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Should we start debating medical ethics in our daily practice?
Markets for energy efficiency: Exploring the implications of an EU-wide 'Tradable White Certificate' scheme
Recent developments in European energy policy reveal an increasing interest in implementing the so-called ‘Tradable White Certificate’ (TWC) schemes to improve energy efficiency. Based on three evaluation criteria (cost-effectiveness, environmental effectiveness and distributional equity) this paper analyses the implications of implementing a European-wide TWC scheme targeting the household and co
Entrepreneurial characteristics in Switzerland and the UK: A comparative study of techno-entrepreneurs
The entrepreneur is the central actor in generating entrepreneurial activity. Thus, it is important to understand the motivational characteristics and variables associated with entrepreneurial behavior spurring people to become entrepreneurs. For this study, a comparative analysis of high-tech entrepreneurs in Switzerland and the UK was undertaken to determine the extent to which they differ in te
Increased QT dispersion and loss of sinus rhythm as risk factors for late sudden death after mustard or senning procedures for transposition of the great arteries
Increased QT dispersion and loss of sinus rhythm were both associated with sudden cardiac death in patients with transposition of the great arteries after Mustard and Senning operations at the early and late postoperative periods. A combination of increased QT dispersion with loss of sinus rhythm increases the positive predictive value for sudden cardiac death in patients with transposition of the
Parametrization of the Zeeman effect for hydrogen-like spectra in high-temperature plasmas
We present a method for parametrizing the Zeeman effect in hydrogen-like systems in high-temperature plasmas, where the fine-structure is completely unresolved. The method is based on the observation that the different polarization components behave collectively like separate entities, with simple relations. The entire Zeeman pattern can then be reduced to just three components, whose dependence o
Hyperplasia of histaime-depleted enterochromaffin-like cells in rat stomach using omeprazole and a-fluoromethylhistidine
In the rat, gastric histamine is stored mainly in the enterochromaffinlike cells. Gastrin releases histamine from these cells, and long-term hypergastrinemia results in hyperplasia. The effect of sustained hypergastrinemia on histamine-depleted enterochromaffinlike cells was studied by measuring histidine decarboxylase activity and histamine concentrations and by using quantitative histology. Hype
Studies on phenotypic expression patterns of proteases and protease inhibitors in benign compared to malignant prostate tissues
Quantification of bacterial subgroups in soil: comparison of DNA extracted directly from soil or from cells previously released by density gradient centrifugation
All molecular analyses of soil bacterial diversity are based on the extraction of a representative fraction of cellular DNA. Methods of DNA extraction for this purpose are divided into two categories: those in which cells are lysed within the soil (direct extraction) and those in which cells are first removed from soil (cell extraction) and then lysed. The purpose of this study was to compare a me
Characterization of the xylose-transporting properties of yeast hexose transporters and their influence on xylose utilization
For an economically feasible production of ethanol from plant biomass by microbial cells, the fermentation of xylose is important. As xylose uptake might be a limiting step for xylose fermentation by recombinant xylose-utilizing Saccharomyces cerevisiae cells a study of xylose uptake was performed. After deletion of all of the 18 hexose-transporter genes, the ability of the cells to take up and to
Influence of adsorption and concentration polarisation on membrane performance during ultrafiltration of a non-ionic surfactant
Surfactants are present in almost all aqueous solutions-either as additives for different purposes, or because they occur naturally. Because of the common occurrence of surfactants in process water it is important to know how they behave in membrane processes. Ultrafiltration membranes allow almost complete passage of surfactant monomers, but reject micelles almost completely. Concentration polari
Fusion gene-mediated truncation of RUNX1 as a potential mechanism underlying disease progression in the 8p11 myeloproliferative syndrome.
The 8p11 myeloproliferative syndrome (EMS) is a chronic myeloproliferative disorder molecularly characterized by fusion of various 5' partner genes to the 3' part of the fibroblast growth factor receptor 1 (FGFR1) gene at 8p, resulting in constitutive activation of the tyrosine kinase activity contained within FGFR1. EMS is associated with a high risk of transformation to acute myeloid leukemia (A
Retrograde axonal transport of JNK signaling molecules influence injury induced nuclear changes in p-c-Jun and ATF3 in adult rat sensory neurons
In the present study, we investigated if the previously observed JNK-mediated activation of c-Jun and induction of ATF3 could be ascribed to axonal transport of JNK signaling components, or if axonal transport of the transcription factors themselves contributes to the nuclear changes in injured sensory neurons. We observed retrograde axonal transport of a number of JNK upstream kinases in ligated
Effects of ionic strength and denaturation time on polyethyleneglycol self-diffusion in whey protein solutions and gels visualized by nuclear magnetic resonance
Pulsed field gradient NMR spectroscopy was used to determine the poly(ethylene glycol) (PEG) self-diffusion coefficient (D-PEG) as a function of NaCl concentration (C-NaCl) and denaturation time (t(D)) in whey protein solutions and gels. D-PEG in the gel decreased with increasing C-NaCl concentrations and increased with increasing t(D); the increase ceased for all PEGs when the gel was fixed. This
Polymorphisms in the CTLA-4 gene and inhibitor development in patients with severe hemophilia A
Capsaicin-sensitive sensory fibers in the islets of Langerhans contribute to defective insulin secretion in Zucker diabetic rat, an animal model for some aspects of human type 2 diabetes
The system that regulates insulin secretion from beta-cells in the islet of Langerhans has a capsaicin-sensitive inhibitory component. As calcitonin gene-related peptide (CGRP)-expressing primary sensory fibers innervate the islets, and a major proportion of the CGRP-containing primary sensory neurons is sensitive to capsaicin, the islet-innervating sensory fibers may represent the capsaicin-sensi
A stratigraphically significant conodont fauna from the base of the Tetragraptus approximatus Zone at Holsbrotten, Mt. Hunneberg, SW Sweden
A diverse conodont collection representing the Oelandodus elongatus-Acodus deltatus deltatus Subzone of the Paroistodus proteus Zone has been retrieved from a sample from the E bed at Holsbrotten on the west side of Mt. Hunneberg. This bed marks the base of the Tetragraptus approximatus Zone at the nearby Diabasbrottet section, the recently ratified stratotype for the base of the Second Global Sta
Fascial closure and factors associated with mortality in decompressed patients with abdominal compartment syndrome treated with the vac and mesh mediated fascial traction (VACM)
A missense mutation in ftsZ differentially affects vegetative and developmentally controlled cell division in Streptomyces coelicolor A3(2)
Streptomyces coelicolor A3(2) undergoes at least two kinds of cell division: vegetative septation leading to cross-walls in the substrate mycelium; and developmentally regulated sporulation septation in aerial hyphae. By isolation and characterization of a non-sporulating ftsZ mutant, we demonstrate a difference between the two types of septation. The ftsZ17(Spo) allele gave rise to a classical wh
The role of microorganisms in biliary tract disease.
The biliary tract is normally sterile, but bile-tolerant bacteria are frequently isolated from patients with cholecystitis. Since the identification of about 25 Helicobacter species, some of which may grow in bile, studies have addressed the role of these organisms in primary biliary cirrhosis, primary sclerosing cholangitis, and cholelithiasis. Most of these bacteria show the presence of Helicoba