An important question in human genetics is the extent to which genes causing monogenic forms of disease harbor common variants that may contribute to the more typical form of that disease. We aimed to comprehensively evaluate the extent to which common variation irk the six known maturity-onset diabetes of the young (MODY) genes, which cause a monogenic form of type 2 diabetes, is associated with

Popular Abstract in Swedish Denna avhandling tillhör området professions- och skolutvecklingsforskning. Avhandlingen tar upp hur förskolepersonal konstruerar sig som professionella subjekt, dvs hur förskolepersonal skapar sitt professionella jag, sin identitet, utifrån individuella såväl som kollektiva erfarenheter. Avhandlingen tar också upp på vilket sätt reflekterande samtal bidrar till denna sA major aim initially was to create a forum for reflective dialogue on the preschool professions and how it is experienced on a daily basis, so as to be able to investigate how members of the preschool staff construct their professional subject. The following are major questions that were posed: How do preschool staff members talk about themselves, their profession and their work? In what way does

Eight patients with Acanthamoeba keratitis were diagnosed and treated at our clinic between February 1991 and February 1993. Five of these were contact lens wearers, two had suffered recent corneal trauma and one had recently undergone penetrating keratoplasty. The diagnoses were based on both culture and histological examination of biopsy material in three cases, on culture alone in two cases and

We establish the existence of solitary wave solutions with exponential decay at infinity for a nonlinear dispersive partial differential equation. As a by-product, the existence of smooth solitary waves for the Camassa-Holm equation, modeling water waves and waves in elastic rods, is obtained.

Postmenopausal decline of estrogen production is associated with development of several degenerative disorders such as osteoporosis, neuroinflammatory diseases and vascular wall degeneration. These are associated with the activation of the cells of the monocyte-macrophage system in a context-dependent manner. Estrogen regulates differentiation, maturation and function of many cell types in this sy

The metabolites of two different Ripartites species, R. tricholoma (A. & S. ex Fr.) Karst. and R. metrodii Huijsm. were investigated. Three new sesquiterpenes were isolated from three different strains. In addition, the strains produced 13-oxo-9(Z),11(E)-octadecadienoic acid, psathyrellon A, 5-desoxyilludosin, an illudane (previously isolated from a Bovista sp.) 96042 and demethylovalicin, fiv

Background. Early enteral nutrition with solutions containing prebiotics (fiber) and probiotics (Lactobacillus) is suggested to reduce bacterial translocation and minimize the incidence of infections after liver transplantation. Methods. In a prospective, randomized placebo-controlled trial consisting of 95 patients, we compared the incidence of postoperative infections and other complications aft

Objective: The aims of this study were to investigate outcomes of older people's use of powered wheelchairs and risk factors for negative outcomes. Design: The study was a cross-sectional interview-study including 111 powered wheelchair users over 65 years of age. Results: All participants used their powered wheelchair in the summer; nearly all users regarded it as important and found that it gave

Palaeomagnetic data are used to study the configurations of continents during the Proterozoic. Applying stringent reliability criteria, the positions of the continents at 12 times in the 2.45- to 1.00-Ga period have been constructed. The continents lie predominantly in low to intermediate latitudes. The sedimentological indicators of palaeoclimate are generally consistent with the palaeomagnetic l

A search for single top production (e(+)e(-) --> t (c) over bar) via flavour changing neutral currents (FCNC) was performed using the data taken by the DELPHI detector at LEP2. The data analyzed have been accumulated at center-of-mass energies ranging from 189 to 208 GeV. Limits at 95% confidence level were obtained on the anomalous coupling parameters kappa(gamma) and kappa(Z). (C) 2004 Published

Background: Surgical removal of the stomach (gastrectomy, Gx) induces osteopenia. In this study we compared the osteopenic effect of Gx with that induced by calcium (Ca) deficiency. Methods: Young male rats were subjected to Gx and/or low Ca diet (-Ca). A group of Gx rats received standard diet + oral Ca supplementation (+ Ca). The rats were killed at various times after the operation/start of tre

The conventional inversion of surface waves depends on modal identification of measured dispersion curves, which can be ambiguous. It is possible to avoid mode-number identification and extraction by inverting the complete phase-velocity spectrum obtained from a multichannel record. We use the fast simulated annealing (FSA) global search algorithm to minimize the difference between the measured ph

Artikeln diskuterar möjligheten för arkeologer att utifrån materiella källor diskutera ritual i det förflutna. Med utgångspunkt i ett avhandlingsarbete om mesolitiska gravar (Nilsson Stutz 2003) föreslås en kombination av handlingsteori och metoden ”anthropologie de terrain” som en väg till insikt. Författaren understryker behovet av att synkronisera arkeologisk teori och metod. Kan vi studera oc

During surfactant treatment of respiratory distress syndrome, 23 premature newborns were investigated with continuous amplitude-integrated electroencephalography (cerebral function monitors). Simultaneously, arterial blood pressure and transcutaneous blood gas values were recorded. A short (less than 10 minutes) but significant decrease in cerebral activity was seen in almost all neonates immediat

We investigate shot noise of photon-excited electron-hole pairs in open multiterminal, multichannel chaotic dots. Coulomb interactions in the dot are treated self-consistently giving a gauge-invariant expression for the finite frequency correlations. The Coulomb interactions decrease the noise; the strong interaction limit coincides with the noninteracting adiabatic limit. Inelastic scattering and