Purpose: A substantial proportion of amyloid-β (Aβ)+ patients with clinically diagnosed Alzheimer’s disease (AD) dementia and mild cognitive impairment (MCI) are tau PET–negative, while some clinically diagnosed non-AD neurodegenerative disorder (non-AD) patients or cognitively unimpaired (CU) subjects are tau PET–positive. We investigated which demographic, clinical, genetic, and imaging variable

In the present study, large-eddy simulations (LES) are used to identify the underlying mechanism that governs the ignition phenomena of spray flames from different nozzle diameters when the ambient temperature (T am) varies. Two nozzle sizes of 90μm and 186μm are chosen. They correspond to the nozzle sizes used by Spray A and Spray D, respectively, in the Engine Combustion Network. LES studies of

In this chapter, the author argues that the old-school confessional and ethnocentric theology has no place in today’s Western secular academia. He focuses on the academic discipline under the name “theology”. Mission studies has represented a widening of the horizon in theology in the sense that through it, non-Western cultures and religions have gradually been introduced into the theological agen

The environment that parents experience can influence their reproductive output and their offspring's fitness via parental effects. Perceived predation risk can affect both parent and offspring phenotype, but it remains unclear to what extent offspring behavioral traits are affected when the mother is exposed to predation risk. This is particularly unclear in live-bearing species where maternal ef

The aim of this study was to explore the influence of social ideologies on the doing, being, becoming, and belonging of Western employed professional women who are new mothers, after returning to work outside the home within the first 18 months after giving birth. Although occupational science has provided valuable insights into mothering occupations, it perpetuates an individualistic focus that o

The notion of “contextual theology” has a long history, beginning with its gradual introduction in the “Fund for Theological Education”. Theology takes place as doing theology within contexts. A significant criterion for differentiating between, for example, contextual and constructive theology seems to lie in the valuation of how suffering, violence, and the struggle for social and environmental

This book advances that history by exploring stories, images and discourses across a worldwide range of geographical, cultural and confessional contexts. Its twelve authors not only enrich our understanding of the significance of the contextual method, but also produce a new range of original ways of doing theology in contemporary situations. The authors discuss some prioritised thematic perspecti

Objectives: Systemic lupus erythematosus (SLE) is an autoimmune disease with extensive heterogeneity in disease presentation between patients, which is likely due to an underlying molecular diversity. Here, we aimed at elucidating the genetic aetiology of SLE from the immunity pathway level to the single variant level, and stratify patients with SLE into distinguishable molecular subgroups, which

If genome sequencing is performed in health care, in theory the opportunity arises to take a further look at the data: opportunistic genomic screening (OGS). The European Society of Human Genetics (ESHG) in 2013 recommended that genome analysis should be restricted to the original health problem at least for the time being. Other organizations have argued that ‘actionable’ genetic variants should

Importance: Accurate and up-to-date estimates on incidence, prevalence, mortality, and disability-adjusted life-years (burden) of neurological disorders are the backbone of evidence-based health care planning and resource allocation for these disorders. It appears that no such estimates have been reported at the state level for the US. Objective: To present burden estimates of major neurological d

Purpose: Practicing geriatric medicine is a challenging task since it involves working together with other medical doctors while coordinating a multidisciplinary team. Global Europe Initiative (GEI) group within the European Geriatric Medicine Society gathers geriatricians from different regions where geriatrics is underrepresented or still developing to promote initiatives for the advancement of

Plants release to the atmosphere reactive gases, so-called volatile organic compounds (VOCs). The release of VOCs from vegetation is temperature-dependent and controlled by vegetation composition because different plant species release a distinct blend of VOCs. We used modelling approaches on ecosystem VOC release data collected across the Arctic, which is experiencing both rapid warming and veget

The financial crisis of 2008 resulted, among other, on a popular awareness that the monetary system was not working for the interest of the many. The blockchain technology that was launched soon after offered monetary activists and entrepreneurs a tool to re-imagine, re-claim and re-organize money along a vague ideal of a commons paradigm. A wave of monetary experimentation ensued that took a most

A game that brings to life the challenges that community currencies aim to address, its various designs and communities various responses to them.