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Popular Abstract in Swedish Huden och slemhinnor (mukosa) fungerar som kroppens skyddsbarriärer mot yttre angrepp av mikrober, makromolekyler och toxiner och förhindrar dessa att nå inre organ. Trots ett massivt immunskydd sker de flesta infektioner på slemhinnornas ytor. I blodcirkulationen förekommer fem olika typer av vita blodkroppar, alla med olika roller i immunförsvaret. I varje blod finns Mucosal infections trigger an inflammatory response that includes the secretion of cytokines and the recruitment of neutrophils to the infected site. This thesis describes studies examining the molecular mechanisms of neutrophil migration to sites of mucosal bacterial infection. Escherichia coli (E. coli) infection of epithelial cell layers stimulates chemokine secretion and chemokine receptor ex

"Zalmoxis" is a dramatic poem in which each character autonomously structures his own discursive lyric, expressing thus a variety of concepts over the spiritual foundation of the Dacians. The charm of each nuance in part relates in the last instance, the mode in which the author understands the proper structure of the actual dramatic perspective above the revolt of our non-Latin foundation. The ne

Popular Abstract in Swedish Streptococcus pyogenes (GAS) är en viktig sjukdomsframkallande bakterie som orsakar alltifrån lindriga infektioner som halsfluss (tonsillit) och svinkoppar (impetigo) till livshotande djupa infektioner som nekrotiserande fasceit eller ”Toxic shock syndrom”. På grund av det snabba sjukdomsförloppet i de livshotande infektionerna har streptokockerna fått beteckningen ”mörA distinguishing feature of Streptococcus pyogenes (GAS) is their ability to resist phagocytosis in whole human blood in the absence of type-specific antibodies, a property that is dependent on the expression of the surface associated M proteins. A common characteristic of M proteins is their interaction with a variety of host proteins including the complement regulatory protein factor H (FH) and

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Combustion modeling based on a multi-step global reaction mechanism [1] is applied to CFD (Computational Fluid Dynamics) analysis of a scaled swirl-stabilized 4th generation premixed DLE (Dry Low Emission) burner for gas turbines. The flexi-fuel burner consists of a MAIN premixed flame, a premixed PILOT flame and a confined RPL (Rich Pilot Lean) flame. Both steady-state RANS (Reynolds Averaged Nav

Two series of C3-benzamido and O2-anion-substituted galactopyranosides were synthesized and studied as binders to arginine-rich proteins galectin-1, -3, -7, -8N (N-terminal domain), and -9N (N-terminal domain). The first series had a 4-methylbenzamide at C3 and the anionic O2-substituent was varied. The second series varied the 4-substituent of the C3-benzamide, whereas the anionic O2 substituent

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Converging evidence suggests that heterogeneity in posttraumatic stress disorder (PTSD) arises from the presence of discrete subtypes of patients, one of which is characterized by elevated dissociative symptoms. A similar dissociative subtype has been observed among individuals displaying high hypnotic suggestibility. Here we highlight important parallels between these subtypes, drawing from resea

B-cell lymphoma (BCL) heterogeneity represents a key issue, often making the classification and clinical management of these patients challenging. In this pilot study, we outlined the first resolved view of BCL disease heterogeneity on the protein level by deciphering disease-associated plasma biomarkers, specific for chronic lymphocytic leukemia, diffuse large B-cell lymphoma, follicular lymphoma

We use the economic policy uncertainty indices of Baker, Bloom, and Davis (2016) in combination with the mixed data sampling (MIDAS) approach to investigate the US and UK stock market movements. The long-run US-UK stock market correlation depends positively on US economic policy uncertainty shocks. The US long-run stock market volatility depends significantly on the US economic policy uncertainty

Ystads kommun arbetar med en fördjupning av översiktsplanen för staden Ystad med omnejd. Ystads havsnära läge gör att klimatförändringen kommer att innebära stora utmaningar. Stigande havsnivåer väntas leda till ökade erosions- och översvämningsrisker i kustnära områden. Samtidigt är efterfrågan på havsnära boende stor och kommunen planerar att bygga ut staden mot havet. Författarna har utrett kli