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Predictors of Rapid Aortic Root Dilation and Referral for Aortic Surgery in Marfan Syndrome

Few data exist regarding predictors of rapid aortic root dilation and referral for aortic surgery in Marfan syndrome (MFS). To identify independent predictors of the rate of aortic root (AoR) dilation and referral for aortic surgery, we investigated the data from the Pediatric Heart Network randomized trial of atenolol versus losartan in young patients with MFS. Data were analyzed from the echocar

Alteration of amino acid and biogenic amine metabolism in hepatobiliary cancers: Findings from a prospective cohort study.

Perturbations in levels of amino acids (AA) and their derivatives are observed in hepatocellular carcinoma (HCC). Yet, it is unclear whether these alterations precede or are a consequence of the disease, nor whether they pertain to anatomically related cancers of the intrahepatic bile duct (IHBC), and gallbladder and extrahepatic biliary tract (GBTC). Circulating standard AA, biogenic amines and h

CYP17 genetic variation and risk of breast and prostate cancer from the national Cancer Institute Breast and Prostate Cancer Cohort Consortium (BPC3)

CYP17 encodes cytochrome p450c17 alpha, which mediates activities essential for the production of sex steroids. Common germ line variation in the CYP17 gene has been related to inconsistent results in breast and prostate cancer, with most studies focusing on the nonsynonymous single nucleotide polymorphism (SNP) T27C (rs743572). We comprehensively characterized variation in CYP17 by direct sequenc

Reproductive and menstrual factors and risk of differentiated thyroid carcinoma: The EPIC study

Differentiated thyroid carcinoma (TC) is threefold more common in women than in men and, therefore, a role of female hormones in the etiology of differentiated TC has been suggested. We assessed these hypotheses in the European Prospective Investigation into Cancer and Nutrition (EPIC) cohort. Among 345,157 women (mean age 51) followed for an average of 11 years, 508 differentiated TC cases were i

High-risk melanoma susceptibility genes and pancreatic cancer, neural system tumors, and uveal melanoma across GenoMEL

GenoMEL, comprising major familial melanoma research groups from North America, Europe, Asia, and Australia has created the largest familial melanoma sample yet available to characterize mutations in the high-risk melanoma susceptibility genes CDKN2A/alternate reading frames (ARF), which encodes p16 and p14ARF, and CDK4 and to evaluate their relationship with pancreatic cancer (PC), neural system

Genome-wide association study identifies susceptibility loci for B-cell childhood acute lymphoblastic leukemia

Genome-wide association studies (GWAS) have advanced our understanding of susceptibility to B-cell precursor acute lymphoblastic leukemia (BCP-ALL); however, much of the heritable risk remains unidentified. Here, we perform a GWAS and conduct a meta-analysis with two existing GWAS, totaling 2442 cases and 14,609 controls. We identify risk loci for BCP-ALL at 8q24.21 (rs28665337, P = 3.86 × 10-9, o

Vitamin D Receptor Polymorphisms and Breast Cancer Risk: Results from the National Cancer Institute Breast and Prostate Cancer Cohort Consortium

Background: Vitamin D is hypothesized to lower the risk of breast cancer by inhibiting cell proliferation via the nuclear vitamin D receptor (VDR). Two common single nucleotide polymorphisms (SNP) in the VDR gene (VDR), rs154441.0 (BsmI), and rs2228570 (FokI), have been inconsistently associated with breast cancer risk. Increased risk has been reported for the FokIff genotype, which encodes a less

Multiplex genome editing eliminates lactate production without impacting growth rate in mammalian cells

The Warburg effect, which describes the fermentation of glucose to lactate even in the presence of oxygen, is ubiquitous in proliferative mammalian cells, including cancer cells, but poses challenges for biopharmaceutical production as lactate accumulation inhibits cell growth and protein production. Previous efforts to eliminate lactate production in cells for bioprocessing have failed as lactate

Developing rights-based standards for children having tests, treatments, examinations and interventions : using a collaborative, multi-phased, multi-method and multi-stakeholder approach to build consensus

Children continue to experience harm when undergoing clinical procedures despite increased evidence of the need to improve the provision of child-centred care. The international ISupport collaboration aimed to develop standards to outline and explain good procedural practice and the rights of children within the context of a clinical procedure. The rights-based standards for children undergoing te

Publications

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https://www.regenerative-neurobiology.lu.se/publications - 2025-08-01

107 09192019 679 107 MP213 Lee DMRR 2019

Nested case-control data analysis using weighted conditional logistic regression in The Environmental Determinants of Diabetes in the Young (TEDDY) study: A novel approach Received: 23 January 2019 Revised: 8 July 2019 Accepted: 11 July 2019 DOI: 10.1002/dmrr.3204 R E S E A R CH AR T I C L E Nested case‐control data analysis using weighted conditional logistic regression in The Environmental Deter

https://www.teddy.lu.se/sites/teddy.lu.se/files/2021-12/107%2009192019_679_107_MP213_Lee_DMRR_2019.pdf - 2025-08-02

progSIGWriting20

progSIGWriting20 Program version: 08-06-10, 6.20 SIG Writing 2008 Program PROGRAM OVERVIEW WEDNESDAY THURSDAY FRIDAY 8.00-9.30 Registration with coffee 8.30-9.00 Late registration 9.00-10.00 Paper sessions 9.30-10.15 Opening in Hörsalen/Auditorium 9.00-10.30 Paper sessions 10.00-10.30 Coffee in Entrance Hall 10.30-11.00 Coffee in Entrance Hall 10.30-12.30 Paper sessions 11.00-12.30 Paper sessions

https://konferens.ht.lu.se/fileadmin/conferenceFiles/sigwriting-2008/docs/progsigwriting.pdf - 2025-07-31

