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BackgroundIn a previous phase II trial, intraperitoneal local anaesthetics shortened the time interval between surgery and adjuvant chemotherapy, an endpoint associated with improved survival in advanced ovarian cancer. Our objective was to test this in a phase III trial.MethodsA double-blind, phase III parallel superiority trial was conducted at two university hospitals in Sweden, within a public

Venous thromboembolism (VTE) involves blood clot formation in veins, resulting in serious health issues. Fibrinogen, a crucial clotting protein, consists of three polypeptides encoded by the fibrinogen genes: alpha (FGA), beta (FGB) and gamma (FGG). We genotyped most common missense variants in the fibrinogen genes in relation to VTE, recurrence and family history in Malmö Thrombophilia Study, inc

Spelutvecklingsbranschen är på stark tillväxt i Sverige och under 2017 ökade antalet anställda i branschen med ca 25 procent, vilket motsvarar ca 1 000 personer. Branschen har stora utmaningar med sin kompetensförsörjning, som en konsekvens av den snabba tillväxten. I Nordamerika där branschen etablerades tidigare än i Sverige har en del studier gjorts på spelutvecklares arbetsvillkor. Flera av de

BACKGROUND: Noroviruses are the major cause of viral gastroenteritis. Disease transmission is difficult to prevent and outbreaks in healthcare facilities commonly occur. Contact with infected persons and contaminated environments are believed to be the main routes of transmission. However, noroviruses have recently been found in aerosols and airborne transmission has been suggested. The aim of our

Three different circulation mechanisms are analyzed: 1) through-flow of a river; 2) wind generated oscillations; and 3) convective currents induced by heat flow from the bottom sediments. The through-flow takes place between the ice and a depth, which is mainly determined by the conditions at the inlet of the river into the lake. Just below this depth there is a sharp thermocline. The water mass b

A detailed understanding of the dynamics of photoinduced processes occurring in the electronic excited state is essential in informing the rational design of photoactive transition-metal complexes. Here, the rate of intersystem crossing in a Cr(III)-centered spin-flip emitter is directly determined through the use of ultrafast broadband fluorescence upconversion spectroscopy (FLUPS). In this contr

Background: Multidisciplinary team meetings (MDTMs) provide an integrated team approach to ensure individualized and evidence-based treatment recommendations and best expert advice in cancer care. A growing number of patients and more complex treatment options challenge MDTM resources and evoke needs for case prioritization. In this process, decision aids could provide streamlining and standardize

Background: The incidence of atherosclerotic cardiovascular disease increases with levels of low-density lipoprotein cholesterol (LDL-C). Yet, a paradox may exist where lower LDL-C levels at myocardial infarction (MI) are associated with poorer prognoses. Objective: To assess the association between LDL-C levels at MI with risk factor burden and cause-specific outcomes. Methods: Statin-naive patie

Objectives: Various outcomes of cholinesterase inhibitor (ChEI) therapy have been observed in Alzheimer’s disease (AD). It is not clear whether the duration of treatment, type of ChEI, or dose affect mortality. We aimed to investigate the association between ChEI therapy and patient survival. Methods: The Swedish Alzheimer Treatment Study (SATS) is a prospective, observational, multicentre study t

Bluetooth is currently emerging as one of the most promising personal wireless network technologies. It is primarily designed as a cable replacement between for example a cell phone and a PDA. However the price/performance level also makes it a promising technology outside the office. The automation industry is currently showing interest in using Bluetooth for more industrial applications. However

On the Contemporary Crime Film Serial in Scandinavia and its connection to place marketing among other things.