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ERC grant for research on diabetes

Professor Charlotte Ling at Lund University Diabetes Centre (LUDC) has been awarded a Proof of Concept Grant by the European Research Council, ERC, for the further development of her successful research on epigenetic biomarkers. The innovation-driven research project will investigate biomarkers for predicting who benefits from metformin in the treatment of type 2 diabetes. In her research, Charlot

https://www.ludc.lu.se/article/erc-grant-research-diabetes - 2025-11-19

Diabetes researcher Tove Fall is the recipient of the Leif C. Groop award 2023

Tove Fall became a familiar face during the Covid-19 pandemic when she was often seen in Swedish media talking about the spread and progression of the disease in Sweden. She is also an outstanding diabetes researcher who uses large quantities of data to gain a better understanding of the development of diabetes. Tove Fall is now awarded the Leif C. Groop award for outstanding diabetes research for

https://www.ludc.lu.se/article/diabetes-researcher-tove-fall-recipient-leif-c-groop-award-2023 - 2025-11-19

PAX5 – a gene strongly associated with impaired insulin secretion in type 2 diabetes

Researchers have identified 395 genes that are differently expressed in people with type 2 diabetes. One of the genes proved to be very strongly associated with impaired insulin secretion. Now, researchers want to investigate if it is possible to use the genetic CRISPR/Cas9 scissors to correct the gene’s activity. The research team’s scientific paper was published in the Journal of Clinical Invest

https://www.ludc.lu.se/article/pax5-gene-strongly-associated-impaired-insulin-secretion-type-2-diabetes - 2025-11-19

A genetic-driven approach defining two obesity profiles that convey highly concordant and discordant diabetogenic effects

A team of researchers led by Daniel E. Coral and Paul W. Franks at LUDC have used human genetics to do a phenome-wide analysis of the degree of genetic dissimilarity between obesity and type 2 diabetes. Together with colleagues from Dundee and Oxford universities in the UK and the Vanderbilt Genetics Institute in the US, the team recently published their findings in the journal Nature Metabolism.

https://www.ludc.lu.se/article/genetic-driven-approach-defining-two-obesity-profiles-convey-highly-concordant-and-discordant - 2025-11-19

Swedish research about different forms of type 2 diabetes is relevant for Indian people

Researchers at Lund University have previously shown that type 1 diabetes and type 2 diabetes can be divided into five subgroups, and that there are genetic differences between the four subgroups relating to type 2 diabetes. A research collaboration between Sweden and India now highlights similarities and differences between patient groups in India and Europe. The knowledge can be used to improve

https://www.ludc.lu.se/article/swedish-research-about-different-forms-type-2-diabetes-relevant-indian-people - 2025-11-19

Epigenetics and genetics help illustrate how diabetes care can be individualised

Precision medicine aims to deliver the right treatment to the right person at the right time. What does this mean for people with type 2 diabetes? Some of the research at Lund University Diabetes Centre (LUDC) focuses on the progression of type 2 diabetes to help develop more targeted treatments. Epigenetics can become a useful tool when diabetes care is tailored to the individual. People with typ

https://www.ludc.lu.se/article/epigenetics-and-genetics-help-illustrate-how-diabetes-care-can-be-individualised - 2025-11-19

New discoveries about where atherosclerotic plaques rupture can lead to preventive treatments

A common cause of myocardial infarction and stroke is the rupture of atherosclerotic plaques. The exact location of plaque ruptures has previously been unknown, but now researchers at Lund University have mapped this. The research team has also identified an enzyme, a marker, that they hope will help predict who is at risk of having a myocardial infarction or a stroke due to a ruptured atheroscler

https://www.ludc.lu.se/article/new-discoveries-about-where-atherosclerotic-plaques-rupture-can-lead-preventive-treatments - 2025-11-19

Type 2 diabetes researchers receive support from the Hjelt Diabetes Foundation

Every year, the Bo and Kerstin Hjelt Diabetes Foundation awards three diabetes researchers at Lund University Diabetes Centre (LUDC) each a project grant of 47,500 euro. One of the researchers awarded a grant this year studies atherosclerotic plaques in patients with type 2 diabetes. These patients are more likely to develop cardiovascular disease due to plaque rupture compared to people without t

https://www.ludc.lu.se/article/type-2-diabetes-researchers-receive-support-hjelt-diabetes-foundation - 2025-11-19

Gut and mouth bacteria give researchers new clues about atherosclerosis

What is the link between atherosclerosis and gut and mouth bacteria? Researchers behind a large new study have found several new connections. In the long term, this knowledge can benefit people with type 2 diabetes, a group with an increased risk of developing atherosclerosis. In atherosclerosis, fat and calcium have accumulated in the artery walls over time, forming so called atherosclerotic plaq

https://www.ludc.lu.se/article/gut-and-mouth-bacteria-give-researchers-new-clues-about-atherosclerosis - 2025-11-19

