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Early- versus Late-onset Alzheimer’s Disease—3-year Outcomes of Cholinesterase Inhibitor Treatment in Routine Clinical Practice.

Background: Alzheimer’s disease (AD) is an insidiously progressive neurodegenerative disorder that is characterized by multiple cognitive impairments and gradual loss of independence in carrying out activities of daily living (ADL). Currently, the predominant therapy for mild-to-moderate AD is cholinesterase inhibitors (ChEIs), which have been shown to have positive effects on symptoms compared wi

European Spallation Source Lattice Design Status

The accelerator of the European Spallation Source (ESS) will deliver 62.5 mA proton beam of 2.0 GeV onto the target, offering an unprecedented beam power of 5 MW. Since the technical design report (TDR) was published in 2013, work has continued to further optimise the accelerator design. We report on the advancements in lattice design optimisations after the TDR to improve performance and flexibil

Gender and Use of Space

The use of public space is an important part of women’s and men’s daily lives in cities and an important arena to promote social inclusion in cities. Public space consists of places for social encounter and exchange, places for political action and participation in public life and plays an important role as places for economic activities. This paper presents a case study of a neighbourhood in San

Packaging development in a core production perspective - a case study at Volvo Cars

Business success is the result of focusing enhancement of the total performance of the supply network. While all products need packaging in different stages in the supply network, packaging producers deliver into a “core” network. Thus they are seldom an integrated actor of the core supply network. Consequently, the more the package and product development can be functionally combined, and integra

Epistemic Risk : Issues on the normative basis of risk analysis

The articles included in this thesis centre on what can be called the normative basis of risk analysis. Since risk analyses are decision procedures, they should adhere to norms of rational decision-making, and this they do. Most risk analysis schemes are built on a notion of the decision theoretic maxim that the goal of every decision is to maximize expected utility. However, for some thirty years