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Intermittent hypoxia (IH), the defining physiological feature of obstructive sleep apnea, has been strongly linked to cardiovascular morbidity, yet the early myocardial effects of short-term IH remain poorly characterized. In this study, we investigated whether brief IH exposure elicits adaptive anti-apoptotic signaling or early injurious activation of intrinsic apoptotic pathways in the murine he

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Varför är Sverigedemokraterna intresserade av historia när så få andra politiska partier i vår samtid verkar vara det? Vilken historia är det som lockar och hur görs den till politiska poänger? Svaren finns i deras nationalistiska ideologi. Här ses historien genom ett särskilt prisma där nationalismen avgör hur händelser och personer framträder. Genom att konstruera existensen av en nationell ödes

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We demonstrate that the weak gravity conjecture (WGC) and the Festina-Lente conjecture (FLC) yield novel bounds on any hypothetical fifth force and millicharged particles (mCPs), as well as on the scale of inflation and on the effective Higgs quartic interaction. In particular, we find that combining the FLC with inflation leads to stronger bounds on mCPs than what the simple application of the FL

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The United Nations and European Union have set ambitious conservation goals to halt and reverse declines in biodiversity by protecting 30% of land and sea areas by 2030. Effective conservation planning requires evidence-based spatial prioritization to maximize the coverage of species within designated protected areas. Based on a pan-European database for occurrence and abundance of breeding birds

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Pancreatic islets of Langerhans are central to the pathogenesis of all major forms of diabetes. The ability to study human islets ex vivo has advanced our understanding of diabetes and aided in the development of novel therapeutics. However, for decades, very few laboratories had access to this critical resource and experiments on human islets were typically underpowered. More recently, multiple c

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Damselflies (Odonata: Zygoptera) have evolved highly developed visual systems for mate recognition, flight and prey detection. Wing Interference Patterns (WIPs), which are colors generated by thin-film interference in the wing membrane, could function as visual signals and play a role in sexual selection. Because the color of these signals depends on membrane thickness, a potential conflict exists

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For more than a decade, stem cells have been on the horizon as a future treatment for Parkinson's disease (PD) and with this vision, it is anticipated that this novel treatment approach may be a paradigm shift in treating PD. The field has progressed enormously during the past few years and several clinical phase I/IIa trials using human embryonic stem cells or induced pluripotent stem cells as so

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One characteristic trait of populism is its dramatic rhetoric onthemes such as the survival of the European people. This is particularlypresent in a cluster of conspiracy theories, in this article discussed un-der the collective term le grand remplacement, forming a cornerstoneof much right-wing populist rhetoric. In this article, it is suggested thatthe notion of “apocalyptic imaginaries” is a heOne characteristic trait of populism is its dramatic rhetoric on themes such as the survival of the European people. This is particularly present in a cluster of conspiracy theories, in this article discussed under the collective term le grand remplacement, forming a cornerstone of much right-wing populist rhetoric. In this article, it is suggested that the notion of “apocalyptic imaginaries” is a

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We present a method for obtaining an initial-state parton shower model where the (backward) evolution is fully consistent with the (forward) evolution of the collinear parton density is used. As a proof-of-concept we use parton densities obtained with the Parton Branching (PB) approach, and modify the default initial-state shower in PYTHIA8 with this method for consistency. PB is ideally suited fo

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This paper examines how transnational conservative religious networks (TCRNs) have cemented their position as major players in the Organization of American States (OAS) in order to dispute reproductive rights and rights relating to sexual diversity. Drawing on fieldwork, interviews and legal analysis in general assemblies and summits of the Americas (2020-2025), it identifies three main strategies

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Objectives: This study aimed to explore the stakeholder perspectives in a public–private partnership project as a remarkable initiative to enhance quality education at the tertiary level in Turkey. In this regard, the motivations behind participating in the partnership, perceived benefits and challenges, significant outcomes, and recommendations for similar prospective partnership programs were in

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PURPOSE: The aim of this study was to establish reference values for swallowing safety using flexible endoscopic evaluation of swallowing (FEES) in healthy adults across the lifespan and to examine the influence of age, sex, bolus characteristics, and snoring on the risk of unsafe swallowing.METHOD: A prospective cross-sectional study was conducted with 128 healthy adults (21-91 years). Participan

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Top-down approaches using inverse modelling provide valuable complementary information to national methane emission inventories, which are primarily based on bottom-up methods. Here, we focus on Italy, where methane is currently monitored at five stations that belong to the Integrated Carbon Observation System (ICOS). Top-down estimates show substantial discrepancies over this country, suggesting

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A3BX6 perovskites, a family of vacancy-ordered structures, exhibit diverse luminescence behaviors upon photon, electron, and high-energy excitation, primarily originating from intrinsic self-trapped excitons or dopant-induced electronic transitions. Upon B-site cation engineering, ns2 cations tune intrinsic luminescence, whereas transition-metal and rare-earth dopants activate characteristic d–d,

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Genome-wide association studies (GWAS) have revealed extensive polygenic signals and overlapping genetic architectures across human traits, creating a need for resources that connect trait-level genetic relationships with gene-level functional evidence. Here, we developed the Multi-Omics Causal Resource Database (MOCR-DB), an interactive platform that integrates large-scale GWAS summary statistics

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We explore three examples of teaching-development activities that aim to promote discussions about teaching among academic staff across several Norwegian Earth System Science departments. The three events are a conference-like annual gathering of students and staff from across the country, a monthly Teaching and Learning themed Journal Club held at a large department with a wide range of research