Martin Berggren

Professor Kontaktinformation E-post: martin [dot] berggren [at] nateko [dot] lu [dot] se Telefon: +46 46 222 17 34 Mobil: +46 73 092 61 98Organisation Institutionen för naturgeografi och ekosystemvetenskap Rumsnummer: 351 Hämtställe: 16 WebbplatsMartin Berggrens profil i Lunds universitets forskningsportalAndra roller Lärare Institutionen för naturgeografi och ekosystemvetenskap Principal Investig

https://www.nateko.lu.se/sv/martin-berggren - 2025-08-01

Pilotförsök för generell övervakning av pollinatörer – resultat för fältsäsongen 2021

Lunds universitet har på uppdrag av Naturvårdsverket under 2021 utvärderat metodik för nationell pollinatörsövervakning. Metodiken bygger på rapporten ”Proposal for an EU pollinator monitoring scheme” som tagits fram av en expertgrupp inom EU (Potts m. fl. 2020) och ska kunna ge underlag för uppföljning av pollinatörer på nationell nivå med ett främsta fokus på landskapet utanför områden som omfat

Foreskrifter for utbildning pa forskarniva vid lu

Brevmall Postadress box 117, 223 50 Lund Besöksadress Byrålogen, Paradisgatan 5 C Telefon 046-222 30 32 E-post cecilia.gagne@rektor.lu.se Rektor Föreskrifter för utbildning på forskarnivå vid Lunds universitet Fastställda av rektor 2013-06-13 i närvaro av förvaltningschef Susanne Kristensson. Föredragande var verksamhetscontroller Kristina Arnrup Thorsbro. Med stöd av 6 kap. 27, 32 och 35 §§ högsk

https://www.konstnarliga.lu.se/sites/konstnarliga.lu.se/files/foreskrifter_for_utbildning_pa_forskarniva_vid_lu.pdf - 2025-08-02

Kursbudgetmall sv

Kursbudget Välj kurs HT21 ERROR:#N/A tc={12BF3CFE-92F6-4F3E-A11B-915CDFB72DA4}: [Trådad kommentar] I din version av Excel kan du läsa den här trådade kommentaren, men eventuella ändringar i den tas bort om filen öppnas i en senare version av Excel. Läs mer: https://go.microsoft.com/fwlink/?linkid=870924 Kommentar: Översiktlig koll påå om tilldelning och antal studenter är med. Kursansvarig: Datum:

https://www.biologyeducation.lu.se/sites/biologyeducation.lu.se/files/2021-12/kursbudgetmall_sv.xlsx - 2025-08-02

Changes in plant community diversity and management effects in semi-natural meadows in southern Sweden

Popular Abstract in Swedish Bruket av slåtterängar som fodermarker har mycket gamla anor i Sverige. Slåtterängar karaktäriseras av att huvuddelen av de arter som växer här har inhemskt ursprung. De uppkom när människorna blev bofasta och klimatet så kallt att kreaturen behövde stallas under vintern (tidig Järnålder) och man därmed behövde vinterfoder till djuren. Idag är ängen en hotad biotop efteThe objectives of this thesis were to: 1) survey the vegetation in semi-natural meadows in south-central Sweden, 2) discern meadow vegetation changes in eight semi-permanent plots between studies performed in the 1960s and in 1990, 3) experimentally investigate the effects of variations in management intensity in one dry and one mesic meadow, 4) experimentally investigate the effects of different

Utveckling av Byggnadsintegrerade Solenergisystem för Energieffektiva Hus

En solfångarhybrid har utvecklats och utvärderats på avdelningen för Energi och ByggnadsDesign på Lunds Tekniska Högskola, LTH. Solfångarhybriden, ”Solfönstret”, består av solcellslaminerade absorbatorer placerade i ett fönster bakom glasrutorna. Solfönstret finns byggt i ett enfamiljshus, Solgården, i Älvkarleö utanför Gävle. För att minska investeringskostnaderna för solel har reflektorer placerA PV/T collector has been developed and evaluated at the department of Energy and Building Design at the Technical University of Lund, LTH in Sweden. The PV/T, a “solar window” made of PV cells laminated on solar absorbers is placed in a window behind the glazing. The solar window is built into a single family house, Solgården, in Älvkarleö outside Gävle in the eastern part of Sweden. To reduce th

Epidemiology and clinical manifestations of Lyme borreliosis.

Popular Abstract in Swedish Det har nu gått 20 år sedan ett utbrott av ledinflammation (arthrit), i Connecticut, USA, satte forskarna på spåret till den sjukdomsbild som vi idag kallar fästingöverförd borreliainfektion och det är snart 15 år sedan man lyckades isolera bakterien som orsakar sjukdomen, Borrelia burgdorferi. Symptomen på sjukdomen har visserligen varit kända sedan sekelskiftet men heEpidemiological and clinical characteristics of Lyme borreliosis (LB) in Sweden are described through a one year surveillance-study. The findings differed only marginally when compared to studies from the United States indicating similar clinical presentation of the disease. Incidence was 69/100.000/year with large variation between counties (26-160/100.000/year) and concentration of the disease t