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Subclinical hypothyroidism presenting with gait abnormality.

Subclinical thyroid disease is a common disorder, particularly in middle-aged and elderly individuals. Some patients with manifest hypothyroidism complain of unsteadiness of gait. The management of subclinical hypothyroidism is controversial. A 61-year-old man presented with a mild gait abnormality. He walked unsteadily on a broad base. Examination revealed a slight cerebellar ataxic gait. Laborat

Reproductive Factors and Breast Cancer - Parity, Breastfeeding and Genetic Predisposition in Relation to Risk and Prognosis

Popular Abstract in Swedish Bröstcancer är den vanligaste cancerformen hos kvinnor världen över och den står för omkring 30% av all cancer hos kvinnor i Sverige. Varje år får ca 7000 kvinnor i Sverige diagnosen och man räknar att ca en av tio kvinnor insjuknar under sin livstid. Trots att så många får bröstcancer så är det betydligt färre kvinnor som dör av bröstcancer; för närvarande ca 1500 per The aim of this thesis was to study reproductive factors and genetic polymorphisms in relation to breast cancer risk and survival. An important component of this was to investigate the risk of specific breast cancer subgroups. The association between parity and breast cancer-specific survival was studied among 4,453 women diagnosed with breast cancer in Malmö, Sweden. It was found that: • Nullipar

Paper-thin walls: Law and the domestic in Marie Belloc Lowndes’ popular gothic

Marie Belloc Lowndes was a prolific author, publishing over forty novels in addition to plays, memoirs and a large number of short stories spanning the first five decades of the twentieth century. Most of these are now largely forgotten. Despite her obvious popularity, evidenced by a significant number of film adaptations of her novels, Lowndes has not yet reached the radar of literary studies. Th

Effects of the sigma-1 receptor agonist 1-(3,4-dimethoxyphenethyl)-4-(3-phenylpropyl)-piperazine dihydro-chloride on inflammation after stroke.

Activation of the sigma-1 receptor (Sig-1R) improves functional recovery in models of experimental stroke and is known to modulate microglia function. The present study was conducted to investigate if Sig-1R activation after experimental stroke affects mediators of the inflammatory response in the ischemic hemisphere. Male Wistar rats were subjected to transient occlusion of the middle cerebral ar