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Long term evaluation of pain, sexual discomfort, and comparison of pain assessment scales after inguinal hernia surgery

Abstract:Background:Chronic postoperative inguinal pain (CPIP) affecting daily activities is reported in 8-12% and moresevere pain between 0.6-6% after inguinal hernia repair. CPIP incidences are based on a variety ofPROMs and definitions of pain, making comparison between studies difficult. Pain during sexualactivity (SEX-P) is rarely studied in randomized settings. Few RCTs with large cohorts re

Running on empty: Gender, time allocation, and daily stress experience across the life course

Stress is a public health concern. One of the explanations to why women, more than men, receive stress-related diagnosis in connection to sickness absence is their responsibility for housework and caregiving. We investigate men’s and women’s time allocation and its association with everyday stress across life course stages (25-74 years), using individual time diary data (N=11,880) from the 2000/01

Maternal diet in pregnancy and the risk of inflammatory bowel disease in the offspring: a prospective cohort study

BackgroundDiet has been hypothesized as a risk factor for the development of inflammatory bowel disease (IBD).ObjectiveThe objective of this study was to explore associations between maternal diet diversity and quality in pregnancy and the offspring’s risk of IBD.MethodsWe used data from a nationwide cohort study on 85,129 Norwegian children followed from birth (1999–2009) with information on mate

Top-Down Methods for Estimating the European Carbon Budget : Towards Independent Monitoring and Verification of Carbon Emissions

This thesis investigates the role of advanced atmospheric inversion techniques and ∆¹⁴CO₂ observations in improving the accuracy of regional CO₂ flux estimates across Europe. Accurate quantification of fossil fuel emissions and biospheric fluxes is essential for understanding regional carbon budgets and supporting climate policy. However, significant uncertainties persist due to limited observatio

Fragrance Contact Allergy – A Review Focusing on Patch Testing

Fragrance materials are widely used in various types of products in daily life and many of them can be contact sensitizers. Contact allergy to fragrances has been reported to be common worldwide. Unlike other groups of contact allergens such as metals and preser-vatives, fragrance materials in consumer products can be present as single fragrance chemicals or in the form of mixtures known as natura

Multiplex genome editing eliminates lactate production without impacting growth rate in mammalian cells

The Warburg effect, which describes the fermentation of glucose to lactate even in the presence of oxygen, is ubiquitous in proliferative mammalian cells, including cancer cells, but poses challenges for biopharmaceutical production as lactate accumulation inhibits cell growth and protein production. Previous efforts to eliminate lactate production in cells for bioprocessing have failed as lactate