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Polymeric multilayer capsules formed by the layer-by-layer (LbL) technique are interesting candidates for the purposes of storage, encapsulation, and release of drugs and biomolecules for pharmaceutical and biomedical applications. In the current study, cellulose-based core-shell particles were developed via the LbL technique alternating two cellulose derivatives, anionic carboxymethyl-cellulose (
We present genetIC, a new code for generating initial conditions for cosmological N-body simulations. The code allows precise, user-specified alterations to be made to arbitrary regions of the simulation (while maintaining consistency with the statistical ensemble). These "genetic modifications"allow, for example, the history, mass, or environment of a target halo to be altered in order to study t
Objective: It is not clear how follow-up of coeliac disease should be optimally organised. In Malmö, Sweden, patients are followed up by general practitioners (GP), but in Linköping by gastroenterologists (GE). The aim of this study was to investigate if there were any differences in well-being and dietary adherence depending on type of follow-up. Methods: All adult patients with newly diagnosed b
Proponents of the general factor of personality have suggested that it is related to more instances of agreeable, conscientious, emotionally stable, extraverted, and open behavior. We tested this frequency hypothesis by relating the GFP from personality self-ratings to the number of instances of typical Big Five behaviors in real life. For a period of 18 consecutive days, 108 students provided res
Experience sampling often makes use of items that are similar to personality questionnaire items. Arguably, this opens up for item-popularity effects, where some respondents react to the items' level of evaluative phrasing, causing a separate factor. Gauging the risk of item popularity effects in experience sampling is important since the multifactorial aspect of the responses to the items may cau
Objective: The aim of the study was to assess the development of widespread non-joint pain (WNP) in a cohort of patients with early rheumatoid arthritis (RA), the associated health-related quality of life (HRQoL), and clinical and demographic risk factors for WNP. Method: Incident cases with RA, from the Swedish population-based study Epidemiological Investigation of Rheumatoid Arthritis (EIRA), w
In this paper, a low-complexity resistorless high-precision sub-1 V MOSFET-only voltage reference is presented. To obtain an accurate output, a curvature-compensation technique is used, canceling its logarithmic temperature dependence regardless of the value of the mobility temperature exponent (γ). The circuit is realized in 65 nm CMOS technology and yields an output voltage of 574 mV, a temperat
Proteoglycans have important biological activities. To improve the overall synthetic efficiency, a new chemoenzymatic route has been established for the proteoglycan linkage region bearing a galactose-xylose disaccharide. The xylosylated glycopeptides were synthesized via solid phase synthesis, which was followed by the addition of the galactose unit by the galactosyl transferase β4GalT7. This wor
In recent years, nonhuman ancient DNA studies have begun to focus on larger sample sizes and whole genomes, offering the potential to reveal exciting and hitherto unknown answers to ongoing biological and archaeological questions. However, one major limitation to such studies is the substantial financial and time investments still required during sample screening, due to uncertainty regarding succ
Objectives: This study determined: 1) the interobserver agreement; 2) valvular flow variation; and 3) which variables independently predicted the variation of valvular flow quantification from 4-dimensional (4D) flow cardiac magnetic resonance (CMR) with automated retrospective valve tracking at multiple sites. Background: Automated retrospective valve tracking in 4D flow CMR allows consistent ass
PURPOSE Antiangiogenic therapy using bevacizumab has proven effective for a number of cancers; however, in breast cancer (BC), there is an unmet need to identify patients who benefit from such treatment. PATIENTS AND METHODS In the NeoAva phase II clinical trial, patients (N = 132) with large (= 25 mm) human epidermal growth factor receptor 2 (HER2)-negative primary tumors were randomly assigned 1
In this chapter, we argue that to understand the interdisciplinary and transdisciplinary dialectics in sustainability science, it is useful to see sustainability science as a kind of management science, and then to highlight the hard–soft distinction in systems thinking. First, we argue that the commonly made natural–social science dichotomy is relatively unimportant and unhelpful. We then outline
Resilience is a concept that is both foundational and, at the same time, relentlessly controversial in sustainability science. It is supposed to both provide a fundamental insight into how complex adaptive systems behave—an insight with substantial normative consequences—and serve as an interdisciplinary bridge linking the disparate worlds of the natural and the social sciences. Yet the concept of
Sustainability science is fundamentally an interdisciplinary venture, but what does this interdisciplinarity imply in practice? And how can, and should, we think about interdisciplinarity more generally? These are important philosophical and methodological questions for sustainability science, the answers to which remain at least partially out of sight for a variety of reasons. This chapter has th
In the seventeenth Century, Swedish aristocratic women successfully acted as managers of landed estates, mills and iron works, and exerted agency in politics. Making qualified decisions and overseeing complex enterprises, their actions in many ways contradicted the prevailing patriarchal ideology. While explanations for this agency have stressed several intersecting factors, the role of learning a