Positive metabolic effects of gastric bypass disappear quickly

A new study from Lund University in Sweden raises questions about the efficacy of bariatric operations involving gastric bypass. The results show that the biggest metabolic changes happened directly after surgery. Just a year after the operation, the concentration of metabolites and fats had returned to almost the same levels as before the procedure.  Previous research has shown that the majority

https://www.ludc.lu.se/article/positive-metabolic-effects-gastric-bypass-disappear-quickly - 2025-11-19

New study: Virus of importance in the development of type 1 diabetes

New research supports the theory that certain viral infections are of importance in the development of type 1 diabetes. An international research team has discovered that young children with an increased genetic risk of type 1 diabetes had an increased risk of developing diabetes-related autoantibodies in connection with Covid-19 infection. Swedish children have contributed to the study which has

https://www.ludc.lu.se/article/new-study-virus-importance-development-type-1-diabetes - 2025-11-19

The Scientific Advisory Board: “Important contributions within type 1 diabetes research”

Lund University Diabetes Centre’s Scientific Advisory Board give researchers valuable feedback on ongoing research. Frances Ashcroft and Flemming Pociot from the board were invited to the LUDC retreat in the city of Helsingborg recently and they were impressed by the range of the research being performed at the centre. Research within type 1 diabetes specifically caught their attention. Frances As

https://www.ludc.lu.se/article/scientific-advisory-board-important-contributions-within-type-1-diabetes-research - 2025-11-19

New report highlights opportunities and challenges for precision diabetes medicine

An international consensus report on diabetes identifies the potential for diabetes screening, better classification of type 2 diabetes, and biomarkers that can predict cardiovascular disease. The report also highlights that more evidence is needed before it is possible to provide individualised treatment to all patients. The report is based on a large collaboration between 28 universities worldwi

https://www.ludc.lu.se/article/new-report-highlights-opportunities-and-challenges-precision-diabetes-medicine - 2025-11-19

Research on inherited type 2 diabetes is awarded

How do heritability and the fetal environment affect the risk for the child to develop type 2 diabetes? This is a question that Rashmi Prasad studies in her research projects that that may lead to individualised prevention measures. She will be awarded this year’s recipient Medeon stipend on the World Diabetes Day Skåne event on November 14. Diabetes researcher Rashmi Prasad at Lund University Dia

https://www.ludc.lu.se/article/research-inherited-type-2-diabetes-awarded - 2025-11-19

Innovation that aims to identify dangerous atherosclerotic plaques wins prize

Diabetes researcher and cardiologist Isabel Goncalves at Lund University Diabetes Centre (LUDC) has teamed up with ultrasound researchers at the Faculty of Engineering at Lund University (LTH) to identify dangerous atherosclerotic plaques at an early stage. The team is now being awarded Lund University’s and Sparbanken Skåne’s Future Innovations Award to develop their idea further. In atherosclero

https://www.ludc.lu.se/article/innovation-aims-identify-dangerous-atherosclerotic-plaques-wins-prize - 2025-11-19

Epigenetic changes can cause type 2 diabetes

Do epigenetic changes cause type 2 diabetes, or do the changes occur only after a person has become ill? A new study by researchers at Lund University provides increased support for the idea that epigenetic changes can cause type 2 diabetes. The researchers behind the new findings published in Nature Communications now aim to develop methods for disease prevention. We inherit our genes from our pa

https://www.ludc.lu.se/article/epigenetic-changes-can-cause-type-2-diabetes - 2025-11-19

New study: Biomarkers that improve prediction of cardiovascular disease in type 2 diabetes

An international team of researchers has identified 13 biomarkers that significantly improve the ability to accurately predict cardiovascular disease risk in people with type 2 diabetes. The analysis was led by Lund University, Johns Hopkins University, and the Chinese University of Hong Kong. The study was published in Communications Medicine. Although people with type 2 diabetes are two times mo

https://www.ludc.lu.se/article/new-study-biomarkers-improve-prediction-cardiovascular-disease-type-2-diabetes - 2025-11-19

The protein that protects insulin-producing cells

Much research on diabetes focuses on understanding what happens when the insulin-producing cells are destroyed. Researchers at Lund University have instead chosen to investigate what protects the insulin-producing cells. Their research shows that a protein of the immune system protects the insulin-producing cells from inflammation and death. The study, published in PNAS, is an example of basic res

https://www.ludc.lu.se/article/protein-protects-insulin-producing-cells - 2025-11-19

New coordinators for strategic research area in diabetes

Diabetes researchers Allan Vaag and Lena Eliasson are the new coordinators of Lund University Diabetes Centre (LUDC) and the strategic research area EXODIAB (Excellence of Diabetes Research in Sweden). Over the next years, they will work to strengthen and further develop ongoing collaborations. Coordinator Allan Vaag and Vice Coordinator Lena Eliasson are new leaders since the beginning of the yea

https://www.ludc.lu.se/article/new-coordinators-strategic-research-area-diabetes - 2025-11-19