Investigating the role of miRNAs in Glucose-Stimulated Insulin Secretion MicroRNAs have emerged as important players in many aspects of fundamental biological processes including regulation of pancreatic β-cell functions. Failure in beta cell functions, specifically with regards to glucose-stimulated insulin secretion (GSIS), contributes in the pathogenesis of type-2 diabetes (T2D). Previous stud

Molecular cluster is a nanoparticle that is defined as an agglomerate of few up to 106-7 of molecules (corresponding to 1- 100 nm in size) that can be manipulated by the cluster beams. Molecular cluster properties typically lie between the individual molecule and bulk matter properties. This work describes the employment of the Cold Aerodynamic Source (CAS) to produce a narrow, collimated and iso

The company QB Food Tech designs and installs powder in liquid mixing systems for the food and pharmaceutical industries. The aim of this master thesis is to develop a continuous blending system with concentration output feedback for inline blending of complex products starting from an existing batch process. A method for measuring a substance concentration in flow‐rates therefore needs to be esta

The objective for this master thesis has been to develop a mathematical model of the actuator parts of the fifth generation Haldex AWD system. The parts to be modeled are the DC-Machine and the pump. Also a model of the elasticity of the clutch has to be derived as well as a model for the hydraulic fluid. These models were then to be implemented in Matlab Simulink. The model was derived by means o

As fossil based fuels are ever more proving to be an unsustainable energy-resource, it is of critical importance to find a new way to deliver power to the worlds vehicles in order to anticipate an ever-growing population and sustain economic growth. The task is complicated but very achievable from a technological point of view. It is however greatly overshadowed in complexity when it comes to educ

The Division of Industrial Electrical Engineering and Automation, IEA, at LTH is participating in the research project DLAB, sponsored by E.ON. The goal of this project is to gain more understanding of the problems arising from increased cablification of Swedish medium voltage distribution grid and to develop an electric power laboratory. More and longer cables have increased the capacitive earth

Abstract: Avian long-distance migration as an adaptation to spatiotemporally changing resources is a complex evolutionary trait shaped by various endo- and exogenous factors. Descriptive studies of migratory journeys provide direct investigations of migratory parameters and these often set the basis for fun-damental follow-up studies on the eco-evolutionary principles. In this study, male Great

Today, many projects about Electric Vehicles (EVs) and Hybrid Electric Vehicles (HEVs) are in progress within the automotive industry. Fuel-efficiency and reduction of carbon dioxide emissions from vehicles are the main targets. This thesis is within in one of these projects that is called electric All Wheel Drive(eAWD) at BorgWarner TorqTransfer Systems AB. A key parameter to perform an accurate

This master thesis is written at the division of Industrial Electrical Engineering and Automation (IEA) Lund University, Faculty of Engineering, in cooperation with AB Regin in Landskrona. AB Regin wishes to determine whether their existing controller platforms can be used to implement a control system for boilers. The control system should be flexible in terms of boiler size, boiler fuel and boil

Varför vill duvan hellre falla än flyga? Under lång tid använde vi endast vår kunskap om flygplan för att förstå hur fåglar, fladdermöss och insekter kan flyga. Detta trots det är tydligt att de stela flygplansvingarna inte liknar till exempel fladdermössens mjuka embranvingar särskilt mycket. Tänk bortom klassisk flygplansaerodynamik, och du kan lära dig mycket om alla de speciella flygtekniker ABSTRACT Among small to medium-sized birds, intermittent flight is a common behavior, where pauses are inserted between wingbeats. This is believed to have the effect of changing the power output without having to change the wingbeat frequency. Small birds often perform bounding flight, where the wings are completely folded against the body during pauses, while larger birds can be found to glide

This masters thesis presents a development of a software to analyse and evaluate a rotary mechatronic demonstration rig. Most of the hardware existed and the task was to develop software in Excel and PLC Ladder to detect dierences between the different setups in a mechatronic system. The software is supposed to be used for educational purposes on Tetra Pak and should thereby be easy to use and giv

Abstract Background – The ability to generate induced pluripotent stem cells-derived cardiomyocytes (iPSC-CM) has raised much expectation for treatment of myocardial infarction as a stem cell based therapy. In the present study we aimed to evaluate the ability of iPSC-CM production in vitro from three fibroblast sources and verify if there is inter-clonal or inter-source variance. Methods and Res

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Haldex Traction can with their Active Yaw Control prevent unwanted handling by applying an extra yaw torque with their all wheel drive system. To be able to calculate when or when not, yaw torque should be applied, it is important to accurate know the different state information about the vehicle. When driving on banked roads, vehicle dynamics and sensor measurements are changed compared to drivin

The acknowledgement that mankind has a limited amount of resources in energy and a growing demand, joined with the awareness of the environmental impact of an only fuel-based electricity production have led to the expansion and democratization of renewable and green energies. The wind electricity production nowadays exists under various forms, differing one from another by their size, their mechan

Wind turbines are often used on weak grids as a source of active power. There is a desire for a continuous supply of active power during variable wind speeds while also supplying reactive power to suppress grid-voltage fluctuations. These objectives are attainable using converters which are controlled with regulators. In this project a test environment will be constructed wherein a wind turbine wi

Syftet med detta arbete är att utreda markanvändningens kolinlagringsförmåga i Örebro kommun och vilka konsekvenser olika typer av markanvändning kan få för klimatet. Detta för att undersöka möjligheten att inkludera markanvändningssektorn i kommunens nästa klimatplan. Resultatet visar att kolinlagringsförmågan för Örebro kommuns marker (exklusive sjöar och våtmarker) idag är 8 230 ton C/år. Om dThe purpose of this thesis is to investigate the current carbon storage in the land-use sector in Örebro municipality and which consequences different land-uses have on the climate. The municipality wants to investigate the possibility to include the land-use sector in the next climateplan. This study has found that the carbon storage for ground and vegetation in Örebro municipality (exclusive o

Popular science summary: Do bacteria survive in humans by eating the defense molecules during the course of infection? Enterococcus faecalis (E. faecalis) is a pathogen that can be found in the human gut which causes a wide range of infections including urinary tract infections, cardiovascular infections and bacteremia (presence of bacterial cells in blood stream). These bacteria can also be fou

Abstract Non-coding RNAs (ncRNAs) are involved in many diverse biological functions. In this thesis, my objectives were focused on the functional evaluation of two types of ncRNAs. First, the functional consequences of miR-944 regulation were evaluated in HeLa, a cervical cancer cell line. Results showed a reduced cell proliferation on miR-944 overexpression by using the WST-1 assay. In addition,