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Glucagon-like peptide-1 (GLP-1) receptor agonists are established pharmaceutical therapies for the treatment of type 2 diabetes and obesity. They mimic the action of GLP-1 to reduce glucose levels through stimulation of insulin secretion and inhibition of glucagon secretion. They also reduce body weight by inducing satiety through central actions. The GLP-1 receptor agonists used clinically are ba

Type 2 diabetes and dementia are associated, but it is unclear whether the two diseases have common genetic risk markers that could partly explain their association. It is also unclear whether the association between the two diseases is of a causal nature. Furthermore, few studies on diabetes and dementia have validated dementia end-points with high diagnostic precision. We tested associations bet

City marketing and convention bureaus value propositions in the post-covid timeThe role of convention bureaus across the world is to market destinations and cities.This paper explores destination marketing in the post pandemic time. It focusses on thevalues that convention bureaus, a key actor in the meetings industry, propose topotential visitors. The concept of value propositions (VPs) is common

In this paper, model-based sustainability assessment framework with social impact considerations is developed. The framework integrates the stochastic, nonlinear, and complex interrelationships that characterize most manufacturing systems, and incorporates their impact in the sustainability assessment module. The framework consists of three models that run successively, namely: stochastic discrete

Pteropodidae is the only phytophagous bat family that predominantly depends on visual and olfactory cues for orientation and foraging. During daytime, pteropodids of different species roost in sites with varying light exposure. Pteropodids have larger eyes relative to body size than insectivorous bats. Retinal topography has been studied in less than 10% of the approximately 200 pteropodid species

Any ultrafast optical spectroscopy experiment is usually accompanied by the necessary routine of ultrashort-pulse characterization. The majority of pulse characterization approaches solve either a one-dimensional (e.g., via interferometry) or a two-dimensional (e.g., via frequency-resolved measurements) problem. Solution of the two-dimensional pulse-retrieval problem is generally more consistent d

In research on intimate partner violence, most studies focus on those who are abused. In this chapter, we focus on how families, friends, relatives, and employers of abuse victims interact through the use of smartphones, social media platforms, apps, and other internet-connected devices. We discuss how digital technology is integrated into the lives of domestic abuse victims and their social netwo

Thermodynamic stability is a crucial fitness constraint in protein evolution and is a central factor in shaping the sequence landscapes of proteins. The correlation between stability and molecular fitness depends on the mechanism that relates the biophysical property with biological function. In the simplest case, stability and fitness are related by the amount of folded protein. However, when pro

BACKGROUND: Octylisothiazolinone is a biocide that has been reported as a moderate, but rare contact allergen.OBJECTIVES: To investigate the occurrence of octylisothiazolinone contact allergy and allergic contact dermatitis diagnosed and registered in the Allergen Bank at Odense University Hospital during the past 20 years. Octylisothiazolinone has been used for targeted testing only.METHOD: All o