Background: Radiotherapy increases survival in patients with glioblastoma. However, the prescribed dose is limited by unwanted side effects on normal tissue. Previous experimental studies have shown that FLASH radiotherapy (FLASH-RT) can reduce these side effects. Still, it is important to establish an equal anti-tumor efficacy comparing FLASH-RT to conventional radiotherapy (CONV-RT). Methods: Fu

Micronutrients and physical stability of milk and cream were evaluated for different heat treatments at dairy production scale (HTST pasteurisation, high pasteurisation, ESL indirect and UHT direct and indirect). Changes caused due to heat treatments for macro and micro components (vitamins and minerals) as well as physical stability were investigated. Results show limited losses in macro componen

Introduction: Magnetic skyrmions hold great promise for realizing compact and stable memory devices that can be manipulated at very low energy costs via electronic current densities. Methods: In this work, we extend a recently introduced method to describe classical skyrmion textures coupled to dynamical itinerant electrons. In this scheme, the electron dynamics is described via nonequilibrium Gre

Given that eco-innovations and the associated renewal of regional economic structures are pivotal in addressing environmental challenges, regional research is increasingly focusing on their spatio-temporal dynamics. While green technological and industrial path developments in specific regions have received considerable attention, little effort has been made to derive general patterns of environme

We propose an observer for rotational dynamics subject to directional and gyroscopic measurements, which simultaneously estimates the gyroscopic biases and attitude rates. We show uniform almost global asymptotic and local exponential stability of the resulting error dynamics, implying robustness against bounded disturbances. This robustness is quantified with respect to a popular nonlinear comple

BACKGROUND: Suicidal behavior and substance use disorders (SUDs) are important public health concerns. Prior suicide attempts and SUDs are two of the most consistent predictors of suicide death, and clarifying the role of SUDs in the transition from suicide attempt to suicide death could inform prevention efforts. METHODS: We used national Swedish registry data to identify individuals born 1960-19

Objectives: To determine pre-operative cleft volume and evaluate cleft´s impact on surrounding anatomical structures in children and adolescents with orofacial clefts using cone bean computed tomography (CBCT) imaging. Methods: The present retrospective study retrieved CBCT examinations of 68 patients from a previous study. The examinations had been exposed either before (n = 53) or after (n = 15)

Rapporten är resultatet av ett tvåårigt samarbetsprojekt mellan Centrum för Näringslivshistoria och Statens maritima och transporthistoriska museer, finansierat av Trafikverkets FoI-medel. Förstudien syftar till att undersöka de väg-, civilflygs- och järnvägshistoriska samlingarnas potential som källa till historisk och annan forskning och som resurs i Trafikverkets planering och verksamhet. Målsä

Rapporten presenterar ett uppdaterad planeringsverktyg för Bus Rapid Transit (BRT), anpassat för en svensk kontext. Planeringsverktyget är tänkt att fungera som ett samverkansstöd för planerare och består av 25 olika parametrar fördelat på 4 olika kategorier; Stadens utformning, Kollektivtrafikens infrastruktur, Fordon och stödsystem samt Trafikering.

Objectives: Depression is increasing and is a leading cause of disease burden among adolescents. Available evidence-based treatments with medication or psychotherapy have modest effects. Aerobic exercise is a hopeful alternative as an augmenter or a stand-alone treatment. Qualitative studies have shown that participants in group exercise for adolescent depression experienced improved mood and a se

The dating of moraine deposits can present challenges to standard geochronological methods; terrestrial cosmogenic nuclide (TCN), sediment luminescence and radiocarbon dating may suffer from problems of incomplete resetting (by inheritance, intermittent cover/exposure, transport under unfavourable conditions) and/or a lack of suitable (organic) material. Rock surface luminescence burial dating (RS

Coarse-graining techniques play a central role in reducing the complexity of stochastic models and are typically characterized by a mapping which projects the full state of the system onto a smaller set of variables which captures the essential features of the system. Starting with a continuous-time Markov chain, in this work we propose and analyze an effective dynamics, which approximates the dyn

We here report the synthesis of the homoleptic iron(II) N-heterocyclic carbene (NHC) complex [Fe(miHpbmi)2](PF6)4 (miHpbmi = 4-((3-methyl-1H-imidazolium-1-yl)pyridine-2,6-diyl)bis(3-methylimidazol-2-ylidene)) and its electrochemical and photophysical properties. The introduction of the π-electron-withdrawing 3-methyl-1H-imidazol-3-ium-1-yl group into the NHC ligand framework resulted in stabilizat

The article discusses the importance of adopting a human rights-based approach in addressing the lessons learned from the Covid-19 pandemic. The article highlights the case of a human rights-based hospital in Sweden that actively reached out to vulnerable individuals in the community during the pandemic, emphasizing how the human rights-based approach contributes to building trust and thereby real

There are apparent similarities between the parables contained in the Gospels and those found in the Qurʾān, which provide their audiences with illustrations of complex religious concepts and moral teachings through the imagery of everyday life. Based on the form-critical analysis of the Gospel Parable of the Sower and some Qurʾānic parables, this article aims to detect defining similarities and d

We have previously reported the first formal hydroamination of enamines for the synthesis of chiral 1,2-diamines. Here, we describe: (i) the discovery, optimization, and substrate expansion of this reaction; (ii) a novel and straightforward protocol for the “click-type” synthesis of enamines in quantitative yield utilizing sodium sulfate in a dual role as an ancillary and dehydrating agent without

Background: Intraductal papillary neoplasm of the bile ducts (IPNB) is a rare disease in Western countries. The aim of this study was to compare tumor characteristics, management strategies, and outcomes between Western and Eastern patients who underwent surgical resection for IPNB. Methods: A multi-institutional retrospective series of patients with IPNB undergoing surgery between January 2010 an

Luminescence properties of a palmierite-type K5Eu(MoO4)4 crystal were studied in a wide temperature range of 7-650 K. Eu3+ ions are shown to occupy at least three non-equivalent positions in the palmierite-type structure, forming emission centres with slightly different characteristics due to an incommensurate modulated disordering. The relative intensity of the Eu3+ emission bands originating fro