Primary Sjogren's syndrome (SS) is a systemic autoimmune inflammatory disease characterized by focal lymphocytic infiltrates in the lachrymal and salivary glands and autoantibodies against the SSA/Ro and SSB/La antigens. Experimental studies have shown an activation of NF-B in primary SS. NF-B activation results in inflammation and autoimmunity and is regulated by inhibitory and activating protein

Gene-lifestyle interactions have been suggested to contribute to the development of type 2 diabetes. Glucose levels 2 h after a standard 75-g glucose challenge are used to diagnose diabetes and are associated with both genetic and lifestyle factors. However, whether these factors interact to determine 2-h glucose levels is unknown. We meta-analyzed single nucleotide polymorphism (SNP) X BMI and SN

OBJECTIVE-To develop a model for the prediction of type 2 diabetes mellitus (T2DM) risk on the basis of a multivariate logistic model and 1-h plasma glucose concentration (1-h PG). RESEARCH DESIGN AND METHODS-The model was developed in a cohort of 1,562 non-diabetic subjects from the San Antonio Heart Study (SAHS) and validated in 2,395 nondiabetic subjects in the Botnia Study. A risk score on the

OBJECTIVE: To describe the frequency of symptoms and associated conditions among screening-detected celiac disease (CD) cases and non-CD children and to evaluate questionnaire-based case-finding targeting the general population. METHODS: In a population-based CD screening of 12-year-olds, children and their parents completed questionnaires on CD-associated symptoms and conditions before knowledge

Background and purpose The Scandinavian Sarcoma Group (SSG) XIV protocol was based upon the organisations experience from 3 previous osteosarcoma trials and was considered best standard of care for patients with extremity localised, non-metastatic osteosarcoma. We report the outcome of this protocol. Patients and methods From March 2001 to April 2005, 63 patients recruited from 10 centres in Finla

OBJECTIVE Patients with latent autoimmune diabetes in adults (LADA) express autoantibodies against the 65-kDa isoform of GAD (GADA). Intervention with recombinant human GAD65 formulated with aluminium hydroxide (GAD-alum) given twice subcutaneously to LADA patients at intervals of 4 weeks was safe and did not compromise beta-cell function in a Phase II clinical trial. GADA affinity has been shown

Syftet med denna uppsats är att undersöka tillståndet i Köphultssjön i södra Småland och vilken påverkan omgivningen har på sjön. Sjön är drabbad av försurning och orsaker till och effekter av försurning undersöks. Eftersom sjön kalkas, studeras vilka effekter detta kan ha på sjön. Det har konstaterats att ett vassbälte breder ut sig i sjön och därför undersöks vilka orsaker som kan finnas till de

How many times have you heard that if children are in church they should be quiet and still? It was common to hear when I was young that children should go out as soon as they started making any noise. It was and is always a pleasure for everyone to hear the cute children singing a pretty song in church but afterwards there should be silence again! What I want is for the congregation to accept the

Virtual meetings and virtual collaboration technologies are applications where ICT could potentially be used to green business activities. There are, however, uncertainties and disagreements about the organisational effects of increased use of these technologies, which makes it difficult to measure and follow up on outcomes. This thesis explores the potential effects that virtual meetings and vir

Urbaniseringen sker idag i snabb takt, men genom bebyggelseförtätning kan städernas utbredningshastighet avta. Behovet av att förtäta medför dock att urbana grönytor riskerar att få låg prioritet i stadsplaneringen om inte deras värden är tillräckligt tydliga. Syftet med denna studie är att tydliggöra värdet på de urbana grönytorna i Lunds kommun, samt att visa på potentialen att höja detta värde.Urbanization is a major driver of land-use change but the urban sprawl can be decreased by the densification of cities. On the other hand densification poses a threat to the urban green spaces; areas that have a high delivery of ecosystem services are essential to a high-quality living environment. The aim of this thesis is to illuminate the benefits of urban green space to raise their importance

När en kvinna föder barn kan hon få skador i underlivet. Det kan göra att man senare behöver opereras för att t.ex. tarmen eller urinblåsan inte sitter helt fast på sin ursprungliga plats i magen utan istället buktar ut i slidan, något som kallas för framfall. Ca 7000 kvinnor opereras för sådana problem varje år i Sverige och det blir en stor kostnad för samhället. Även om man kan få framfall utan

Abstract Authors: Lisabeth Carlqvist & Malin Mauritsson Title: “Straight guys: dare trying taking it up the butt” – An analysis of sexual normality portrayed on Ligga med P3’s website. [Translated title] Supervisor: Annika Capelán Assessor: Eva Johnsson The aim of this study was to provide a closer look at how sexual normality is portrayed on the internet, focusing on a particular website ch

Recent discussions about a stolen cultural heritage have resulted in several repatriation claims from indigenous people. These claims are often considered a way to disengage from a coloni-al past. There are numerous conventions and ethical guidelines about repatriation to consider; nevertheless repatriation cases are being handled in different ways across the globe. In 2004 the Jewish congregation

Uppsatsens titel: Vilka faktorer påverkar möjligheterna att använda Yield Management? - En komparativ fallstudie mellan den svenska flyg- och fotbollsbranschen. Seminariedatum: 2012-05-29 Ämne/kurs: FEKN90 - Företagsekonomi: Examensarbete på civilekonomprogrammet Författare: Henrik Agardh & Jonathan Lindwert Handledare: Niklas Hallberg Nyckelord: Dynamiska prissättningsstrategier, Marknadsacce

I södra Kanada finns ett område med mängder av unikt välbevarade fossil från silurperioden (444-416 miljoner år sedan). I berglager från det så kallade Eramosaområdet har nu omkring 425 miljoner år gamla fossila rester efter havsborstmaskar hittats. Eftersom dessa djur består av mjuka vävnader som snabbt bryts ner efter döden så är det framför allt deras käkar, eller scolecodonter, som bevaras somThe Silurian Eramosa Lagerstätte in Ontario, Canada, is represented by three distinguished biotas (1 to 3) with exceptionally well preserved fossils. In this study, the jawed polychaete fauna is described and discussed for the first time, on the basis of scolecodonts and jaw apparatuses, recovered from Biota 1 and 3. One new paulinitid species, Kettnerites sp. a, is described from a wealthy collec

Popular science General introduction Two main activities take place into forests: photosynthesis, or GPP (the uptake of CO2 by plants, which leads to their growth) and respiration (the release of CO2 by those plants). The Net Ecosystem Exchange NEE is the difference between photosynthesis and respiration, and it depends on the nature of the forests and on climate particularities. With the ongoing This study shows how six different European forests react during the summer to abnormally warm temperatures, from 1996 to 2006. With the forecasted increase of summer temperatures over Europe, the carbon balance of forests – photosynthesis (GPP), ecosystem respiration and Net Ecosystem Exchange - in likely to change. In this thesis, the photosynthesis and the respiration of six European forests w

Ett första steg i arbetet att uppskatta kolflödet mellan landbaserade ekosystem och atmosfären är att så precist som möjligt analysera kvantiteten ovanjordisk biomassa. LiDAR teknologi har i detta avseende visat sig vara ett värdefullt verktyg. Det överlöpande målet med denna studie är att utveckla en förenklad metod, baserad på fjärranalys, för att uppskatta ovanjordisk biomassa för individuella As a first step in the assessment of carbon flux between the terrestrial environment and the atmosphere it is important to accurately quantify the carbon stock of forest ecosystems. LiDAR technology, in this respect, has proved to be a valuable tool, able to provide accurate estimates of aboveground biomass (AGB). The overall goal of this study was to develop a simplified method for assessing AGB