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We propose reframing one of the key questions in the field of language evolution as what was the original human-specific communicative system? With the help of cognitive semiotics, first we clarify the difference between signals, which characterize animal communication, and signs, which do not replace but complement signals in human communication. We claim that the evolution of bodily mimesis allo
Purpose: Agile is the new popular management change method and agile has lots of momentum. Management consulting firms are promoting agile via articles and newsletters. While history does not repeat itself, it often rhymes, and thus agile will probably be a successful change effort in some organizations. On the other hand, there is a high probability that agile will not deliver the expected result
Maintaining social relationships depends on the ability to recognize partners or group members against other individuals. This is especially important in animals with relatively stable social groups. The amphisbaenian Trogonophis wiegmanni is a semi blind fossorial reptile that spends its entire life underground where it interacts with mates and social partners. In this environment, visual cues ar
Background: Chronic breathlessness has devastating consequences. The minimal clinically important difference (MCID) for current intensity has been estimated as 9 mm on a 100-mm visual analogue scale (VAS). We aimed to determine MCIDs for commonly used dimensions and recall periods: the current unpleasantness and current, average, best and worst intensity of the past 24 h for chronic breathlessness
Background: Disturbance in the oropharyngeal microbiota is common in hospitalized patients and contributes to the development of nosocomial pneumonia. Lactiplantibacillus plantarum 299 and 299v (Lp299 and Lp299v) are probiotic bacteria with beneficial effects on the human microbiome. Aim: To investigate how Lp299 and Lp299v affect the growth of nosocomial oropharyngeal pathogens in vitro and to ev
Aims: High expression of the RNA-binding motif protein 3 (RBM3) correlates with improved prognosis in several major types of cancer. The aim of the present study was to examine the prognostic value of RBM3 protein and mRNA expression in non-small cell lung cancer (NSCLC). Methods and results: Immunohistochemical expression of RBM3 was evaluated in surgically treated NSCLC from two independent pati
Artificial intelligence (AI) algorithms for automated classification of skin diseases are available to the con-sumer market. Studies of their diagnostic accuracy are rare. We assessed the diagnostic accuracy of an open-access AI application (Skin Image Search™) for recognition of skin diseases. Clinical images including tumours, infective and inflammatory skin diseases were collected at the Depart
Objectives: The novel MOTor Imagery to Facilitate Sensorimotor Re-Learning (MOTIFS) model takes a uniquely holistic approach by integrating mental and physical aspects into current training programs. The aim of this trial was to evaluate enjoyment of MOTIFS training as compared to Care-as-Usual (CaU) knee injury and/or rehabilitation training. The primary hypothesis was that enjoyment would be gre
In this study, microparticle coatings and nanoparticle coatings were fabricated on copper surfaces by an electrochemical deposition method and an electrophoretic deposition method, respectively. Pool boiling of NOVEC-649 was experimentally studied on the coated surfaces, concerning heat transfer, bubble dynamics, and critical heat fluxes. Compared with a smooth surface, heat transfer coefficients
Objective. Patients with ANCA-associated vasculitides (AAV) exhibit higher rates of malignancy than the general population. We assessed whether the cancer risk is increased in a well-characterized population-based cohort of AAV in southern Sweden, followed for a median time of 8 years. Methods. With case record review, the outcomes and malignancy development in a cohort of 195 patients with AAV [g
Commonly, heat transfer performance of a nanofluid is enhanced by increasing the mass fraction of nanoparticles due to an improvement of the thermo-physical properties. However, increasing the number of nanoparticles in the base fluid will result in an increase of the nanofluid viscosity. This research aims to investigate natural convective heat transfer for an electric heater filled with various
Objectives: To investigate the association between precarious employment and health in a sample of non-standard employees in Stockholm County, Sweden, by addressing three specific research questions: is the degree of precarious employment (low, moderate, high) associated with self-rated.. (a) general health, (b) mental health, (c) musculoskeletal pain? Methods: Web-based respondent-driven sampling
Renovation of water and central heating pipelines is a very costly and time-consuming process, so a way to prioritize the limited resources between different parts of the systems is very important. The risk for corrosion damage can be assessed from the resistivity of the ground, due to the processes facilitating the metal oxidation also affecting the resistivity, but galvanic resistivity mapping i
The objective was to describe the epidemiology, bacteriology, clinical presentation, risk factors for endocarditis (IE), diagnostic workup, and outcome of patients with bacteremia caused by the non-influenzae Haemophilus, Aggregatibacter, Cardiobacterium, Eikenella, and Kingella genera (HACEK). A retrospective population-based cohort of patients with bacteremia collected from 2012 to 2017 was iden
The cytoskeleton plays a key role in establishing robust cell shape. In animals, it is well established that cell shape can also influence cytoskeletal organization. Cytoskeletal proteins are well conserved between animal and plant kingdoms; nevertheless, because plant cells exhibit major structural differences to animal cells, the question arises whether the plant cytoskeleton also responds to ge
Background and purpose — Indication for lumbar disc herniation (LDH) surgery is usually to relieve sciatica. We evaluated whether back pain also decreases after LDH surgery. Patients and methods — In the Swedish register for spinal surgery (SweSpine) we identified 14,097 patients aged 20–64 years, with pre- and postoperative data, who in 2000–2016 had LDH surgery. We calculated 1-year improvement
Deep eutectic solvents (DES) are potentially greener solvents obtained through the complexation of simple precursors which, among other applications, have been investigated in recent years for their ability to support the self-assembly of amphiphilic molecules. It is crucial to understand the factors which influence surfactant solubility and self-assembly with respect to the interaction of the sur
Abstract SummaryIn the late 1920s, Åke Gustafsson and Herman Nilsson-Ehle started experiments of induced mutations at the Svalöf Plant Breeding Station in Sweden. Already in the mid-1930s, the first viable mutations appeared, and in 1940 an extended research program was set up. Gustafsson devoted much of his scientific career to mutation research. With funding granted by the Swedish government, he
