Further, T cell reactivity towards α-syn was highest c

Proximal venous ultrasound with risk stratification safely excludes deep venous thrombosis in emergency department routine care : an observational study

Background: Lower limb deep vein thrombosis (DVT) is common in emergency departments (EDs) and can be fatal if left untreated due to the risk of progression to pulmonary embolism (PE). In Scandinavia, DVT diagnosis typically relies on ultrasound performed outside the ED in the diagnostic departments. However, international guidelines now recommend combining limited/proximal compression ultrasound

A scoping review of remote and unsupervised digital cognitive assessments in preclinical Alzheimer’s disease

Characterizing subtle cognitive changes in preclinical Alzheimer’s disease (AD) is difficult using traditional neuropsychological assessments. Remote and unsupervised digital assessments can improve scalability, measurement reliability, and ecological validity, enabling the capture of subtle changes. We evaluate such tools for use in preclinical AD, or cognitively unimpaired individuals with abnor