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Scientists uncover cellular “toolkit” to reprogram immune cells for cancer therapy

Members of the Pereira Lab: Luís Oliveira, Ilia Kurochkin, Filipe Pereira and Abigail Altman. Photo: Kennet Ruona An international team led by researchers at Lund University in Sweden has identified the molecular tools needed to reprogram ordinary cells into specialised immune cells. The discovery, published in Immunity, could pave the way for more precise and personalised cancer immunotherapies.

https://www.medicine.lu.se/article/scientists-uncover-cellular-toolkit-reprogram-immune-cells-cancer-therapy - 2025-09-13

Urine test can assess risk of kidney cancer recurrence

A new international study with 134 patients from 23 hospitals in ten countries shows that a simple urine test can cut the number of radiological examinations in half. Photo: iStock A simple urine test that can assess the risk of kidney cancer recurrence at an early stage could spare patients from frequent imaging scans, e.g. CT-scans, and thus reduce the associated radiation, anxiety and costs. Th

https://www.medicine.lu.se/article/urine-test-can-assess-risk-kidney-cancer-recurrence - 2025-09-13

New global initiative on maternal and newborn health to be led from Sweden

Mehreen Zaigham, Associate Professor at Lund University and specialist in Obstetrics and Gynaecology, Skåne University Hospital, is chairing the upcoming Lancet Commission. Photo: Ingemar Hultquist A new international commission will pave the way for a global boost in maternal and newborn health. The project is led by a researcher at Lund University in Sweden, whose motivation stems from a formati

https://www.medicine.lu.se/article/new-global-initiative-maternal-and-newborn-health-be-led - 2025-09-13

ERC grants awarded to research on the interplay between immunology and fertility, and Alzheimer's disease

Jacob Vogel and Camila Consiglio are awarded The European Research Council (ERC) Starting Grants to develop their research projects and to building their own research team. Photo: Ingemar Hultquist Congratulations to Jacob Vogel and Camila Consiglio who have been awarded grants to develop their research projects on Alzheimer's and fertility. Camila Consiglio's research focuses on infertility and t

https://www.medicine.lu.se/article/erc-grants-awarded-research-interplay-between-immunology-and-fertility-and-alzheimers-disease - 2025-09-13

Highlights from the Lund Spring Symposium 2025

Lars Grundemar is head of research group and adjunct professor of clinical pharmacology at Lund University, and the initiator and chair of the Lund Spring Symposium. Photo: Tove Smeds From Nobel Prizes to visions of the future – over a few days in May, world-leading medical researchers and biotech pioneers gathered to discuss new molecular therapies: from genetic fundamentals to clinical breakthro

https://www.medicine.lu.se/article/highlights-lund-spring-symposium-2025 - 2025-09-13

Science, Responsibility and Resilience – A Conversation on the Future of Medicines

Mikael Dolsten (left) and Jan M. Lundberg (center) in a conversation moderated by Adam Smith, Nobel Prize Outreach (right). Photo: Tove Smeds. At this year’s Lund Spring Symposium, two veteran leaders of pharmaceutical research – Jan M. Lundberg and Mikael Dolsten – engaged in a wide-ranging conversation about scientific courage, setbacks, technological leaps, and hope for the future. The 2025 edi

https://www.medicine.lu.se/article/science-responsibility-and-resilience-conversation-future-medicines - 2025-09-13

RNAi: A Genetic Spark in the Information Inferno of the Cell

Nobel Laureate in Physiology or Medicine 2006, Craig Mello, professor at the University of Massachusetts, Chan Medical School, USA. Photo: Tove Smeds. The information age predates the internet by a long stretch – it began with life itself. Nobel Laureate Craig C. Mello described at the Lund Spring Symposium in May how living organisms are not merely carriers of genes, but also active managers, def

https://www.medicine.lu.se/article/rnai-genetic-spark-information-inferno-cell - 2025-09-13

Rewriting Genetic Fate: Katherine High and the Rise of Gene Therapy

Kathrine High, visiting professor at Rockefeller University, CEO of RhyGaze AG, and former president and chief scientific officer at Spark Therapeutics. Photo: Tove Smeds. LUND SPRING SYMPOSIUM – When Katherine A. High began working with gene therapy, the field was new, promising – and riddled with uncertainty. Three decades later, she is a visiting professor at The Rockefeller University, CEO of

https://www.medicine.lu.se/article/rewriting-genetic-fate-katherine-high-and-rise-gene-therapy - 2025-09-13

Innovative ideas and pioneering solutions from Lund University celebrated

Yvonne Lundberg Giwercman received the award for the development of a point-of-care test that can greatly improve the outcome of IVF treatments. An innovative IVF test and a methane detector – these are some of the future innovation stars developed at Lund University. They are now being recognised by the University and Sparbanken Skåne. Since its launch in 2017, the Future Innovations Award has re

https://www.medicine.lu.se/article/innovative-ideas-and-pioneering-solutions-lund-university-celebrated - 2025-09-13

