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Non-invasive biomarkers for androgen receptor (AR) pathway activation are urgently needed to better monitor patient response to prostate cancer (PCa) therapies. AR is a critical driver and mediator of resistance of PCa but currently available non-invasive PCa biomarkers to monitor AR activity are discordant with downstream AR pathway activity. External beam radiotherapy (EBRT) remains a common tre

Recent studies highlight the importance of lipotoxic damage in aortic cells as the major pathogenetic contributor to atherosclerotic disease. Since the STE20-type kinase STK25 has been shown to exacerbate ectopic lipid storage and associated cell injury in several metabolic organs, we here investigate its role in the main cell types of vasculature. We depleted STK25 by small interfering RNA in hum

BackgroundNon-coding genetic variants that influence gene transcription in pancreatic islets play a major role in the susceptibility to type 2 diabetes (T2D), and likely also contribute to type 1 diabetes (T1D) risk. For many loci, however, the mechanisms through which non-coding variants influence diabetes susceptibility are unknown.ResultsWe examine splicing QTLs (sQTLs) in pancreatic islets fro

Hydrogenated vegetable oil (HVO) is a renewable diesel fuel used to replace petroleum diesel. The organic compounds in HVO are poorly characterized; therefore, toxicological properties could be different from petroleum diesel exhaust. The aim of this study was to evaluate the exposure and effective biomarkers in 18 individuals after short-term (3 h) exposure to HVO exhaust and petroleum diesel exh

PURPOSE: Despite impressive response rates following adoptive transfer of autologous tumor-infiltrating lymphocytes (TILs) in patients with metastatic melanoma, improvement is needed to increase the efficacy and broaden the applicability of this treatment. We evaluated the use of vemurafenib, a small-molecule BRAF inhibitor with immunomodulatory properties, as priming before TIL harvest and adopti

A quarter of ischaemic strokes are lacunar subtype, typically neurologically mild, usually resulting from intrinsic cerebral small vessel pathology, with risk factor profiles and outcome rates differing from other stroke subtypes. This European Stroke Organisation (ESO) guideline provides evidence-based recommendations to assist with clinical decisions about management of lacunar ischaemic stroke

Human blood plasma can be obtained relatively noninvasively and contains proteins from most, if not all, tissues of the body. Therefore, an extensive, quantitative catalog of plasma proteins is an important starting point for the discovery of disease biomarkers. In 2005, we showed that different proteomics measurements using different sample preparation and analysis techniques identify significant

Antibodies play a key role in acquired human immunity to Plasmodium falciparum (Pf) malaria and target merozoites to reduce or prevent blood-stage replication and the development of disease. Merozoites present a complex array of antigens to the immune system, and currently, there is only a partial understanding of the targets of protective antibodies and how responses to different antigens are acq

Quantitative data are needed to constrain the feedback loops between vegetation and hydroclimate. In this study, the amplitudes of variations in the triple oxygen isotope composition of water at the soil-plant-atmosphere interface are measured in savanna and dry forest contexts in West Africa (Benin and Senegal). Comparison of in situ data and model estimates reveals the following: (a) The value o

Postadress: Box 882, 251 08 Helsingborg Besöksadress: Universitetsplatsen 2, Helsingborg Telefon: 0709-565793, 046-222 00 00 E-post: jerker.jacobsson@ch.lu.se Webbadress: www.ch.lu.se Utveck l ingsenheten Campus Hels ingborg Jerker Jacobsson , admin is t ra t iv chef Kris- och beredskapsplan för Campus Helsingborg Datum 2025-06-05 1 1 Diarienummer STYR V2025/1588 Kris- och beredskapsplan 2 Innehål

https://www.ch.lu.se/internt/sites/ch.lu.se.internt/files/2025-06/Kris-%20och%20beredskapsplan%20f%C3%B6r%20Campus%20Helsingborg%20rev%20250605.pdf - 2026-05-10

Postadress: Box 882, 251 08 Helsingborg Besöksadress: Universitetsplatsen 2, Helsingborg Telefon: 0709-565793, 046-222 00 00 E-post: jerker.jacobsson@ch.lu.se Webbadress: www.ch.lu.se Utveck l ingsenheten Campus Hels ingborg Jerker Jacobsson , admin is t ra t iv chef Kris- och beredskapsplan för Campus Helsingborg Datum 2025-08-25 1 1 Diarienummer STYR V2025/1588 Kris- och beredskapsplan 2 Innehål

https://www.ch.lu.se/internt/sites/ch.lu.se.internt/files/2025-08/Kris-%20och%20beredskapsplan%20f%C3%B6r%20Campus%20Helsingborg%20rev%20250825.pdf - 2026-05-10

