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Fine-tuning neural circuits to heal the brain – Segerfalk lecturer Andres Lozano on next-gen neurosurgery

In a world facing rising mental health challenges, neurodegenerative diseases and the limits of current treatments, Andres Lozano’s work points to a future where sound, light and a code may become some of medicine’s most powerful tools. LONGREAD. He treats tremor with sound waves, is preparing to help paralyzed patients control a cursor with their thoughts and envisions a future where brain and ma

https://www.medicine.lu.se/article/fine-tuning-neural-circuits-heal-brain-segerfalk-lecturer-andres-lozano-next-gen-neurosurgery - 2025-08-27

More opportunities to test for Alzheimer’s using new analytical method

“Even with the simpler method of analysis, the blood test gives highly accurate results for Alzheimer’s disease pathology,” says Sebastian Palmqvist, associate professor and senior lecturer in neurology at Lund University. Photo: iStock A simpler method of analysing blood samples for Alzheimer’s disease has been tested in a large multicentre study, led by Lund University in Sweden. “This is a majo

https://www.medicine.lu.se/article/more-opportunities-test-alzheimers-using-new-analytical-method - 2025-08-27

From molecule to patient – Six promising projects to advance Parkinson's research

April is Parkinson’s Awareness Month. Globally, around 10 million people are affected by Parkinson’s disease—a condition where neurons in brain areas controlling movement gradually degenerate. Photo: Emma Nyberg What role does an inflammatory protein have in disease development? Which neuronal circuits cause different symptoms? How may diabetes affect Parkinson’s disease? Can motor signs be identi

https://www.medicine.lu.se/article/molecule-patient-six-promising-projects-advance-parkinsons-research - 2025-08-27

Simple medication can save the lives of cardiac patients

“Today’s guidelines recommend stepwise addition of lipid-lowering treatment. But it’s often the case that this escalation takes too long, it’s ineffective and patients are lost to follow-up", says Margrét LeósdóttirPhoto: Åsa Hansdotter Patients suffering from myocardial infarction who receive early add-on lipid-lowering medication have a significantly better prognosis than those who receive add-o

https://www.medicine.lu.se/article/simple-medication-can-save-lives-cardiac-patients - 2025-08-27

Lund Stem Cell Center welcomes a new leadership team

The Lund Stem Cell Center at Lund University welcomes the beginning of a new chapter with the appointment of its new leadership team. As of January 1, 2025, Professor Malin Parmar has assumed the role of Director, with Associate Professor Göran Karlsson stepping in as Deputy Director. Together, they bring decades of expertise, deep connections to the Lund research community, and a shared vision fo

https://www.medicine.lu.se/article/lund-stem-cell-center-welcomes-new-leadership-team - 2025-08-27

Protein changes reveal diseases

Photo: Åsa Hansdotter Researchers at Lund University have developed a new method to determine how the composition of proteins in blood changes in response to disease or organ damage. This could provide a deeper understanding of how diseases affect the body and be used to discover new biomarkers in the blood to aid in diagnosing complex medical conditions. Our organs consist of a variety of specifi

https://www.medicine.lu.se/article/protein-changes-reveal-diseases - 2025-08-27

Higher success rate using a simple oral swab test before IVF

The researchers could see an increase in the number of pregnancies and a relative number of 38% more babies born among women who received hormone therapy that matched their gene variation compared with those who did not. Photo: iStock Researchers at Lund University in Sweden have conducted a clinical study to show how a woman’s genetic profile provides information on which hormone treatment is mos

https://www.medicine.lu.se/article/higher-success-rate-using-simple-oral-swab-test-ivf - 2025-08-27

8.3 million euros for doctoral programme in regenerative medicine and ATMP

Marie Jönsson, grant manager Stem Cell Center and Mattias Magnusson, director of RAMP-UP at the Lund Research School in Stem Cell Biology and group leader at the Stem Cell Center. Photo: Alexis Bento Luis Lund University in Sweden has been awarded an EU grant of 8.3 million euros for a new international doctoral programme in regenerative medicine and advanced therapy medicinal products. The aim is

https://www.medicine.lu.se/article/83-million-euros-doctoral-programme-regenerative-medicine-and-atmp - 2025-08-27

Lund University's virus centre inaugurated with symbolic demolition of giant virus

There was no ribbon-cutting, but a symbolic demolition of a 3D-printed giant virus. Photo: Agata Garpenlind Lund University Virus Centre (LUVC) holds festive inauguration (May 27). There was no ribbon-cutting ceremony, but instead a symbolic demolition of a 3D-printed giant virus marked the official opening of the virus centre.Three deans—current and former—as well as professors who have succeeded

https://www.medicine.lu.se/article/lund-universitys-virus-centre-inaugurated-symbolic-demolition-giant-virus - 2025-08-27

New gene variants significantly increase the risk of blood clots

Bengt Zöller and his fellow researchers have now identified the strongest genetic risk factor since Factor V Leiden was discovered. Photo: Åsa Hansdotter Blood clots can form in both arteries and veins. However, the reasons behind them differ, as do the consequences and the chances of preventing blood clots. In Sweden, almost half of all cases of venous thrombosis have a genetic explanation. A tea

https://www.medicine.lu.se/article/new-gene-variants-significantly-increase-risk-blood-clots - 2025-08-27

Link identified between low-fibre diet and the more dangerous type of atherosclerotic plaque in the coronary arteries

