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Apolipoprotein A-I in glucose metabolism and amyloidosis

The role of Apolipoprotein A-I (ApoA-I), the main protein component of HDL, in cholesterol transport and metabolism is well known and has been studied for more than four decades. More recently, ApoA-I protein has been shown to also have a positive role in glucose control by both stimulation of glucose uptake by muscles and by increasing glucose-stimulated pancreatic insulin secretion. Two of the f

The Challenges of Assurance on Non-financial Reporting

The purpose of this paper is to enhance our understanding of the notions and conceptual foundations of assurance in the standard setting arena. This will facilitate an informed discussion of the challenges and the role of assurance within an increasingly complex and fragmented corporate reporting regulatory landscape. The study draws on relevant literature on sustainability assurance and an analys

The Crisis of Care - Caring Against Crisis : Professional Responses to Austerity Politics in Female Dominated Welfare Professions

Capitalist crises, such as the current financial crisis, are also crises in the sphere of social reproduction, according to Fraser (2014). In the current phase of financialized capitalism, social reproduction is increasingly treated as a commodity. As many feminist- and gender scholars have showed, this has resulted in increased pressures on women’s labour. During the last ten years, the Nordic co

The rise of Integrated Reporting in the Public Sector : An analysis of transnational governance interactions

Integrated Reporting (IR) in the public sector has been put forward as a framework to help public sector entities address diverse accountability requirements while gaining a greater understanding of the ways in which they create value. This chapter has a strong focus on understanding the emergence of IR in the public sector through a multi-stakeholder approach and a governance perspective. The cha

Improving the quality of healthcare through interdisciplinary education - a collaboration between Medicine and Gender Studies

While Gender studies has sometimes been placed in opposition to biomedicine and medical practices in public debate, there is increasing scholarly recognition of the relevance of social factors and relationships for biological and medical phenomena and for the quality and equity of healthcare practices. In Sweden and internationally, medical schools have identified the need to integrate approaches While Gender studies has sometimes been placed in opposition to biomedicine and medical practices in public debate, there is increasing scholarly recognition of the relevance of social factors and relationships for biological and medical phenomena and for the quality and equity of healthcare practices (Chin et al., 2016; Meloni, Cromby, Fitzgerald, & Lloyd, 2018; SKL, 2014). In Sweden and int

Scheduling conflicts in the low-wage labor force: the case of Swedish and US women

By comparing the work-hours-related experiences of women in two countries that differ in their labor protections and their social-service provision—in other words, that differ in the extent to which neoliberalism holds sway—this manuscript sheds light on the implications of neoliberalism in terms of women’s working conditions.Specifically, we analyze the protections offered by each country that co

Recurrant collection of Drosophila melanogaster from wild African environments and genomic insights into species history

A long-standing enigma concerns the geographic and ecological origins of the intensively studied vinegar fly, Drosophilamelanogaster. This globally distributed human commensal is thought to originate from sub-Saharan Africa, yet untilrecently, it had never been reported from undisturbed wilderness environments that could reflect its precommensalniche. Here, we document the collection of 288 D. mel

Simultaneous X-ray Video-Fluoroscopy and Pulsed Ultrasound Velocimetry Analyses of the Pharyngeal Phase of Swallowing of Boluses with Different Rheological Properties

The Ultrasound Velocity Profiling (UVP) technique allows real-time, non-invasive flow mapping of a fluid along a 1D-measuring line. This study explores the possibility of using the UVP technique and X-ray video-fluoroscopy (XVF) to elucidate the deglutition process with the focus on bolus rheology. By positioning the UVP probe so that the pulsed ultrasonic beam passes behind the air-filled trachea

Health-related quality of life among tonsillar carcinoma patients in Sweden in relation to treatment and comparison with quality of life among the population

Background: The health-related quality of life (HRQOL) of tonsillar carcinoma survivors was explored to investigate any HRQOL differences associated with tumor stage and treatment. The survivors' HRQOL was also compared to reference scores from the population. Methods: In this exploratory cross-sectional study patients were invited 15 months after their diagnosis and asked to answer two quality of

Relaxor behavior and electrothermal properties of Sn- And Nb-modified (Ba,Ca)TiO3 Pb-free ferroelectric

Relaxor ferroelectrics have drawn attention for possible applications in solid-state cooling and thermal energy harvesting, owing to their electrothermal energy conversion properties. Here, we have synthesized and characterized the structure-property correlations of a new Sn- and Nb-doped (Ba,Ca)TiO3 relaxor ferroelectric with large pyroelectric and electrocaloric effects over a broad temperature

Invasive haemodynamics in de novo everolimus vs. calcineurin inhibitor heart transplant recipients

Aims: Invasive haemodynamic profiles at rest and during exercise after heart transplantation (HTx) have never been described in a randomized trial where de novo everolimus (EVR)-based therapy with early calcineurin inhibitor (CNI) withdrawal has been compared with conventional CNI treatment. We report central invasive haemodynamic parameters at rest and exercise during a 3 year follow-up after HTx

Identification of MUC5B, MUC5AC and small amounts of MUC2 mucins in cystic fibrosis airway secretions

To investigate the genetic identities of the mucins secreted in cystic fibrosis (CF) airways, sputum was collected from five individuals. Samples were separated into gel and sol phases by high-speed centrifugation and the gel phase was extracted in 6 M guanidinium chloride. The 'insoluble' residue remaining after extraction of the gel phase was brought into solution by reduction/alkylation. Densit

Mucin biosynthesis and secretion in tracheal epithelial cells in primary culture

Density-gradient centrifugation of bovine tracheal epithelial cell extracts revealed a 'high-density' (1.48 g/ml) sialic-acid-rich population as well as a 'low-density' (1.42 g/ml) one that reacted more strongly with a periodate-Schiff (PAS) assay. The sialic-acid-rich mucins were oligomeric molecules containing disulphide-bond-linked subunits and large glycosylated domains, whereas the PAS-reacti

Biosynthesis of mucins in bovine trachea : identification of the major radiolabelled species

Bovine trachea in organ culture secretes mucus containing a 'high-density' (1.46 g/ml) and a 'low-density' (1.37 g/ml) mucin similar to those identified previously in bovine respiratory secretions [Hovenberg, Carlstedt and Davies (1997) Biochem. J. 321, 117-123]. After pulse-labelling, autoradiography showed uptake of [35S]sulphate by both epithelial goblet cells and submucosal glands, while [3H]p