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Det idag väldigt populära riskmåttet Value-at-Risk (VaR) kan beräknas på många olika sätt. En metod som använder sig av extremvärdesteori (EVT) för att estimera VaR utvecklades under 1990-talet som ett alternativ till de traditionella VaR metoderna. EVT fokuserar på fördelningens svans, eftersom det är här de extrema observationerna uppträder. I denna studie undersöker vi hur framgångsrik extremvä

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In this essay I examine the causal relationship between confidence in institutions and growth in Sweden 1989-2002. By examining the causal relationship between these two variables, valuable indicators of the causal relationship between trust and growth can be obtained. The institutions which are used in this essay are chosen according to the theory on institutions for public administration buildin

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Förr i tiden producerades musik med analog hårdvara och datorer användes inte i någon vidare utsträckning. På 80-talet introducerades datorer och nu produceras nästan all musik med hjälp av datorer. Denna uppsats belyser om, och i så fall hur, införandet av datorer i musikproduktion har påverkat musikproducenter i deras arbete i vardagen. Vi har intervjuat ett antal musikproducenter för att se hur

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I takt med att handeln med finansiella tillgångar ökat har också intresset för att finna tillförlitliga metoder att bedöma risken ökat. Ett mått för att mäta risken för en tillgång eller för en portfölj av tillgångar är Value-at-Risk (VaR). VaR definieras som; den med viss sannolikhet förväntade förlusten från ogynnsamma marknadsrörelser över en definierad tidsperiod. Fördelen med VaR är att riskb

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Product placement, the cooperative effort of advertisers and creators of entertainment products in which trademarked goods are embedded into popular entertainment products to encourage their consumption, overriding entertainment and artistic concerns is becoming a mayor player in TV economics. The means in which this marketing measure may be practised in Sweden are regulated by legal rules and sel

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PURPOSE Effective treatments are needed for melanoma that progresses on inhibitors of programmed cell death protein-1 (PD-1) or its ligand (PD-L1). We conducted the phase II LEAP-004 study to evaluate the combination of the multikinase inhibitor lenvatinib and the PD-1 inhibitor pembrolizumab in this population (ClinicalTrials.gov identifier: NCT03776136).METHODSEligible patients with unresectable

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Research Question/Issue: Motivated by the agency theory and the findings of linguistic studies, we analyze the association between the internationalization of a firm's audit committee and its corporate governance. Research Findings/Insights: Based on data from 2159 publicly traded European firms from 15 countries for the period 2000–2018, we find that firms with foreign directors on their audit co

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Microbes inhabiting deep soil layers are known to be different from their counterpart in topsoil yet remain under investigation in terms of their structure, function, and how their diversity is shaped. The microbiome of deep soils (>1 m) is expected to be relatively stable and highly independent from climatic conditions. Much less is known, however, on how these microbial communities vary along cl

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Introduction: The ancient city of Tel Megiddo in the Jezreel Valley (Israel), which lasted from the Neolithic to the Iron Age, has been continuously excavated since 1903 and is now recognized as a World Heritage Site. The site features multiple ruins in various areas, including temples and stables, alongside modern constructions, and public access is allowed in designated areas. The site has been

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Melanin pigments play a critical role in physiological processes and shaping animal behaviour. Fossil melanin is a unique resource for understanding the functional evolution of melanin but the impact of fossilisation on molecular signatures for eumelanin and, especially, phaeomelanin is not fully understood. Here we present a model for the chemical taphonomy of fossil eumelanin and phaeomelanin ba

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Objectives: This is a protocol for a Cochrane Review (intervention). The objectives are as follows:. To assess the success rate of the lateral decubitus, sitting and prone positions for lumbar puncture in newborn infants.

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Background: Optimal fluid status is an important issue in hemodialysis. Clinical evaluation of volume status and different diagnostic tools are used to determine hydration status in these patients. However, there is still no accurate method for this assessment. Purpose: To propose and evaluate relative lean water signal (LWSrel) as a water–fat MRI-based tissue hydration measurement. Study Type: Pr

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Tbx4 protein, expressed in mesenchyme of the developing lung, contributes to airway branching and distal lung growth. An association between pediatric onset of pulmonary arterial hypertension (PAH) and genetic variations coding for the T-box transcription factor 4 gene (TBX4) has been increasingly recognized. Tbx4-related PAH onset has a bimodal age distribution, including severe to lethal PAH in

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We carried out deep mapping observations of the atomic hydrogen (H i) 21 cm line emission in a field centered on the famous galaxy group Stephan's Quintet (SQ), using the Five-hundred-meter Aperture Spherical Telescope (FAST) equipped with a 19-beam receiver. The final data cube reaches an H i column density sensitivity of 5σ = 2.1 × 1017 cm-2 per 20 km s-1 channel with an angular resolution of 4.

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Background: There are two primary phenotypic models of comorbidity between post-traumatic stress disorder (PTSD) and drug use disorder (DUD), i.e. self-medication (PTSD precedes and causes DUD) and susceptibility (DUD precedes and causes PTSD). We sought to clarify the longitudinal relationship between PTSD and DUD, while examining sex differences. Method: We used approximately 23 years of longitu

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This article sheds light upon the cultural politics of fear in post-war Nepal by narrowing in on the Nepal banda–a recurring political spectacle in which the organizers seek to shut down Nepalese society through violent means–tracing both how it shapes and is appropriated in (offline and online) everyday life. In doing so I demonstrate how the online tactics that people employ to navigate the Nepa

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In recent years, detailed studies of three-pion systems have become possible in lattice QCD. This has in turn led to interest in 3-to-3 scattering of pions in the chiral perturbation theory framework. In addition to being an interesting study of multi-meson dynamics in its own right, it provides a valuable handle on finite-volume effects and the pion mass dependence, thus complementing the lattice

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We report confocal microscopy experiments of electric-field-driven crystal-crystal transformations in microgel colloids with varying particle softness. The transformation kinetics are well described by phenomenological nucleation and growth theory. Using a spatial projection formalism, we determine local susceptibilities to affine shear deformation and nonaffine defect formation in the parent crys

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Starting from the recently proposed dynamical exchange-correlation field framework, the equation of motion of the diagonal part of the many-electron Green function is derived, from which the spectral function can be obtained. The resulting equation of motion takes the form of the continuity equation of charge and current densities in electrodynamics with a source. An unknown quantity in this equat

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Background: There is limited information on the distribution of retroperitoneal lymph node metastases (LNMs) in upper tract urothelial carcinoma (UTUC). Objective: To investigate the location of LNMs in UTUC of the renal pelvis or proximal ureter and short-term complications after radical nephroureterectomy (RNU) with lymph node dissection (LND). Design, setting, and participants: This was a prosp