Award-winning cancer researcher revolutionises diagnosis and treatment worldwide

"Stronger support functions such as LU Innovation, incubators and Medicon Village in Lund have been developed in a fantastic way and enable research to be transformed more quickly into solutions that reach wider society,” says Thoas Fioretos. Professor Thoas Fioretos is the first recipient of Lunds Innovatörspris (the Lund Innovator Award), a newly established prize that recognises research that h

https://www.medicine.lu.se/article/award-winning-cancer-researcher-revolutionises-diagnosis-and-treatment-worldwide - 2025-09-13

First major study of proteins in patients with acute lymphoblastic leukaemia

The most common form of childhood cancer is acute lymphoblastic leukaemia (ALL). Researchers at Lund University in Sweden, in cooperation with Karolinska Institutet, SciLifeLab and the University of Cambridge, have now carried out the most extensive analysis to date of ALL at the protein level, by studying the activity in over 8 000 genes and proteins. The results show aberrant folding in the DNA

https://www.medicine.lu.se/article/first-major-study-proteins-patients-acute-lymphoblastic-leukaemia - 2025-09-13

Honorary lecturer Feng Zhang: CRISPR research – a treasure hunt in nature

Feng Zhang and Malin Parmar (Photo: Ingemar Hultquist) Feng Zhang, professor at the Broad Institute of MIT and Harvard visited Lund University at the beginning of March to deliver the annual honorary lecture organised by the Royal Physiographic and Mendelian Societies in Lund. First published: 2019-05-26Listen to the interview and hear more about why Feng Zhang wants to introduce a moratorium on g

https://www.medicine.lu.se/article/honorary-lecturer-feng-zhang-crispr-research-treasure-hunt-nature - 2025-09-13

Gestational diabetes in India and Sweden

First published: 2019-05-03Indian women are younger and leaner than Swedish women when they develop gestational diabetes, a new study from Lund University shows. The researchers also found a gene that increases the risk of gestational diabetes in Swedish women, but which, on the contrary, turned out to have a protective effect in Indian women.Gestational diabetes is characterized by impaired insul

https://www.medicine.lu.se/article/gestational-diabetes-india-and-sweden - 2025-09-13

New view on the mechanisms of how the brain works

Henrik Jörntell and Jonas Enander After a series of studies, researchers at Lund University in Sweden, together with colleagues in Italy, have shown that not only one part, but most parts of the brain can be involved in processing the signals that arise from touch. The results open the way for a new approach to how the brain’s network of neurons processes information, and thereby the mechanisms by

https://www.medicine.lu.se/article/new-view-mechanisms-how-brain-works - 2025-09-13

Study shows increase in parasite disease in Sweden

The number of cases of disease caused by Leishmania, a parasite that is spread via bites by sand flies which are mainly found in tropical and subtropical areas and in countries around the Mediterranean, has increased in Sweden. The most serious form of the disease usually leads to death if untreated. First published: 2019-05-06“This disease is still very rare in Sweden but the number of cases has

https://www.medicine.lu.se/article/study-shows-increase-parasite-disease-sweden - 2025-09-13

First large-scale study of proteins in patients with ALL

The most common form of childhood cancer is acute lymphoblastic leukaemia (ALL). Together with Karolinska Institutet, SciLifeLab and the University of Cambridge, researchers at Lund University have conducted the largest ever analysis of ALL at protein level by studying activity in more than 8,000 genes and proteins. The results of the study show a deviant folding of the DNA strand which in turn af

https://www.medicine.lu.se/article/first-large-scale-study-proteins-patients-all - 2025-09-13

Accessibility in the home is the key for a person with a spinal cord injury

Being able to take care of one’s hygiene, cook food and cope independently in the home are examples of feeling in control of one’s life. But how easy is it for an elderly person with a spinal cord injury to feel actively in control of their life in the home? Lizette Norin, occupational therapist and researcher, has written a thesis on the importance of accessibility in the home. First published: 2

https://www.medicine.lu.se/article/accessibility-home-key-person-spinal-cord-injury - 2025-09-13

Nominate projects for the Mats Paulsson Foundation

Applications for the nomination of academic innovation projects and medium-cost equipment to the Mats Paulsson Foundation for Research, Innovation and Community Development First published: 2019-05-06In the text below, the Mats Paulsson Foundation for Research, Innovation and Community Development describes the purpose of the announcement and how applications are to be structured.The Foundation ha

https://www.medicine.lu.se/article/nominate-projects-mats-paulsson-foundation - 2025-09-13

Researchers block protein that plays a key role in Alzheimer’s disease

Tomas Deierborg and Antonio Boza-Serrano In recent years, it has become increasingly clear to researchers that the protein galectin-3 is involved in inflammatory diseases in the brain. A study led by researchers at Lund University in Sweden now shows the de facto key role played by the protein in Alzheimer’s disease. When the researchers shut off the gene that produces this protein in mice, the am

https://www.medicine.lu.se/article/researchers-block-protein-plays-key-role-alzheimers-disease - 2025-09-13

An additional SEK 50 million to research on the brain’s mechanisms

A European consortium, led from Lund University, is to receive SEK 50 million from the EU for research which is to develop our understanding of the functional mechanisms of the brain. The research project, called INTUITIVE, is one of the Innovative Training Networks within the framework of Horizon 2020. The aim of the project is to develop user interfaces based on touch that feel more intuitive th

https://www.medicine.lu.se/article/additional-sek-50-million-research-brains-mechanisms - 2025-09-13