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Prevalence of dermatitis including allergic contact dermatitis from medical devices used by children and adults with Type 1 diabetes mellitus : A systematic review and questionnaire study

Use of medical devices (MDs), that is, glucose sensors and insulin pumps, in patients with Type 1 diabetes mellitus (T1D) has proven an enormous advantage for disease control. Adverse skin reactions from these MDs may however hamper compliance. The objective of this study was to systematically review and analyse studies assessing the prevalence and incidence of dermatitis, including allergic conta

Subtropical forest macro-decomposers rapidly transfer litter carbon and nitrogen into soil mineral-associated organic matter

Background: Forest soils in tropical and subtropical areas store a significant amount of carbon. Recent frameworks to assess soil organic matter (SOM) dynamics under evolving global conditions suggest that dividing bulk SOM into particulate and mineral-associated organic matter (POM vs. MAOM) is a promising method for identifying how SOM contributes to reducing global warming. Soil macrofauna, ear

Pencil beam scanning proton therapy for mediastinal lymphomas in deep inspiration breath-hold : a retrospective assessment of plan robustness

PURPOSE/BACKGROUND: The aim of this study was to evaluate pencil beam scanning (PBS) proton therapy (PT) in deep inspiration breath-hold (DIBH) for mediastinal lymphoma patients, by retrospectively evaluating plan robustness to the clinical target volume (CTV) and organs at risk (OARs) on repeated CT images acquired throughout treatment. Methods: Sixteen mediastinal lymphoma patients treated with

Neutron diffraction from a microgravity-grown crystal reveals the active site hydrogens of the internal aldimine form of tryptophan synthase

Pyridoxal 5′-phosphate (PLP), the biologically active form of vitamin B6, is an essential cofactor in many biosynthetic pathways. The emergence of PLP-dependent enzymes as drug targets and biocatalysts, such as tryptophan synthase (TS), has underlined the demand to understand PLP-dependent catalysis and reaction specificity. The ability of neutron diffraction to resolve the positions of hydrogen a

Operando study of HfO2 atomic layer deposition on partially hydroxylated Si(111)

The introduction of atomic layer deposition (ALD), to the microelectronics industry has introduced a large number of new possible materials able to be deposited in layers with atomic thickness control. One such material is the high-κ oxide HfO2; thermally stable and ultrathin HfO2 films deposited by ALD are a significant contender to replace SiO2 as the gate oxide in capacitor applications. We pre

Development of combined operando diagnostics : Applications in heterogeneous catalysis and electrochemistry

With the aim to bridge the pressure gap between traditional surface science and industrial applications, heterogeneous catalytic reactions on model catalysts are increasingly studied at near-ambient pressures. Under those conditions, the gas phase has been shown to play an important role during the interaction at the gas-surface interface making it complex to study. This complexity can be capturedWith the aim to bridge the pressure gap between traditional surface science and industrial applications, heterogeneous catalytic reactions on model catalysts are increasingly studied at near-ambient pressures. Under those conditions, the gas phase has been shown to play an important role during the interaction at the gas-surface interface making it complex to study. This complexity can be captured

Development of a novel AAK1 inhibitor via Kinobeads-based screening

A chemical proteomics approach using Ca2+/calmodulin-dependent protein kinase kinase (CaMKK) inhibitor–immobilized sepharose (TIM-063-Kinobeads) identified main targets such as CaMKKα/1 and β/2, and potential off-target kinases, including AP2-associated protein kinase 1 (AAK1), as TIM-063 interactants. Because TIM-063 interacted with the AAK1 catalytic domain and inhibited its enzymatic activity m

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I Danmark reguleres det sociale område i høj grad af rammelovgivning, som uddelegerer myndighed, regulerer gennem formålsbeskrivelser og gør det muligt for såkaldte velfærdsprofessionelle at udøve skøn. Denne artikel undersøger, hvordan samspillet mellem velfærdsprofessionelles opfattelser og de ting, der på forskellig vis regulerer deres praksis, får betydning for konstruktionen af legalitet i de

A perceptual learning approach to the Whorfian hypothesis : Supervised classification of motion

Recent research on the relationship between grammatical aspect and motion event cognition has shown that speakers of nonaspect languages (e.g., German, Swedish) attend to event endpoints more than speakers of aspect languages (e.g., English, Spanish). In this study, we took a perceptual learning approach to the Whorfian hypothesis, training native English speakers to categorize events either in an

Second language influence on first language motion event encoding and categorization in Spanish-speaking children learning L2 English

Studies show cross-linguistic differences in motion event encoding, such that English speakers preferentially encode manner of motion more than Spanish speakers, who preferentially encode path of motion. Focusing on native Spanish speaking children (aged 5;00–9;00) learning L2 English, we studied path and manner verb preferences during descriptions of motion stimuli, and tested the linguistic rela