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Validity of an algorithm to identify cardiovascular deaths from administrative health records: a multi-database population-based cohort study

A cardiovascular mortality algorithm applied to administrative health records had moderate validity when compared to vital statistics data. Substantial variation existed across study sites representing different geographic locations and two healthcare systems. These variations may reflect different diagnostic coding practices and healthcare utilization patterns. Read the paper at https://bmchealth

https://www.lupop.lu.se/article/validity-algorithm-identify-cardiovascular-deaths-administrative-health-records-multi-database - 2025-10-27

Reflection on modern methods: building causal evidence within high-dimensional molecular epidemiological studies of moderate size

This commentary provides a practical perspective on epidemiological analysis within a single high-dimensional study of moderate size to consider a causal question. Read the paper at https://academic.oup.com/ije/article/50/3/1016/6140018

https://www.lupop.lu.se/article/reflection-modern-methods-building-causal-evidence-within-high-dimensional-molecular-epidemiological - 2025-10-27

Future of surgical registries

The value of accurate healthcare data has never been more apparent than during the past year, and there is increasing recognition of the important role surgical registries play in driving improved patient outcomes, patient safety, and academic research. Successful registries need to be responsive and adapt to the rapidly changing clinical environment. Read the paper at https://academic.oup.com/bjs

https://www.lupop.lu.se/article/future-surgical-registries - 2025-10-27

Reflection on modern methods: causal inference considerations for heterogeneous disease etiology

Molecular pathological epidemiology research provides information about pathogenic mechanisms. A common study goal is to evaluate whether the effects of risk factors on disease incidence vary between different disease subtypes. Read the paper at https://academic.oup.com/ije/article/50/3/1030/6114706

https://www.lupop.lu.se/article/reflection-modern-methods-causal-inference-considerations-heterogeneous-disease-etiology - 2025-10-27

Labour and delivery ward register data availability, quality, and utility - Every Newborn - birth indicators research tracking in hospitals (EN-BIRTH) study baseline analysis in three countries

Countries with the highest burden of maternal and newborn deaths and stillbirths often have little information on these deaths. Since over 81% of births worldwide now occur in facilities, using routine facility data could reduce this data gap. We assessed the availability, quality, and utility of routine labour and delivery ward register data in five hospitals in Bangladesh, Nepal, and Tanzania. T

https://www.lupop.lu.se/article/labour-and-delivery-ward-register-data-availability-quality-and-utility-every-newborn-birth - 2025-10-27

Can the validity of a cohort be improved by reweighting based on register data? Evidence from the Swedish MDC study

We reweighted the Malmö Diet and Cancer (MDC) study based on population register data on background variables, including socio-demographics and hospital admissions for both participants and the background population. Following individuals from baseline in 1991-1996 and at most until 2016, we studied mortality (all-cause, cancer, and CVD), incidences (cancer and CVD), and associations between these

https://www.lupop.lu.se/article/can-validity-cohort-be-improved-reweighting-based-register-data-evidence-swedish-mdc-study - 2025-10-27

NordMAN facilitates researchers’ access to Nordic microdata and provides metadata on existing Nordic registers

A project jointly conducted by the Nordic national statistical institutes and funded by NordForsk was initiated in 2015. The project, Nordic Microdata Access Network (NordMAN), seeks to establish a single pan-Nordic solution to facilitate researchers' access to the Nordic metadata compiled for statistical purposes, and to provide an overview of the existing Nordic registers. The project’s common N

https://www.lupop.lu.se/article/nordman-facilitates-researchers-access-nordic-microdata-and-provides-metadata-existing-nordic - 2025-10-27

Exploring the impact of cancer registry completeness on international cancer survival differences: a simulation study

Data from population-based cancer registries are often used to compare cancer survival between countries or regions. The ICBP SURVMARK-2 study is an international partnership aiming to quantify and explore the reasons behind survival differences across high-income countries. However, the magnitude and relevance of differences in cancer survival between countries have been questioned, as it is argu

https://www.lupop.lu.se/article/exploring-impact-cancer-registry-completeness-international-cancer-survival-differences-simulation - 2025-10-27

Probabilistic Quantification of Bias to Combine the Strengths of Population-Based Register Data and Clinical Cohorts-Studying Mortality in Osteoarthritis

We propose combining population-based register data with a nested clinical cohort to correct misclassification and unmeasured confounding through probabilistic quantification of bias. We have illustrated this approach by estimating the association between knee osteoarthritis and mortality. We used the Swedish Population Register to include all persons resident in the Skåne region in 2008 and asses

https://www.lupop.lu.se/article/probabilistic-quantification-bias-combine-strengths-population-based-register-data-and-clinical-0 - 2025-10-27

