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The compatibility between the implementation of information and communication technologies (ICTs) strategies and the bottom-up approach in the developmental process is assessed. In order to put the theoretical arguments into practice, the existing benefits and obstacles of implementing such strategies in reality are presented. Deriving from the analysis of the bottom-up approach is the identificat

The very large multiplicity of charged particles encountered in lead on lead collisions in the WA98 experiment at the CERN SPS provided new experimental challenges. Tracking detectors read out with high granularity were developed to achieve accurate position information in two dimensions, with the aim of reconstructing tracks with a minimum of combinatorial difficulties. A tracking system based on

Secretagogin is a newly identified calcium-binding protein selectively expressed in neuroendocrine tissue and pancreatic beta-cells. The function of secretagogin is unknown, but it has been suggested in beta-cells to influence calcium-influx, insulin secretion and proliferation, and has been observed downregulated in diabetes-prone BB rat islets exposed to cytokines. In the present study, we ident

Povidon är en polymer som används som stabiliseringsmedel i många läkemedel och vissa kosmetika. Povidon har ansetts vara atoxiskt och inte allergiframkallande. Vi beskriver ett fall av överkänslighet mot povidon som nyligen rapporterats till biverkningsenheten i Lund. Vi har även gjort en litteratursökning och sammanfattar tidigare publicerade fall. Allergi mot povidon har dokumenterats med prick

LTH har, tillsammans med KTH och VTI, med Vägverket och Kommunikationsforskningsberedningen som finansiärer, i uppdrag att utveckla nya modeller för effektberäkning av vägtrafikanläggningar. Som en del i detta arbete görs en inventering av kunskapsläge och kunskapsbrister. Redovisningen av detta avseende framkomlighet i korsningar utan trafiksignaler görs i denna rapport. Ca 200 referenser har stu

The nucleotide sequences of the variable region genes encoding five different human, high affinity antibodies, specific for the major neutralization determinant (AD-1) expressed by human cytomegalovirus glycoprotein B (gp58/116), have been determined. Three of the five heavy chain variable regions belonged to the small VHV-family, although they combined with a diverse set of light chains (V kappa

Neurons were obtained from the CA1 region of the hippocampus of newborn rats and maintained in culture. Channels were activated by pentobarbitone in cell-attached, inside-out or outside-out patches, normally by applying pentobarbitone in flowing bath solution. Currents were outwardly rectifying and blocked by bicuculline, properties of GABAA channels in these cells. Maximum channel conductance inc

Thirty rats were subjected to a standardized critical aortic injury and divided into six groups. In addition to controls, the animals were treated with a pneumatic antishock garment (PASG), massive intravenous or intra-aortic saline infusion, or PASG in combination with either massive intravenous or intra-aortic saline infusion. Twenty-six rats were subjected to a standardized hepatic injury and d

Load balancing is a very important and complex problem in computational grids. A computational grid differs from traditional high-performance computing systems in the heterogeneity of the computing nodes, as well as the communication links that connect the different nodes together. There is a need to develop algorithms that can capture this complexity yet can be easily implemented and used to solv

A link between unsaturated fatty acids or phytonutrients and reduced risk of colorectal cancer has been suggested. However, the effects of higher intake of dietary sources of these nutrients, such as the nuts and seeds food group, are less clear. The objective of this study was to determine the effects of nut and seed intake on colorectal cancer risk within the European Prospective Investigation i

We reviewed results of SBRT treatment of 138 patients with medically inoperable stage I NSCLC treated during 1996 - 2003 at five different centres in Sweden and Denmark. Mean age was 74 years ( range 56 - 90) with 69 men and 72 women. SBRT was delivered using a 3D conformal multifield technique and a stereotactic body frame. Doses delivered were 30 - 48 Gy (65% isodose at the periphery of planning

When diffusion coefficients are measured with the cup method, the exposed area is often less than the area of the sample. Because of this masking effect the measured diffusion coefficient is overestimated. The present article presents simple formulas based on two-dimensional analytical solutions to correct for this in cylindrical cup samples. Different cases of anisotropical diffusion are dealt wi

The reactions of isoprenyl caffeate, the strongest allergen known to be present in propolis, with plausible functional groups of proteins were studied. The thiols glutathione and cysteine, which add to isoprenyl caffeate after having been oxidised to the corresponding quinone, served as model substances. The structure of the thiol adducts was determined by spectroscopic methods, addition being fou

Although many of the chromosomal abnormalities in hematologic malignancies are identifiable cytogenetically, some are only detectable using molecular methods. We describe a novel cryptic t(7;21)(p22;q22) in acute myeloid leukemia (AML). FISH, 3'RACE, and RT-PCR revealed a fusion involving RUNX1 and the ubiquitin-specific protease (USP) gene USP42. The genomic breakpoint was in intron 7 of RUNX1 an