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Popular Abstract in English The secondary metabolites found in plants represent an extremely rich and limitless source of novel chemical diversity for drug discovery. In fact, some of the most important drugs currently in use today are derived from plants and they were discovered as a result of the study of medicinal plants used in traditional medicine. In this context, Bolivia is one of the most In response to the challenges of their local environments, organisms produce of a large number of chemical diverse compounds with complex stereochemistry and reactive functional groups. These characteristics enable them to interact and bind specifically to biological target molecules and exert various biological activities, and have assured that Natural products continues to be an important source

This article describes the work in progress on knowledge-based reconfiguration of a class of automation systems. The knowledge about manufacturing is represented in a number of formalisms and gathered around an ontology expressed in OWL, that allows¨generic reasoning in Description Logic. In the same time multiple representations facilitate efficient processing by a number of special-purpose reaso

Popular Abstract in Swedish Prostatacancer är Sveriges vanligaste cancersjukdom bland män. Många av de som diagnosticeras med prostatacancer får inga besvär men cirka 2400 män dör årligen av sjukdomen. Det finns flera behandlingsmetoder mot prostatacancer, men för kastrationsresistent prostatacancer, en avancerad form av prostatacancer, finns idag ingen botande behandling. Det utvecklas dock allt Prostate cancer is one of the major causes of cancer related deaths in men in Europe and the United States. In this doctoral thesis, radioimmunoimaging and -therapy of prostate cancer was investigated pre-clinically by targeting the human kallikrein-related peptidase 2 (hK2) with radiolabelled monoclonal antibodies. hK2 is an antigen that is over-expressed in prostatic neoplasms and is closely rel

Exporterande företag sätter ofta olika priser på olika marknader. Traditionellt tänker man sig att det beror på att företag anpassar kvaliteten på sina produkter efter vilken marknad de säljer på. I denna studie undersöks om prisskillnaderna istället kan förklaras av att företag aktivt sätter olika pris på olika exportmarknader för samma vara. Studien görs för alla svenska exporterande företag ino

The last years' blackouts have indicated that even when a lot of data is available, the operators at different centers do not take the proper actions in time. This depends partly on the reorganization of the centers after the deregulation and partly on the lack of reliable supportive applications when the system is close to instability. This paper uses a novel technique based on support vector mac

Discussion and presentation of the extraordinary outpour of blues music and blues musicians out of Britain in the 1960s and how this is briefly portrayed in Michelangelo Antonioni's film Blow Up (1966).

Retrospective analysis of agile projects can support identification of issues through team reflection and may enable learning and process improvements. Basing retrospectives primarily on experiences poses a risk of memory bias as people may remember events differently, which can lead to incorrect conclusions. This bias is enhanced in project retrospectives which cover a longer period compared to i

This book is an introduction to the history and theory of video art. It charts the first artistic experiments with the specificity of the video medium, the political documentary video art and video art's incorporation of narrative and pictorial codes from cinema and television. The book also presents the various theoretizations of the video medium, from Rosalind Krauss's verdict upon video as in

Radiative lifetimes of eight odd-parity states of Pt II, in the energy range from 51 408 to 64 388 cm−1, have been measured by means of the time-resolved laser-induced-fluorescence technique. Free, singly ionized platinum ions were obtained in a laser-produced plasma and a tunable laser with 1.5 ns duration pulse was used to selectively excite the Pt+ ions. The comparison of the experimental resul

This thesis contains six papers dealing with different aspects of damage and fracture in paper. The work addresses the problem of material length scales in the context of deformation and fracture of paper materials. In Paper 1, localised failure in low-basis weight paper is studied and a fracture model based on continuum damage mechanics is presented. A gradient enhanced theory is used that incorp

Introduction. Along with the great expansion of research being published in Open Access (OA) journals over the last decade, the interest for analysing the OA literature using informetric methods has also increased. Most studies have focused on the citation impact of OA journals and whether OA publishing increases the chances of a research publication being cited. Fewer analyses, however, have inve

This paper describes the credentialling system for pofessional psychologists in the Nordic Countries as it has evolved after the Second World War and current developments.