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What role for network governance in urban low carbon transitions?

Many cities around the world have taken a pioneering role in tackling climate change and they will be key players in a possible transition to a future low carbon society. However, cities are at the same time constrained and act in a world of multi-level governance where local decision makers are dependent on both higher political levels and other actors in society. In this situation network govern

Some comments on the substituted judgement standard.

On a traditional interpretation of the substituted judgement standard (SJS) a person who makes treatment decisions on behalf of a non-competent patient (e.g. concerning euthanasia) ought to decide as the patient would have decided had she been competent. I propose an alternative interpretation of SJS in which the surrogate is required to infer what the patient actually thought about these end-of-l

Asymmetric Cooperation among Wireless Relays with Linear Precoding

Wireless relays extend coverage, improve spectral efficiency, and enhance reliability and rates of wireless cellular communication systems. In this work, we introduce the fundamental notion of asymmetric cooperation among cooperating relays in cellular downlinks - different relays are party to different but overlapping knowledge about the messages transmitted from the base station. We argue that a

Sources for PM air pollution in the Po Plain, Italy: II. Probabilistic uncertainty characterization and sensitivity analysis of secondary and primary sources

Very high levels of ambient particulate matter (PM) are frequently encountered in the north of Italy and air quality limits are regularly exceeded. To obtain quantitative information on the pollution sources and to gain understanding of the dynamics of pollution episodes in this populated area PM10 and/or PM2.5 samples were collected daily at nine urban to regional sites distributed over the centr

Estimating heritabilities and genetic correlations: comparing the 'animal model' with parent-offspring regression using data from a natural population.

Quantitative genetic parameters are nowadays more frequently estimated with restricted maximum likelihood using the 'animal model' than with traditional methods such as parent-offspring regressions. These methods have however rarely been evaluated using equivalent data sets. We compare heritabilities and genetic correlations from animal model and parent-offspring analyses, respectively, using data

Contemporary approaches for imaging skeletal metastasis.

The skeleton is a common site of cancer metastasis. Notably high incidences of bone lesions are found for breast, prostate, and renal carcinoma. Malignant bone tumors result in significant patient morbidity. Identification of these lesions is a critical step to accurately stratify patients, guide treatment course, monitor disease progression, and evaluate response to therapy. Diagnosis of cancer i

Combining multiway principal component analysis (MPCA) and clustering for efficient data mining of historical data sets of SBR processes

A methodology based on Principal Component Analysis (PCA) and clustering is evaluated for process monitoring and process analysis of a pilot-scale SBR removing nitrogen and phosphorus. The first step of this method is to build a multi-way PCA (MPCA) model using the historical process data. In the second step, the principal scores and the Q-statistics resulting from the MPCA model are fed to the LA

Functional Recruitment of the Human Complement Inhibitor C4BP to Yersinia pseudotuberculosis Outer Membrane Protein Ail

All is a 17-kDa chromosomally encoded outer membrane protein that mediates serum resistance (complement resistance) in the pathogenic Yersiniae (Yersinia pestis, Y. enterocolitica, and Y. pseudotuberculosis). In this article, we demonstrate that Y pseudotuberculosis Ail from strains PB1, 2812/79, and YPIII/pIB1 (serotypes O:1a, O:1b, and O:3, respectively) can bind the inhibitor of the classical a

Using service simulation to analyse the satisfaction with the processes of intensive care unit in the hospital: the perspective of the patient and the family

In the hospital, intensive care unit (ICU) is an isolated space where patients with acute symptoms are treated. When the patients are in ICU, their families are usually in psychological crisis and under great pressure. The value of ICU is thus to provide a complete ICU service by which not only the patients receive good treatment, but the feelings of family members are also considered and managed.

The Role of Inosine-5'-Monophosphate Dehydrogenase in Thiopurine Metabolism in Patients With Inflammatory Bowel Disease.

BACKGROUND:: There is a large interindividual variability in thiopurine metabolism. High concentrations of methylthioinosine-5'-monophosphate (meTIMP) and low concentrations of 6-thioguanine nucleotides (6-TGNs) have been associated with a lower response rate and an increased risk of adverse events. In this study, the role of inosine-5'-monophosphate dehydrogenase (IMPDH) for differences in metabo

Effect of multiplicity, laterality, and age at onset of breast cancer on familial risk of breast cancer: a nationwide prospective cohort study

The objective of this nationwide prospective cohort study is to find out the risk of breast cancer (BC) in relatives of patients with multiple BCs by laterality and age at diagnosis of first BC. Having family history of single (HR 1.8; 95 % CI 1.8-1.9) or multiple (HR 2.7; 95 % CI 2.6-2.9) BC was associated with higher risk of BC. Those with an FDR with contralateral BC at any age had the highest

Juridifiering som institutionell förändring. Om mötet mellan straffrätt och socialrätt vid interorganisatorisk samverkan

Denna artikel handlar om vad som sker i mötet mellan straffrätt och socialrätt vid interorganisatorisk samverkan i en kontext av barnahus - där socialtjänst, hälso- och sjukvård samt polis- och åklagarmyndigheter samverkar under ett gemensamt tak kring utredningar av misstänkta brott mot barn. Utifrån ett rättssociologiskt institutionellt perspektiv presenteras och vidareutvecklas förståelsen för

An audit analysis of a guideline for the investigation and initial therapy of diarrhea negative (atypical) hemolytic uremic syndrome

In 2009, the European Paediatric Study Group for Haemolytic Uraemic Syndrome (HUS) published a clinical practice guideline for the investigation and initial therapy of diarrhea-negative HUS (now more widely referred to as atypical HUS, aHUS). The therapeutic component of the guideline (comprising early, high-volume plasmapheresis) was derived from anecdotal evidence and expert consensus, and the a

The Artelon CMC spacer compared with tendon interposition arthroplasty

Background and purpose The Artelon CMC spacer is designed for surgical treatment of osteoarthritis (OA) in the carpometacarpal joint of the thumb (CMC-I). Good results using this degradable device were previously presented in a pilot study. We now present results from a larger randomized, controlled, multicenter study. Patients and methods 109 patients (94 females) with a mean age of 60 (42-83) ye

Effects of 17α-ethinylestradiol on individual life-history parameters and estimated population growth rates of the freshwater gastropods Radix balthica and Bithynia tentaculata.

Studies of aquatic environments exposed to 17α-ethinylestradiol (EE2) have demonstrated detrimental effects on fish communities. However, much less is known about effects on macro-invertebrates and especially how long-term exposure may affect critical life stages and ultimately population dynamics. We studied the effects of EE2 on relevant endpoints for population growth in two common freshwater g