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Generation and evolution of human antibody repertoires

This thesis, which is based on five original papers, covers different aspects of antibody specificity and diversity, with the overall goal to understand the makeup of antibody repertoires and their functionality as they occur in vivo or as they are developed in the laboratory. Besides their importance in the adaptive immune response, antibodies have emerged as an invaluable tool in applications r

The Threat or Promise of Popular Therapy? A Feminist Reading of Narratives of 'the Good Couple'

Popular therapeutic culture—such as self-help books, TV programmes, and Internet resources—is growing rapidly and posing important questions for feminist research and politics. On the one hand, it can be seen as a challenge to the public sphere in terms of what can be shown and said and by whom, with the emancipatory potential of giving political credentials to the personal. On the other, it can b

Corruption in a culture of money: Understanding social norms in post-Soviet Uzbekistan

The aim of this article is to explore the social meaning and ordinary activities surrounding informal transactions in order to better understand the social context forming the premises and informing the meaning of corruption in Uzbekistan. A theoretically founded hypothesis is that informal transactions in Uzbek society reflect different cultural meanings than in the Western world. If this is true

The Threat to the Baltic Salmon - a Combination of Persistent Pollutants, Parasite and Oxidative Stress

Popular Abstract in Swedish Organiska miljögifter finns idag i hela världen och har spridits dels genom lokala utsläpp och dels genom atmosfärisk transport. Trots att flera miljögifter (som insektsmedlet DDT och industrikemikalien PCB) har varit förbjudna sedan början av 1970-talet ser vi fortfarande höga halter av miljögifter i vår natur. Dels beror detta på att organiska miljögifter är svårnedbrAtlantic salmon (Salmo salar) from the Baltic Sea suffer from a reproduction disease known as the M74-syndrome. Newly hatched fry develop nerve disorders and die between 3-5 days after the first symptoms are seen. This is a maternally transmitted disease that is casued by a thiamine (vitamin B1) deficiency. The factor(s) that casue(s) this thiamine deficiency are largely unknown. However, several