The study's results indicate a link between the food we eat and serious heart problems caused by atherosclerotic plaques, such as heart attacks. Photo: iStock A Swedish multi-centre study led by researchers at Lund University shows a link between low fibre consumption and the presence of unstable or high-risk plaque in coronary arteries – the type of plaque that can trigger blood clots and cause h

https://www.medicine.lu.se/article/link-identified-between-low-fibre-diet-and-more-dangerous-type-atherosclerotic-plaque-coronary2 - 2025-08-27

How to turn research ideas into a real-world impact

Professors Thoas Fioretos, Lao Saal, Carl Borrebaeck and Åke Borg are behind some of the most promising companies and approaches within diagnostics and treatment emerging from cancer research at Lund University. Photo: Tove Smeds, Olle Dahlbäck. Professors Carl Borrebaeck, Thoas Fioretos, Lao Saal and Åke Borg share their experiences in transforming groundbreaking research into diagnostic tools, t

https://www.medicine.lu.se/article/how-turn-research-ideas-real-world-impact - 2025-08-27

Charlotte Ling receives major grant for clinical diabetes research

Charlotte Ling, who together with Katarina Fagher and Alice Maguolo, has been awarded a grant of five million Danish kroner by the Novo Nordisk Foundation. Photo: Kennet Ruona Congratulations to Charlotte Ling who, together with Katarina Fagher and Alice Maguolo, has been awarded a grant of five million Danish kroner by the Novo Nordisk Foundation. The funding will support clinical research in pre

https://www.medicine.lu.se/article/charlotte-ling-receives-major-grant-clinical-diabetes-research - 2025-08-27

Brain activation pattern behind impulsivity in Parkinson’s treatment discovered

he researchers stained brain sections to identify how different Parkinson’s treatments activate distinct brain circuits. Photo: Emma Nyberg. An experimental study from Lund University reveals for the first time that different Parkinson’s medications affect brain activity in distinct ways. This could explain why some patients develop impulsive and compulsive behaviors as a result of their treatment

https://www.medicine.lu.se/article/brain-activation-pattern-behind-impulsivity-parkinsons-treatment-discovered - 2025-08-27

Brussels meeting: Advancing personalised treatment for childhood AML across Europe

The NOPHO-DB-SHIP consortium at last year's meeting in Utrecht, NL. Photo: Private In June, pediatric cancer experts from 16 countries gathered in Brussels for the annual meeting of the NOPHO-DB-SHIP consortium—an EU-wide collaboration working to improve outcomes for children with Acute Myeloid Leukemia (AML). In Sweden, the trial is coordinated by Lund University and Skåne University Hospital. At

https://www.medicine.lu.se/article/brussels-meeting-advancing-personalised-treatment-childhood-aml-across-europe - 2025-08-27

Aggressive skin cancer driven by mitochondrial processes –existing drugs offer promising treatment path

Jeovanis Gil, researcher in clinical chemistry at Lund University, focuses extensively on understanding mitochondrial roles in melanoma and other cancers. Photo: Tove Smeds A new study led by researchers at Lund University in Sweden, reveals that melanoma, the deadliest form of skin cancer, can in some cases be driven by mitochondrial processes, which can be effectively targeted using existing dru

https://www.medicine.lu.se/article/aggressive-skin-cancer-driven-mitochondrial-processes-existing-drugs-offer-promising-treatment-path - 2025-08-27

Biomarkers reveal risk of cardiovascular disease in type 2 diabetes

Charlotte Ling and colleagues want to develop a kit for clinical use to predict the risk of cardiovascular disease in type 2 diabetes: a simple blood test that measures DNA methylation and a scoring scale that predicts the risk of disease. Photo: K Ruona. An international research team led from Lund University, has identified epigenetic biomarkers that can predict which people with type 2 diabetes

https://www.medicine.lu.se/article/biomarkers-reveal-risk-cardiovascular-disease-type-2-diabetes - 2025-08-27

Children waiting for a new heart –study shows marked improvement in survival rates and the importance of Nordic cooperation

The researchers have mapped how the outcomes for heart-transplanted children have changed over time and examined how the results compare in an international context. Photo: iStock In a new observational study, researchers at Lund University in Sweden looked at all children listed for heart transplants in the Nordic countries between 1986 and 2023. A total of 597 children were included in the study

https://www.medicine.lu.se/article/children-waiting-new-heart-study-shows-marked-improvement-survival-rates-and-importance-nordic - 2025-08-27

Hjelt Diabetes Foundation supports research that can pave the way for new cell therapies

Sevda Gheibi studies a protein called ACSL1 that seems to play a key role for beta cell function. She receives a grant of from the Hjelt Diabetes Foundation for further studies of this protein. Photo: Petra Olsson Type 2 diabetes is a chronic disease that usually requires lifelong treatment. A central goal for many diabetes researchers is to develop new cell therapies that can cure the disease. Th

https://www.medicine.lu.se/article/hjelt-diabetes-foundation-supports-research-can-pave-way-new-cell-therapies - 2025-08-27

Why repetitive DNA matters for human brain evolution and disease

“An underlying question in my lab is: how did the human brain become human?” says Johan Jakobsson, professor at the Department of Experimental Medical Science and head of the Laboratory of Molecular Neurogenetics For decades, large stretches of human DNA were dismissed as ‘junk’ and considered to serve no real purpose. In a new study in Cell Genomics, researchers at Lund University in Sweden show

https://www.medicine.lu.se/article/why-repetitive-dna-matters-human-brain-evolution-and-disease-0 - 2025-08-27