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Global health policy in the 21st century : Challenges and opportunities to arrest the global disability burden from musculoskeletal health conditions

The profound burden of disease associated with musculoskeletal health conditions is well established. Despite the unequivocal disability burden and personal and societal consequences, relative to other non-communicable diseases (NCDs), system-level responses for musculoskeletal conditions that are commensurate with their burden have been lacking nationally and globally. Health policy priorities an

Determining Rg of IDPs from SAXS Data

There is a great interest within the research community to understand the structure-function relationship for intrinsically disordered proteins (IDPs); however, the heterogeneous distribution of conformations that IDPs can adopt limits the applicability of conventional structural biology methods. Here, scattering techniques, such as small-angle X-ray scattering, can contribute. In this chapter, we

State Segmentation and Democratic Survival in Latin America

Popular models portray that high inequality induces elites to sponsor coups and reverse democratization as a means for repressing redistributive demands. Challenging this prediction, Latin America shifted from a historical pattern of systematic democratic breakdowns to one characterized by the resilience of democracy despite extreme levels of inequality. This article argues that the reminiscence o

Adoption and Diffusion of Disruptive Technologies : The Case of Additive Manufacturing in Medical Technology Industry in Australia

This paper provides the preliminary findings of a newly granted two-year project investigating the adoption of disruptive technologies, by focusing on the case of additive manufacturing (AM) in the medical technology (MedTech) industry, particularly implant applications. This is done by (I) stakeholder mapping of the industry in Australia. This included members of industry, researchers, academics,

Measuring and Analyzing Binding Kinetics of Coupled Folding and Binding Reactions Under Pseudo-First-Order Conditions

Many intrinsically disordered proteins (IDPs) adopt a well-defined structure upon binding to their interaction partners. Kinetic characterization is a requirement for the investigation of the dynamics and mechanisms of these folding-upon-binding reactions. Here a protocol is described for the investigation of binding kinetics of bimolecular binding and folding reactions of IDPs to their ligand par

Maximum extent of the Eurasian ice sheets in the Barents and Kara Sea region during the Weichselian

Based on field investigations in northern Russia and interpretation of offshore seismic data, we have made a preliminary reconstruction of the maximum ice-sheet extent in the Barents and Kara Sea region during the Early/Middle Weichselian and the Late Weichselian. Our investigations indicate that the Barents and Kara ice sheets attained their maximum Weichselian positions in northern Russia prior

Target Tracking using Signal Strength Differences for Long-Range IoT Networks

Radio based positioning or tracking solutions typically require wideband signals or phase coherent antennas. In this paper, we present a target tracking method based on received non-coherent signal strength differences (RSSDs) between antennas for outdoor Internet-of-things (IoT) scenarios. We introduce an RSSD model based on classical path-loss models. With known antenna patterns and antenna arra

Weichselian geology and palaeo-environmental history of the central Taymyr Peninsula, Siberia, indicating no glaciation during the last global glacial maximum

The Taymyr Peninsula constitutes the eastern delimitation of a possible Kara Sea basin ice sheet. The existence of such an ice sheet during the last global glacial maximum (LGM), i.e. during the Late Weichselian/Upper Zyryansk, is favoured by some Russian scientists. However, a growing number of studies point towards a more minimalistic view concerning the areal extent of Late Weichselian/Upper Zy

Antarctic glacial history since the Last Glacial Maximum: an overview of the record on land

This overview examines available circum-Antarctic glacial history archives on land, related to developments after the Last Glacial Maximum (LGM). It considers the glacial-stratigraphic and morphologic records and also biostratigraphical information from moss banks, lake sediments and penguin rookeries, with some reference to relevant glacial marine records. It is concluded that Holocene environmen

Holocene glacial history and sea level changes on James Ross Island, Antarctic Peninsula

A reconstruction of deglaciation and associated sea-level changes on northern James Ross Island, Antarctic Peninsula, based on lithostratigraphical and geomorphological studies, shows that the initial deglaciation of presently ice-free areas occurred slightly before 7400 14C yr BP. Sea-level in connection with the deglaciation was around 30 m a.s.l. A glacier readvance in Brandy Bay, of at least 7

Subrecent moraine ridge formation on Cuff Cape, Victoria Land, Antarctica

A small bedrock ridge called Cuff Cape, protruding from an ice field in the inner part of Granite Harbour, Victoria Land, Antarctica, carries a system of moraine ridges. Cuff Cape was during deglaciation bounded to the south by a terrestrial, slow-retreat ice margin and towards the north and west by a faster-retreat, marine-based ice margin. Based on studies of contemporary processes along the pre

Late Weichselian to early Holocene sedimentation in a steep fjord/valley setting, Visdalen, Edgeøya, eastern Svalbard: glacial deposits, alluvial/colluvial-fan deltas and spit-platforms

The Visdalen valley, situated at the northwestern corner of Edgeoya, was investigated with respect to lithostratigraphy and depositional environments of the Quaternary sediments. Eight major lithostratigraphic units are recognised of which seven were deposited during the Late Weichselian to early Holocene glaciation, deglaciation and the subsequent emergence of the area, and one unit deposited pri

The Quaternary record of eastern Svalbard - an overview

The eastern part of the Svalbard archipelago and the adjacent areas of the Barents Sea were subject to extensive erosion during the Late Weichselian glaciation. Small remnants of older sediment successions have been preserved on Edgeoya, whereas a more complete succession on Kongsoya contains sediments from two different ice-free periods, both probably older than the Early Weichselian. Ice movemeh

Gravel and sand flotation: a sediment dispersal process important in certain nearshore environments

Small rafts of floating sediment, predominantly of granule and small pebble size, were observed along a tidewater coast on James Ross Island, Antarctica. The sediment was lifted from the beach by the advancing tidewater and kept afloat by surface tension. The current transported the rafts at least 100-150 m off the beach, where the rafts broke up due to wind agitation of the sea surface and the gr

Bimodal convergence : How languages interact in multicompetent language users’ speech and gestures

A central issue in studies of second and foreign language acquisition and of bilingualism is to understand what happens when two or more languages come into contact within a person, a domain often referred to as crosslinguistic influence. This chapter begins with an introduction to the notion of convergence and outlines some key theoretical issues and empirical findings. It introduces bimodal conv

Late Quaternary glacial history of the west coast of Jameson Land, East Greenland

The Late Quaternary (c. 130000-10000 BP) glacial history of the central west coast of Jameson Land, East Greenland. is reconstructed through glacial stratigraphical studies. Seven major sedimentary units are described and defined. They represent two interglacial events (where one is the Holocene). one interstadial event and two glacial events. The older interglacial event comprises marine and fluv

Glacial history of interior Jameson Land, East Greenland

The plateaus between 400 and 800 m a.s.l. around the water-divides on central and eastern Janieson Land are covered by the ‘Jameson Land Drift’ up to 50 m thick glacial. placiotluvial and glaciolacustrine deposits. A high content of far-travelled wcsterii rocks indicates the overriding by extensive glaciers channelled from the west through the Scoresby Sund basin. The Jameson Land Drift deposits h

Late Weichselian environmental history in southeastern Sweden during the deglaciation of the Scandinavian ice sheet

Late Weichselian litho-, bio-, and chronostratigraphy (14C and varves) in southeastern Sweden provide a detailed picture of the deglaciation pattern and dynamics, shore displacement, late-glacial sedimentation, and history of the landscape, vegetation, and climate. Two plausible glacial models were tested against lithologic, chronologic, and climatic data. Permafrost at and outside the ice margin