The Validity of Intracerebral Hemorrhage Diagnoses in the Danish Patient Registry and the Danish Stroke Registry

Based on discharge summaries and brain imaging reports, we estimated the positive predictive value (PPV) of a first-ever diagnosis code for ICH (ICD-10, code I61) for all patients in the Region of Southern Denmark (1.2 million) during 2009– 2017 according to either DNPR or DSR. We estimated PPVs for any non-traumatic ICH (a-ICH) and spontaneous ICH (s-ICH) alone (ie, without underlying structural

https://www.lupop.lu.se/article/validity-intracerebral-hemorrhage-diagnoses-danish-patient-registry-and-danish-stroke-registry - 2025-10-27

The Israel Registry for Alzheimer’s Prevention (IRAP) Study: Design and Baseline Characteristics

Participants are members of the Maccabi Health Services, 40–65 years of age, with exquisitely detailed laboratory, medical diagnoses and medication data available in the Maccabi electronic medical records since 1998. Data collected through IRAP include genetic, sociodemographic, cognitive, brain imaging, lifestyle, and health-related characteristics at baseline and every three years thereafter. Re

https://www.lupop.lu.se/article/israel-registry-alzheimers-prevention-irap-study-design-and-baseline-characteristics - 2025-10-27

The Importance of Cancer Registry Linkage for Studying Rare Cancers in Prospective Cohorts

Large prospective cohort studies may offer an opportunity to study the etiology and natural history of rare cancers. Cancer diagnoses in observational cohort studies are often self-reported. Little information exists on the validity of self-reported cancer diagnosis, especially rare cancers, in Canada. This study evaluated the validity of self-reported cancer diagnosis in Alberta’s Tomorrow Projec

https://www.lupop.lu.se/article/importance-cancer-registry-linkage-studying-rare-cancers-prospective-cohorts - 2025-10-27

Administrative and Registry Databases for Patient Safety Tracking and Quality Improvement

Acquisition of data on clinical performance is essential to improve outcomes in surgery. Large, national datasets allow hospitals to monitor events involving patient safety, complications, and benchmark against peer hospitals and facilitate quality improvement (QI) development. Although clinical datasets are often preferable, administrative data also have potential for actionable QI. Hospitals sho

https://www.lupop.lu.se/article/administrative-and-registry-databases-patient-safety-tracking-and-quality-improvement - 2025-10-27

The validity of child and adolescent depression diagnoses in the Danish psychiatric central research register

A nationwide random sample of 500 children (6–17 years) diagnosed with depression between 1996 and 2016 was identified in the DPCRR. Psychiatric hospital records were reviewed and rated using an online checklist. The primary outcome was whether depressive symptoms and functional impairment documented in hospital records justified a depressive disorder diagnosis based on ICD‐10 or DSM‐5 diagnostic

https://www.lupop.lu.se/article/validity-child-and-adolescent-depression-diagnoses-danish-psychiatric-central-research-register - 2025-10-27

Developing a trauma registry in a middle-income country - Botswana

A cross sectional study was piloted at a tertiary hospital and a secondary level hospital in Botswana. The study consisted of two stages: stage 1 - stakeholders' consultation and trauma registry prototype was designed. Stage 2 consisted of two phases: Phase I involved retrospective collection of existing data from existing data collection tools and Phase II collected data prospectively using the p

https://www.lupop.lu.se/article/developing-trauma-registry-middle-income-country-botswana - 2025-10-27

The validity of child and adolescent depression diagnoses in the Danish psychiatric central research register

A nationwide random sample of 500 children (6–17 years) diagnosed with depression between 1996 and 2016 was identified in the DPCRR. Psychiatric hospital records were reviewed and rated using an online checklist. The primary outcome was whether depressive symptoms and functional impairment documented in hospital records justified a depressive disorder diagnosis based on ICD‐10 or DSM‐5 diagnostic

https://www.lupop.lu.se/article/validity-child-and-adolescent-depression-diagnoses-danish-psychiatric-central-research-register-0 - 2025-10-27

Population research awarded the Färs and Frosta Prize

Anna Tegunimataka awarded prize for best dissertation at LUSEM Anna Tegunimataka, who finished her PhD in economic history last June, has been awarded the Färs and Frosta Prize for best doctoral dissertation at LUSEM. The prize is 100,000 SEK. The titel of her thesis is: Trajectories of Integration: Naturalization, Intermarriage and Education in Denmark, 1980-2015

https://www.lupop.lu.se/article/population-research-awarded-fars-and-frosta-prize - 2025-10-27