Denna information är till för att underlätta arbetet med den avslutande terminens Självständiga arbete 2, även kallat Examensarbetet. I egenskap av reflekterande praktiker ska du efter genomgången kurs ha genomfört ett självständigt arbete där du undersöker valda aspekter av din kommande musikpedagogiska verksamhet. Studien ska ha redovisats i en forskningsrapport, kommuniceras vid en presentation

https://www.mhm.lu.se/internt/examensarbete - 2026-05-09

Universitetslektor Kontaktinformation E-post: martin [dot] andersson [at] ekh [dot] lu [dot] se Telefon: +46 46 222 44 85Organisation Ekonomisk-historiska institutionen Besöksadress: Scheelevägen 15 B, Lund Rumsnummer: Alfa 1:2042 Hämtställe: 10 WebbplatsMartin Anderssons profil i Lunds universitets forskningsportalAndra roller Universitetslektor Ekonomisk utveckling i det globala Syd Biträdande k

https://www.ehl.lu.se/martin-andersson - 2026-05-09

Lovisa Häckner PosseIntegrationskrav i domstol - En studie av hur svenska migrationsdomstolar förhåller sig till nationella politiska ambitioner och övernationella rättskällorDatum för disputationen: 2 majFakultetsopponent: Professor Gregor Noll,  Göteborgs universitet                             Ämne: Offentlig rättAbstractSamhällsintegration är en viktig del av dagens migrationskontrollsystem. D

https://www.jur.lu.se/forskning/disputationer/disputationer-2024 - 2026-05-09

Universitetslektor Kontaktinformation E-post: ullrika [dot] sahlin [at] mgeo [dot] lu [dot] seOrganisation Miljö- och geovetenskapliga institutionen (MGeo) Hämtställe: 16 WebbplatsUllrika Sahlins profil i Lunds universitets forskningsportalAndra roller Medlem i Strategiskt forskningsområde BECC: Biodiversity and Ecosystem services in a Changing Climate Medlem i Strategiskt forskningsområde MERGE:

https://www.cec.lu.se/sv/ullrika-sahlin - 2026-05-09

In recent years, it has become increasingly recognized that the traditional production-based methods for calculations of greenhouse gas emissions have shortcomings. This is justified by the fact that such inventories only include emissions that occur within a particular geographical area. As major emissions also arise as a result of imports of goods and services and from international travel, such

Extrema klimathändelser såsom torka, skyfall och extrema temperaturer förväntas bli mer frekventa som följd av klimatförändringar. Extrema klimathändelser kan potentiellt stressa och skada vegetation över stora områden och leda till förändring i kolcykel, vegetationsgrönhet, albedo samt ändrad artkomposition. Denna studie fokuserar på två typer av extrema klimathändelser; frystorkning orsakad av eWith climate change, the frequency in climate extremes such as drought, heavy rainfalls, and extreme temperatures is predicted to increase. These extremes can potentially stress and damage vegetation over large areas, leading to altered carbon cycle, vegetation greenness, albedo, and shifted species composition. This study focuses on two different types of extreme events; frost drought caused by w

Problem: Företag som är en del av en multinationell verksamhet kan råka ut för kriser som är en följd av en händelse som utspelat sig på långt geografiskt avstånd. Ett exempel på detta är energibolaget Enrons konkurs, som har kastat en skugga över hela revisionsvärlden. Enrons konkurs berodde bland annat på tveksamma bokföringsmetoder och till följd av detta har även deras revisorer ifrågasatts. R

In 2006, Professor Juliet Stumpf at the Lewis and Clark Law School in Portland, Oregon coined the term “crimmigration”. In doing so, she gave a name to a legal development that had evolved in the United States since the mid-1980s. The term is a concatenation of ”criminal” and ”immigration”; suitable considering the legal field describes and highlights the merger of criminal and immigration law. To

Den centrala frågan i denna framställning är huruvida det finns ett behov av förändring vad gäller livstidsstraffet i Sverige, och om frågan besvaras jakande, vad förändringen i så fall skulle bestå av. För att kunna besvara frågeställningen på ett tillfredställande sätt jämförs det svenska livstidsstraffet med de engelska och norska påföljdssystemen. Inledningsvis redogörs för olika bestraffningThe main point of this thesis is whether or not there is a need for modifications of the life sentence in Sweden, and should that be the case, how that modification is supposed to be constructed. To answer this in an adequate manner, the Swedish life sentence is going to be compared to the English and Norwegian equivalents. To start with, an account of different theories on penalization and princ