Search results

Using genome-wide association, we identify common variants at 2p12-p13, 6q26, 17q23 and 19q13 associated with serum creatinine, a marker of kidney function (P = 10(-10) to 10(-15)). Of these, rs10206899 (near NAT8, 2p12-p13) and rs4805834 (near SLC7A9, 19q13) were also associated with chronic kidney disease (P = 5.0 x 10(-5) and P = 3.6 x 10(-4), respectively). Our findings provide insight into me

The paediatric nasopharyngeal flora is regarded as the largest reservoir for Streptococcus pneumoniae, and the carrier state is always antecedent to infection and a prerequisite for dispersion of these bacteria. Pneumococci are the predominant aetiology of bacterial respiratory tract infections and a major cause of morbidity and mortality, in the most severe cases due to invasive pneumococcal dise

Today type 2 diabetes is a common disease with a worldwide prevalence of 8.3%. The disease is characterised by hyperglycaemia which is a result of insufficient insulin secretion from the beta-cells in the pancreatic islets as well as an insulin resistance seen in the target tissues. Type 2 diabetes is a multifactorial disease with genetic, epigenetic and environmental background. In study I we in

Resisters in Conversation is one of a series of booklets that present conversations and reflections on feminist issues within a trans-European academic context. Each is written by a different group of academics from across Europe. They have one thing in common: a passionate interest in teaching and feminist politics. Building on this, the authors address specific issues generated by the national a

This textbook aims to provide a comprehensible introduction to Engineering Hydrology for environmental engineering students. The book comprises of 8 chapters which provide a holistic view of hydrology, seen as the water transport in nature with human influence, and deal with the main hydrological systems and processes. Each chapter ends with a few engineering examples together with a discussion of

The study of residences at central places from the Late Iron Age in Scandinavia has mainly been aimed at identifying buildings of exceptional size or function. However, until recently the archaeological situation has not been detailed enough to study the sequence of a residence for several centuries and with internal changes related to internal or external factors. New excavation results from Uppå

Many passerines migrate during the night and at high altitudes, making their migration difficult to observe. By using tracking radars we have been able to make exact observations of the flight behaviour of passerines on nocturnal migration, which has enabled us to test several hypotheses about adaptive values and constraints regarding migratory behaviour in different ecological contexts. We have i

New institutional theory has been critizised, for describing institutionalization as a static qualitative state rather than a process. In this paper we provide an extended understanding of the process of institutionalization by replacing the mechanical concept of diffusion by the concept of translation and an analytical model of "trevel of ideas". Analyzing the field material from three cases of t