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The current state of the water and sanitation sector has put water­related innovations high on the global policy agenda. However, the systemic complexity that typically surrounds such contexts call for actionable knowledge of how to enable and orchestrate innovative solutions by connecting different players via organized networks. In this study we explore and analyse the Water Innovation AcceleratThe current state of the water and sanitation sector has put water-related innovations high on the global policy agenda. However, the systemic complexity that typically surrounds such contexts call for actionable knowledge of how to enable and orchestrate innovative solutions by connecting different players via organized networks. In this study we explore and analyse the Water Innovation Accelerat

Conclusion: The data indicate important roles for phosphodiesterase (PDE) 3, 4, 5, and related cAMP and cGMP pools in the regulation of inner ear fluid homeostasis. Thus, dysfunction of these enzymes might contribute to pathologies of the inner ear. Objective: The mechanisms underlying endolymphatic hydrops, a hallmark of inner ear dysfunction, are not known in detail; however, altered balance in

Background and Objectives: Genome-wide association studies (GWAS) have identified several genetic regions involved in immune-regulatory mechanisms to be associated with celiac disease. Previous GWAS also revealed an over-representation of genes involved in type 2 diabetes and anorexia nervosa associated with celiac disease, suggesting involvement of common metabolic pathways for development of the

ABSTRACT: In the light of the observed and projected regional warming trend in northern Europe, new recommendations are needed for climate-proofing the selection of forest trees seedlings and growth estimates. Drawing on recently developed climate data sets, both observations of the recent past, and scenarios for the future we present and analyse a set of climate indices tailored to be used for op

The ambition to make all kinds of societal services, public as well as commercial ones, more effective and accessible via online applications is reoccurring all over the western world. To a large extent, such ambitions hold the promise to make citizens’ everyday lives easier, but they are, however, also problematic in that they presuppose a number of important prerequisites. They presuppose widesp

The avian haemosporidian parasite Haemoproteus majoris has been reported to infect a wide range of passerine birds throughout the Holarctic ecozone. Five cytochrome b (cyt b) lineages have been described as belonging to the morphological species H. majoris, and these form a tight phylogenetic cluster together with 13 undescribed lineages that differ from each other by < 1.2% in sequence divergence

Over the past few years, a growing body of work in economic geography and innovation studies has enhanced our understanding of forms and determinants of regional industrial path development. The importance of policy, however, has received limited attention and accordingly, the role of policy for the emergence and development of new regional industrial growth paths remains largely unexplored. This

Today, commercially used brasses commonly contain 2 to 4 wt.% lead. As the availability of low-lead and lead-freebrass increase, there are environmental incentives for investigating the consequences of replacing thelead-containing brasses with lead-free equivalents. Generally, lead-free brass is expected to have a lowermachinability than its lead-alloyed counterpart, implying a higher manufacturin

Aerosol particles exist in the atmosphere in large concentrations and have significant global climate effects. New particle formation is an aerosol particle source and, to date, its contribution to the total aerosol concentration in the atmosphere is not fully understood. This study focuses on the extension of new particle formation events that begin in Lille Valby, Denmark and travel over 70 km t

As part of a long-term project investigating the relevance of phenomenology for (cognitive) linguistics we analyse two central, interrelated concepts: embodied intersubjectivity (intercorporeality) and sedimentation. With respect to the first, we spell out a number of different intercorporeal structures, emanating at the most fundamental level from the dual Leibkörper nature of the body. Further,

The effect molecular crowding, defined as the volume exclusion exerted by one soluble inert molecule upon another soluble molecule, has on the structure and self-interaction of lipid-free apoA-I were explored. The influence of molecular crowding on lipid-free apoA-I oligomerization and internal dynamics has been analyzed using electron paramagnetic resonance (EPR) spectroscopy measurements of nitr

Type 2 diabetes and skeletal muscle insulin resistance have been linked to accumulation of the intramyocellular lipid-intermediate diacylglycerol (DAG). However, recent animal and human studies have questioned such an association. Given that DAG appears in different stereoisomers and has different reactivity in vitro, we investigated whether the described function of DAGs as mediators of lipid-ind

Genome-wide association studies (GWAS) have found few common variants that influence fasting measures of insulin sensitivity. We hypothesized that a GWAS of an integrated assessment of fasting and dynamic measures of insulin sensitivity would detect novel common variants. We performed a GWAS of the modified Stumvoll Insulin Sensitivity Index (ISI) within the Meta-Analyses of Glucose and Insulin-Re

BACKGROUND: More knowledge about how recovery may promote health among parents with small children is needed.OBJECTIVE: To explore whether insufficient time for leisure was associated with poorer perceived health and higher stress in working parents. A further aim was to explore potential gender differences in the association between insufficient time for leisure and poor perceived health.METHODS:

The value of course evaluations has been debated since they frequently fail to capture the complexity of education and learning. Group Concept Mapping (GCM), a participant-centred mixed-method was explored as a tool for evaluation and development in nursing education and to better understand students' learning experiences, using data from a GCM-based evaluation of a research training assignment in

BACKGROUND: Day centers have been criticized for giving attendees a lower social status because they only offer activities that are often work-like although not financially of benefit to attendees. OBJECTIVES: To explore day center attendees' perceived social status and to identify associations among the attendees with the center's orientation with activity, well-being, and psychiatric symptoms. M

Intervention with Mediterranean diet (MedDiet) has provided a high level of evidence in primary prevention of cardiovascular events. Besides enhancing protection from classical risk factors, an improvement has also been described in a number of non-classical ones. Benefits have been reported on biomarkers of oxidation, inflammation, cellular adhesion, adipokine production, and pro-thrombotic state

RNA editing is a post-transcriptional alteration of RNA sequences that, via insertions, deletions or base substitutions, can affect protein structure as well as RNA and protein expression. Recently, it has been suggested that RNA editing may be more frequent than previously thought. A great impediment, however, to a deeper understanding of this process is the paramount sequencing effort that needs