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A single intradermal injection of the mineral oil pristane in susceptible DA.1F rats induces erosive arthritis closely mimicking rheumatoid arthritis (RA). Pristane-induced arthritis (PIA) is driven by autoreactive T cells but no autoantigen has been identified to date. We therefore analyzed B and T cell responses to autoantigens potentially involved in the pathogenesis of RA, including IgG, citru

A group of Swedish oncologists and hospital physicists have estimated the number of patients in Sweden suitable for proton beam therapy. The estimations have been based on current statistics of tumour incidence, number of patients potentially eligible for radiation treatment, scientific support from clinical trials and model dose planning studies and knowledge of the dose-response relations of dif

We present C 1s x-ray absorption, x-ray emission, and resonant inelastic x-ray scattering (RIXS) spectra of single-phase crystalline K3C60. The comparison to valence-band photoelectron spectra from the same sample facilitates identification of the contribution from surface and bulk electronic states in the latter. Bulk-sensitive techniques show that the valence bands of K3C60 and pure C60 are char

Objective: This study was performed to investigate the influence of calcitonin gene-related peptide (CGRP) and substance P (SP) on the intra-urethral pressure in female rats, as both these neuropeptides have been demonstrated to occur in nerve fibres throughout all layers of the intrinsic external urethral sphincter of the rat. Material and Methods: Both CGRP and SP were administered intra-arteria

Abstract is not available.

Cytokines have been shown to have important roles in lymphopoiesis. However, many questions remain unresolved. Among other, while the action of interleukin (IL)-7 in alpha beta T cell development in mouse seems to be largely mediated through permissive survival signaling, the possible permissive role of IL-7 in early B cell development is disputed. Furthermore, FMS-like tyrosine kinase-3 ligand (F

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This work discusses methods to obtain reference following on unstable systems. The task is critical; introduction of refernce signal might cause instability in some cases. It is thus interesting to develop strategies that offer acceptable reference following, but also guarantees stability. In practice similiar problems arises in flight control systems for unstable fighter aircrafts. Experimental v

The European food service market was estimated, in 1999, to be worth US$293 billion with high profit margins and a growth rate of 2.75%. Future demand for value-added products and high levels of customization will stress the issue of keeping profit margins in the food service industry. Packaging is a critical issue, because it adheres to the product throughout the entire food service supply chain.

Analysis of atrial rhythm is important in the treatment and management of patients with atrial fibrillation. Several algorithms exist for extracting the atrial signal from the electrocardiogram (ECG) in atrial fibrillation, but there are few reports on how well these techniques are able to recover the atrial signal. We assessed and compared three algorithms for extracting the atria] signal from th

The class I genes of the major histocompatibility complex (Mhc) are here investigated for the first time in a passerine bird. The great reed warbler is a rare species in Sweden with a few semi-isolated populations. Yet, we found extensive Mhc class I variation in the study population. The variable exon 3, corresponding to the alpha(2) domain, was amplified from genomic DNA with degenerated primers

Med utgångspunkt i ett fall, en ryttare som drunknade då han försökte ta sig över Helgeån, diskuteras hur drunkningar utreddes i början av 1700-talet

Background and Purpose - Depression after stroke is often described as underdiagnosed and undertreated. However, there are few data on self-reported depression and use of antidepressants in stroke patients at large. Materials and Methods - In the Swedish national quality assessment register, Riks-Stroke, 15 747 stroke survivors are recorded. They were asked about depressive mood and antidepressant