Search results

Filter

Filetype

Your search for "*" yielded 546814 hits

A validation study of a consumer wearable sleep tracker compared to a portable EEG system in naturalistic conditions

Objective: To compare a wearable device, the Fitbit Versa (FV), to a validated portable single-channel EEG system across multiple nights in a naturalistic environment. Methods: Twenty participants (10 men and 10 women) aged 25–67 years were recruited for the present study. Study duration was 14 days during which participants were asked to wear the FV daily and nightly. The study intended to reprod

Evaluating the effects of integrating trees into temperate arable systems on pest control and pollination

Agroforestry systems, which incorporate trees into agricultural land, could contribute to sustainable agricultural intensification as they have been shown to increase land productivity, biodiversity and some regulating ecosystem services. However, the effect of temperate agroforestry systems on pest control and pollination services has not been comprehensively reviewed, despite the importance of t

Internationellt jämförande pedagogik - en introduktion

Skola och utbildning utformas på olika sätt i olika länder. Samtidigt har globaliseringen blivit en viktig del i hur vi tänker och genomför utbildning. Sverige och andra länder påverkas i allt större utsträckning av globala rankningar av utbildningssystem, såsom PISA-undersökningen. I många utvecklingsländer är utbildning dessutom förknippad med biståndspolitikens villkor. Hur kan vi förstå skilln

Dual roles of TRF1 in tethering telomeres to the nuclear envelope and protecting them from fusion during meiosis

Telomeres integrity is indispensable for chromosomal stability by preventing chromosome erosion and end-to-end fusions. During meiosis, telomeres attach to the inner nuclear envelope and cluster into a highly crowded microenvironment at the bouquet stage, which requires specific mechanisms to protect the telomeres from fusion. Here, we demonstrate that germ cell-specific knockout of a shelterin co

Loss of cyclin-dependent kinase 1 impairs bone formation, but does not affect the bone-anabolic effects of parathyroid hormone

Bone mass is maintained by a balance between osteoblast-mediated bone formation and osteoclast-mediated bone resorption. Although recent genetic studies have uncovered various mechanisms that regulate osteoblast differentiation, the molecular basis of osteoblast proliferation remains unclear. Here, using an osteoblast-specific loss-of-function mouse model, we demonstrate that cyclin-dependent kina

The three cytokines IL-1β, IL-18, and IL-1α share related but distinct secretory routes

Interleukin (IL)-1 family cytokines potently regulate inflammation, with the majority of the IL-1 family proteins being secreted from immune cells via unconventional pathways. In many cases, secretion of IL-1 cytokines appears to be closely coupled to cell death, yet the secretory mechanisms involved remain poorly understood. Here, we studied the secretion of the three best-characterized members o

Priors and Posteriors in Bayesian Timing of Divergence Analyses : The Age of Butterflies Revisited

The need for robust estimates of times of divergence is essential for downstream analyses, yet assessing this robustness is still rare. We generated a time-calibrated genus-level phylogeny of butterflies (Papilionoidea), including 994 taxa, up to 10 gene fragments and an unprecedented set of 12 fossils and 10 host-plant node calibration points. We compared marginal priors and posterior distributio

Genetic and pharmacological inhibition of Cdk1 provides neuroprotection towards ischemic neuronal death

Cell cycle proteins are mainly expressed by dividing cells. However, it is well established that these molecules play additional non-canonical activities in several cell death contexts. Increasing evidence shows expression of cell cycle regulating proteins in post-mitotic cells, including mature neurons, following neuronal insult. Several cyclin-dependent kinases (Cdks) have already been shown to

Engaging with the general public on critical raw materials through the medium of electronics repair workshops.

The issue of Critical Raw Materials (CRMs) and potential interruptions to their supply andavailability due to concerns such as shortages, trade restrictions or geopolitical considerations are topicsthat are relatively unknown to the general public. Education and the dissemination of this informationamongst the general public has been promoted as a key factor in addressing this and enabling thetran