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The mitochondrial protein NAD(P) + transhydrogenase (NNT) has been implicated in the metabolic derangements observed in obesity. Mice with the C57BL/6J genetic background bear a spontaneous mutation in the Nnt gene and are known to exhibit increased susceptibility to diet-induced metabolic disorders. Most of the studies on NNT in the context of diet-induced obesity have compared C57BL/6J mice with

A common and huge challenge in risk and disaster management such as urban flood is the lack of effective communication, especially instant communication from the general public when sudden flooding occurs. There is a strong need to facilitate complementary risk management for authorities to communication with public in addition to mainstream channels. In a recent international project, possibility

To investigate whether coronary artery disease (CAD) burden is associated with plasma levels of the myocardial biomarkers Troponin I (TropI) and NT-proBNP in a large population-based sample using a cross-sectional design. Coronary computerized tomography (CT) angiography was performed in 25,859 subjects without a history of atherosclerotic disease from SCAPIS study (age 50-65, 52% women). TropI an

Gestational diabetes mellitus (GDM) is a prevalent pregnancy complication that seriously endangers maternal and infant health, posing a medical and economic burden worldwide. Several dietary patterns have been recommended for women of childbearing age, demonstrating a positive role in preventing and managing GDM. However, these dietary patterns may not fully take environmental factors into account

This paper investigates the confluence of artificial intelligence (AI), the performing arts, and emotion communication, focusing on how generative AI and social robotics – today’s forefront disruptive technologies – can facilitate an exploration of emotional dynamics across artistic mediums. Drawing on the intermedial and multimodal capacities of opera, this paper presents AI-enhanced opera as a p

Introduction/objectivesInfective endocarditis (IE) caused by non-HACEK Gram-negative bacteria (nHGNB) is uncommon. In the 2023 Duke-ISCVID diagnostic criteria, Pseudomonas aeruginosa and Serratia marcescens were added as “typical” pathogens. We examine the consequences of this addition, the risk of IE in bacteremia from nHGNB species and the features of IE caused by nHGNB.Materials and methodsnHGN

Aims/hypothesisObservational studies indicate that type 2 diabetes mellitus and fasting glucose levels are associated with a greater risk for hip fracture, smaller bone area and higher bone mineral density (BMD). However, these findings may be biased by residual confounding and reverse causation. Mendelian randomisation (MR) utilises genetic variants as instruments for exposures in an attempt to a

Challenges the terrestrial focus of European prehistory, emphasizing the significance of seascapes, maritime networks, and coastal societies in shaping prehistoric Europe.For many years now, the main thrust of European prehistory has followed a fundamentally terrestrial plot line. This terrestrial paradigm has undervalued the story of Europe as a peninsula between the Baltic, Mediterranean and Atl

Emotional communication, especially through social media platforms, has become a contemporary populist threat. While this phenomenon has been studied in for example news media and social movements, we know less about its influence on civil society organizations, despite their pluralism being a centerpiece in a vibrant democracy. More specifically, we do not know if social media make civil society

Background: Electroconvulsive therapy (ECT) is an effective treatment for depression with potential transient cognitive side effects. However, subjective memory impairment can extend over a long period after ECT. Objectives: This study aimed to assess potential risk factors for long-term subjective memory impairment 6 months after ECT and to explore if the associations are mediated by depressive s

Purpose: To investigate long-term chronic postoperative inguinal pain (CPIP), QoL and recurrence in patients with a primary inguinal hernia comparing TEP to Lichtenstein. Material and methods: A questionnaire-based follow-up containing the Inguinal Pain Questionnaire (IPQ), the Cunningham Pain Scale and SF-36 was done 8 years after the TEPLICH RCT. The main objective was non-ignorable pain last we

Type 1 diabetes (T1D) involves the interaction of multiple gene variants, environmental factors, and immunoregulatory dysfunction. Major T1D genetic risk loci encode HLA-DR and -DQ. Genetic heterogeneity and linkage disequilibrium in the highly polymorphic HLA region confound attempts to identify additional T1D susceptibility loci. To minimize HLA heterogeneity, T1D patients (N = 365) and control

INTRODUCTION: Central venous catheterisation is a common procedure in intensive care therapy and the use of central venous catheters is essential for treatment of many medical disorders. Although rare, central venous catheterisation is associated with mechanical complications that can be life-threatening if untreated. Real-time ultrasound guidance reduces the incidence of mechanical complications

Supplemental Instruction (SI) is today a well-known academic support model to address retention and student performance in higher education. However, in studies reporting the effect of SI, the number of attendees at SI-sessions are seldom mentioned or reflected upon.This study investigates if there is a lower, optimal, and upper number of SI-attendees for SI-sessions with viable learning condition