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LES of Supersonic Combustion in a Mach 2 Cavity-Based Model Scramjet Combustor with Conjugate Heat Transfer and Radiative Heat Transfer

Here we report on reactive Large Eddy Simulations (LES) of flow and combustion in the US Air Force Research Laboratory Research Cell 19 cavity-based scramjet combustor. This case involves combustion of ethylene (C2H4) injected into a cavity from its slanted trailing edge. It has previously been studied experimentally with multiple techniques including particle image velocimetry, shadowgrapy, OH pl

Plants as biofactories for production of the aphid sex pheromone nepetalactone

Aphids cause massive agricultural losses through direct damage or as pathogen vectors. Control often relies on insecticides, which are expensive and not selective. An interesting alternative is to use aphid sex pheromones nepetalactone (NON) and nepetalactol (NOL) to interfere with aphid mating or attract aphid predators. Here, we explore production of these compounds in plants, as their precursor

Heard But Not Seen—Swedish Opera Choristers’ Thoughts on Occupational Environment and Vocal Health, an Explorative Qualitative Study

Objective: Professional operatic singing is vocally demanding, making the maintenance of professional vocal health a paramount concern for the opera chorister. Occupational environment has been shown to affect vocal health for other vocally dependent professions. Hence, the objective of the current study was to explore what occupational environment factors affect the professional vocal health of S

Proportion of acceptable symptom state nearly tripled with improvements in patient-reported outcomes for all symptom state subgroups : A registry study of over 15,000 osteoarthritis patients in a digital education and exercise therapy

OBJECTIVE: This study investigated trajectories of patient acceptable symptom state (PASS) among participants of a digital education and exercise therapy for knee and hip osteoarthritis.METHODS: A longitudinal observational study among individuals aged 40+ years who participated in the digital program. Participants completed PASS (yes/no) at enrolment and at least one follow-up during one year aft

The Memory and Affective Flexibility Task : a new behavioral tool to assess neurocognitive processes implicated in emotion-related impulsivity and internalizing symptoms

Background: Cognitive rigidity and working memory impairment are established features of internalizing syndromes. Growing evidence suggests that deficits in affective control –cognitive control in the context of emotion – may underpin elevated emotion-related impulsivity in various psychiatric disorders. Objective: This study examines two components of affective control (affective flexibility and

Lack of ST2 aggravates glioma invasiveness, vascular abnormality, and immune suppression

Background. Glioblastoma (GBM) is the most common primary malignant brain tumor in adults, characterized by aggressive growth and a dismal prognosis. Interleukin-33 (IL-33) and its receptor ST2 have emerged as regulators of glioma growth, but their exact function in tumorigenesis has not been deciphered. Indeed, previous studies on IL-33 in cancer have yielded somewhat opposing results as to wheth

Comparative safety and efficacy of new-generation single-layer polytetrafluorethylene- versus polyurethane-covered stents in patients with coronary artery perforation for the RECOVER (REsults after percutaneous interventions with COVERed stents) Investigators

New-generation single-layer polytetrafluorethylene (PTFE-) or polyurethane (PU-) covered stent (CS) for the treatment of coronary artery perforation (CAP) during PCI offer high procedural efficacy. To evaluate the comparative long-term safety and efficacy of both devices. This is a multicenter pooled analysis of individual data of patients with CAP undergoing implantation of single-layer PTFE-CS o

The Impact of Witnessing School Bullying in the Classroom : Exploring Perceptions and Responses Among Turkish Students

This study addresses the impact of witnessing different types of school bullying on Turkish school students who are bystanders. The primary aim is to investigate how the type of bullying (direct/indirect; ostracism/devaluation) affects the perception of bullying and the roles witnesses take. Additionally, we explore whether gender, global state self-esteem, and identification with one’s school acc

Grassroots innovations in agriculture innovation systems : insights into seabuckthorn (Hippophae rhamnoides) in Ladakh, India

Purpose: Agriculture innovation systems (AIS) examine the complex socio-technical and institutional aspects affecting sustainable agriculture. However, it is predominantly constrained to the formal sector activities in the high-income countries (HICs). The informal sector actors play a major role in the agricultural sector of low- and middle-income countries (LMICs), such as India, by innovating a

Heavy and super-heavy nuclei and elements : production and properties: Editorial preface to the topical collection

The advances in understanding and producing heavy and super-heavy elements is the subject of this topical collection. The main covered subjects are: the description of the theory, developments of super-heavies and the determination of the Island of Stability as well as the role of these nuclei as part of the r-process scenario. The accurate determination of reaction processes are crucial to enable

Improving the effectiveness of climate change adaptation measures

To a large degree, economic metrics and mechanisms underpin the design of adaptation policies. Such a focus has undesired consequences on the effectiveness of adaptation measures as well as on our ability to prevent incommensurable losses. The article puts forward four strategic changes in adaptation policy that shift the focus away from markets and toward community-level visions of what a liveabl

Using statistical analysis and pollution indices to characterize metal pollution in volcanic and calcareous soils in semi-arid regions

The main objective of this study was to evaluate heavy metal contamination in volcanic and calcareous soils within Morocco’s semi-arid regions, focusing on the relationship between unique soil types and contamination dynamics. Using geographic information systems (GIS), statistical analyses, and several pollution indices, including the geoaccumulation index (Igeo), enrichment factor (EF), contamin

Probabilistic Distributions of Moisture Damages in Swedish Buildings

Moisture damages lead to significant costs and impact indoor environments negatively. Identifying their occurrence patterns is crucial for the implementation of preventive or mitigative measures, though it remains highly challenging due to the complex interplay of multidimensional variables. This study aims to identify primary moisture damage profiles in Swedish buildings and evaluate their preval

Pediatric spinal high-grade glioma in the pediatric precision oncology registry INFORM : Identification of potential therapeutic targets

Background: High-grade glioma (HGG) of the spinal cord constitutes rare tumors in the pediatric population. Knowledge of the molecular profile of this pediatric HGG (pedHGG) subgroup is limited and the clinical outcome is poor. Therefore, the aim of this study is to provide more profound investigations of molecular characteristics and clinical features of these tumors. Methods: Between January 201

Survey of legislative frameworks and national recommendations governing paediatric maintenance haemodialysis in Europe

Background: The application of international recommendations for paediatric maintenance haemodialysis (HD) could be strengthened by national laws or written recommendations. Our aim was therefore to describe the national rules governing paediatric maintenance HD in European countries. Methods: A national representative, approved by the president of each paediatric nephrology society, was contacted

Can response to ADHD medication be predicted?

Predictors for the pharmacological effect of ADHD medication in children and adolescents are lacking. This study examined clinically relevant factors in a large (N = 638) prospective cohort reflecting real-world evidence. Children and adolescents aged 6–17 diagnosed with ADHD were evaluated at baseline and three months following ADHD medication initiation. The outcome was measured as a reduction i