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BACKGROUND: Renal glomerular filtration rate (GFR) of pediatric cancer patients at diagnosis has previously been investigated in a limited number of studies. PROCEDURE: GFR, measured by iohexol clearance, was prospectively investigated in 55 children over the age of 1 year with malignancies, (group A). Elevated GFR (>175 ml/min/1.73 m(2)) at diagnosis was found. To investigate if this finding was
OBJECTIVE: To study muscle strength and functional performance in patients with anterior cruciate ligament (ACL) injury with or without surgical reconstruction 2 to 5 years after injury. Good muscle function is important in preventing early-onset osteoarthritis (OA), but the role of reconstructive surgery in restoring muscle function is unclear. METHODS: Of 121 patients with ACL injury included in
OBJECTIVE: To compare ambulatory blood pressure recorded during a work day with a leisure day regarding masked hypertension. DESIGN: A randomized crossover study in middle-aged normotensives. PARTICIPANTS: Thirty-seven untreated middle-aged normotensives (17 women), who had repeated office blood pressure less than 140/90 mmHg. MAIN OUTCOME MEASURE: Individual difference of masked hypertension betw
Preeclampsia is a pregnancy-related disease afflicting 3-7% of pregnancies worldwide and leads to maternal and infant morbidity and mortality. The disease is of placental origin and is commonly described as a disease of two stages. A variety of preeclampsia animal models have been proposed, but all of them have limitations in fully recapitulating the human disease. Based on the research question a
The overall aim of this study was to survey and analyze the selection process for patients awaiting a kidney in the Nordic countries collaborating within Scandiatransplant.
Annual and seasonal variations in surface air temperature (SAT) during the period 1961–2011 were analysed using daily mean temperature data sets from regular grid points (10?×?10?km2) throughout Finland. The Mann–Kendall nonparametric test was used to detect significant historical trends in SAT and Spearman's correlation coefficient (?) to test the relationships between SAT patterns and various at
Abstract is not available
Targeting mechanisms of neutrophil elastase (NE) and other luminal proteins stored in myeloperoxidase (MPO)-positive secretory lysosomes/primary granules of neutrophils are unknown. These granules contain an integral membrane protein, CD63 with an adaptor protein-3-dependent granule delivery system. Therefore, we hypothesized that CD63 cooperates in granule delivery of the precursor of NE (proNE).
Fuel cells are promising due to advantages with higher energy conversion efficiency and lower emissions of SOX, NOX and CO2 than conventional power systems. Solid oxide fuel cell (SOFC) is a high temperature fuel cell, which operates at 600-1000 ºC. The high operating temperature and the anode material allow SOFCs to operate with different types of fuels from both fossil and renewable sources due
Flint was the most widely employed raw material for artifact manufacture in Denmark and Sweden during the Stone Age, and it continued to be used during subsequent periods. Prehistoric flint mining and lithic manufacturing studies in these countries have attracted considerable attention, but there have been no recent attempts to chemically characterize the geologic source materials. This paper buil
Sacrococcygeal teratoma (SCT) is a rare congenital tumor associated with high rates of perinatal mortality and morbidity. This study evaluated the incidence, prenatal detection rate, and early predictors of a complicated outcome following diagnosis of SCT.
The temporomandibular joint is critical for jaw movements and allows for mastication, digestion of food, and speech. Temporomandibular joint osteoarthritis is a degenerative disease that is marked by permanent cartilage destruction and loss of extracellular matrix (ECM). To understand how the ECM regulates mandibular condylar chondrocyte (MCC) differentiation and function, we used a genetic mouse
PURPOSE To evaluate the early treatment response in children with acute myeloid leukemia (AML) using a response-guided induction strategy that includes idarubicin in the first course. PATIENTS AND METHODS All Nordic children with AML younger than 15 years (n = 151) were treated on the Nordic Society for Pediatric Hematology and Oncology (NOPHO) AML 2004 protocol. After the first course of idarubic
As the presence of English in Europe continues to grow, there is a mounting interest in the position of national languages among European institutions, societies, and people. Swedish, like many national languages in Europe and throughout the world, is in an awkward position. It is at the same time a strong national language with the potential to dominate other languages within national borders and
