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Deletion of the transforming growth factor beta1 (TGF-beta1) gene in mice has previously suggested that it regulates both hematopoiesis and angiogenesis. To define the function of TGF-beta more precisely, we inactivated the TGF-beta type I receptor (T beta RI) gene by gene targeting. Mice lacking T beta RI die at midgestation, exhibiting severe defects in vascular development of the yolk sac and p

Current e-learning systems are increasing their importance in higher education. However, the state of the art of e-learning applications, besides the state of the practice, does not achieve the level of interactivity that current learning theories advocate. In this paper, the possibility of enhancing e-learning systems to achieve deep learning has been studied by replicating an experiment in which

The objective was to study ambulatory blood pressure and heart rate variability between day and night in patients with type 1 (insulin-dependent) diabetes mellitus with different degrees of diabetic nephropathy, and to evaluate the influence of autonomic neuropathy and type of antihypertensive treatment. Twenty type 1 diabetic patients with diabetic nephropathy and antihypertensive treatment were

We have investigated the formation of vesicles in the binary system of a triblock copolymer of poly(ethylene oxide) (PEO) and poly(propylene oxide) (PPO) with the average composition EO5PO68EO5 in water. Vesicles are formed when a solution of unimers is heated into a two-phase region where, at equilibrium, a concentrated lamellar phase coexists with a dilute solution of unimers. The vesicles were

Popular Abstract in Swedish Denna avhandling handlar om hur bränsleetanol kan produceras från barrved för att användas som ersättning för bensin. Den största fördelen med detta är att genom att använda etanol tillverkad av råmaterial från växtriket ökar vi inte växthuseffekten. Den koldioxid som frigörs vid förbränningen av etanolen tas åter upp av växtligheten och vi får ett slutet kretslopp. AndFuel ethanol can be produced from lignocellulosics by the enzymatic hydrolysis process, which consists of a pretreatment step prior to hydrolysis, followed by fermentation and finally refining. This thesis deals with the development of the enzymatic process using softwood as raw material. The focus has not only been on how to obtain high yields, but also on how to solve problems, which can arise i

In order to support the development of optimal housing options for older people, we need to increase our understanding of relations between aspects of housing and aspects of health in old and very old age. The objective of this cross-sectional study was to explore whether and how aspects of housing are related to life satisfaction and perceived health among very old, single-living Swedish people.

A group of 74 psychiatric patients who had undergone psychodynamic therapy (PDT; 24 women, 10 men), cognitive psychotherapy (CPT; 9 women, 2 men) or cognitive behavioral therapy (CBT; 17 women, 12 men) were given the Defense Mechanism Technique modified (DMTm), a percept-genetic technique, both prior to therapy and four months after completing it, at which time they evaluated by questionnaire the

The yeast Saccharomyces cerevisiae is characterized by its ability to: (a) degrade glucose or fructose to ethanol, even in the presence of oxygen (Crabtree effect); (b) grow in the absence of oxygen; and (c) generate respiratory-deficient mitochondrial mutants, so-called petites. How unique are these properties among yeasts in the Saccharomyces clade, and what is their origin? Recent progress in g

Objectives: The aim of this survey was to compare stressful life events, social support and sense of coherence (SOC) between frequent attenders (FAs) and normal attenders (controls) in primary health care. Study design: A cross-sectional study was conducted in a primary healthcare centre in the south-west of Sweden. Methods: A postal questionnaire was sent to 263 frequent attenders and 703 normal

A search for a narrow baryonic resonance decaying to K(s)(0)p or K-s(0)(p) over bar is carried out in deep inelastic ep scattering with the H1 detector at HERA. ss Such a resonance could be a strange pentaquark Theta(+), evidence for which has been reported by several experiments. The K(s)(0)p and K-s(0)(p) over bar invariant ss mass distributions presented here do not show any significant peak in

Popular Abstract in Swedish Bakgrund: Det första elektrokardiogrammet (EKG) utfördes 1887 av Augustus Desiré Waller. Det innebar att spänningsskillnader mellan olika delar av hjärtat, under hjärtats arbete dvs. vid upprepade sammandragningar och avslappningar, kunde registreras med elektroder på kroppens yta. Metoden utvecklades vidare av Willem Einthoven, som fick nobelpriset för sitt arbete 1924Background and Methods: Signal-averaging ECG (SAECG), a bioelectrical processing method, is a further development of the conventional ECG. SAECG can detect voltage potentials in the microvolt range and provide a noise-reduced determination of QRS duration. Extended frequency spectra can be analysed. In adult patients after myocardial infarction it is used to predict the risk for arrhythmias and su

Vanadia was deposited on TiO2, ZrO2, HfO2, Nb2O5, and Ta2O5 supports using impregnation with either an oxalic acid solution of NH4VO3 or a solution of vanadyl acetylacetonate in ethanol. Prepared samples, with a nominal vanadia content in the range 0.5–2 monolayers, were characterized with X-ray diffraction (XRD), X-ray photoelectron spectroscopy (XPS), Raman and infrared spectroscopy, and were us

We describe the qualitative dynamics and bifurcation set for a laser with injected signal for small cavity detunings. The main organizing center is the Hopf-saddle-node bifurcation from where a secondary Hopf bifurcation of a periodic orbit originates. We show that the laser's stable cw solution existing for low injections, also suffers a secondary Hopf bifurcation. The resonance structure of both