Från mars -79Trött på alla som kom med ord, ord men inget språk for jag till den snötäckta ön.Det vilda har inga ord.De oskrivna sidorna breder ut sig åt alla håll!Jag stöter på spåren av rådjursklövar i snön. Språk men inget ord.(Tomas Tranströmer)Pedagogisk forskning kännetecknas av att fokusera på processer och relationer i förändring. För att metodologiskt undersöka dessa har vi som forskare u

Syfte är att belysa posthumanistiska perspektiv i pedagogisk forskning. Vi vill med vidga förståelsen för den förskjutning som de senaste åren har skett från poststrukturalism till posthumanism. Det har bl. a inneburit att forskningsintresset flyttas från språk till materia och andra icke-mänskliga företeelser. Vad innebär denna ontologiska vändning för synen på språket? Hur tänker vi kring subjek

Salivary proteins modulate bacterial colonization in the oral cavity and interact with systemic pathogens that pass through the oropharynx. An interesting example is the opportunistic respiratory pathogen Streptococcus pneumoniae that normally resides in the nasopharynx, but belongs to the greater Mitis group of streptococci, most of which colonize the oral cavity. Streptococcus pneumoniae also ex

BACKGROUND: To minimize the risk of pneumonia, many anesthesiologists delay anesthesia-requiring procedures when patients exhibit signs of viral upper respiratory tract infection. Postinfluenza secondary bacterial pneumonias (SBPs) are a major cause of morbidity and mortality. An increased host susceptibility to SBP postinfluenza has been attributed to physical damage to the pulmonary epithelium,

Given the rise of antibiotic resistance and other difficult-to-treat diseases, genetic vaccination is a promising preventative approach that can be tailored and scaled according to the vector chosen for gene delivery. However, most vectors currently utilized rely on ubiquitous delivery mechanisms that ineffectively target important immune effectors such as antigen presenting cells (APCs). As such,

Streptococcus pneumoniae is a leading cause of infectious disease globally. Nasopharyngeal colonization occurs in biofilms and precedes infection. Prior studies have indicated that biofilm-derived pneumococci are avirulent. However, influenza A virus (IAV) infection releases virulent pneumococci from biofilms in vitro and in vivo. Triggers of dispersal include IAV-induced changes in the nasopharyn

Lyxkonsumtion, Stureplansbrats, medelklass och överklass diskuteras allt mer. Samtidigt har den partipolitiska borgerligheten tagit över regeringsmakten. Men vad innebär det att tala om borgerlighet i dagens Sverige? Vilka tillhör denna sociala kategori och vad utmärker den? I Fronesis nr 24 dissekeras gårdagens såväl som dagens borgerlighet.

Mer än halva mänskligheten bor nu i städer. I Fronesis nr 18 granskas stadens roll i en globaliserad kapitalism, och dess roll för flödena av människor och ekonomiska värden. Det handlar om framväxten av en nyliberal stadspolitik, byggd på nya klass- och könsorättvisor, nya gränser och kontroll.Den nyliberala staden och dess alternativI år beräknas världens stadsbefolkning överskrida antalet männi

Genetic vaccines offer a treatment opportunity based upon successful gene delivery to specific immune cell modulators. Driving the process is the vector chosen for gene cargo packaging and subsequent delivery to antigen-presenting cells (APCs) capable of triggering an immune cascade. As such, the delivery process must successfully navigate a series of requirements and obstacles associated with the

Membrane depolarization and ion fluxes are events that have been studied extensively in biological systems due to their ability to profoundly impact cellular functions, including energetics and signal transductions. While both fluorescent and electrophysiological methods, including electrode usage and patch-clamping, have been well developed for measuring these events in eukaryotic cells, methodol

BACKGROUND: Group A streptococcus (GAS) commonly colonizes the oropharynx and nonintact skin. However, colonization has been little studied and the role of biofilm formation is unclear, as biofilm experiments to date have not been conducted under conditions that mimic the host environment.METHODS: In this study we grew GAS biofilms on human keratinocytes under various environmental conditions and

BAMLET (Bovine Alpha-lactalbumin Made LEthal to Tumors) is a member of the family of the HAMLET-like complexes, a novel class of protein-based anti-cancer complexes that incorporate oleic acid and deliver it to cancer cells. Small angle X-ray scattering (SAXS) was performed on the complex at pH 12, examining the high pH structure as a function of oleic acid added. The SAXS data for BAMLET species

Both Streptococcus pyogenes and Streptococcus pneumoniae are widely thought to rapidly die outside the human host, losing infectivity following desiccation in the environment. However, to date, all literature investigating the infectivity of desiccated streptococci has used broth-grown, planktonic populations. In this study, we examined the impact of biofilm formation on environmental survival of