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We implement Bayesian model selection and parameter estimation for the case of fractional Brownian motion with measurement noise and a constant drift. The approach is tested on artificial trajectories and shown to make estimates that match well with the underlying true parameters, while for model selection the approach has a preference for simple models when the trajectories are finite. The approa
We have used two-photon Fourier transform spectroscopy to investigate the first singlet excited state (S1) of a prototypical polyene molecule 1,5—Diphenyl-1,3,5-hexatriene. As the S1 state in the polyenes is a one-photon forbidden transition, the structure of its vibrational levels cannot be studied using resonant linear excitation. Although this level is accessible with two-photon excitation, pre
The Øresund Basin in the transnational area between Sweden and Denmark forms a marginal part of the Danish Basin. The structural outline and stratigraphy of the Mesozoic succession is described, and a novel interpretation and description of the subsurface geology and geothermal potential in the North Sjælland Half-graben is presented. The subsurface bedrock in the basin includes several Mesozoic i
Circular RNAs (circRNAs) are a class of RNAs that is under increasing scrutiny, although their functional roles are debated. We analyzed RNA-seq data of 348 primary breast cancers and developed a method to identify circRNAs that does not rely on unmapped reads or known splice junctions. We identified 95,843 circRNAs, of which 20,441 were found recurrently. Of the circRNAs that match exon boundarie
En av de mest växande medicinska problemen i samhället är den allt ökande frakturfrekvensen i befolkningen. Vilka individer som drabbas av en frakturberor på ett samspel mellan en rad olika faktorer som benmassan, skelettarkitekturen, muskelstyrkan, muskelfunktionen, balansen och falltendensen. Det har övertygande visats att fysisk aktivitet kan påverka en rad av dessa riskfaktorer för fraktur. Ök
Om fysisk aktivitet har en roll att spela vid behandlingen av osteoporos utvärderas oftast genom att studera om träning minskar riskfaktorer för uppkomsten av en fraktur, exempelvis om träning ökar benmassan. Emellertid är riskfaktorer bara ersättningsvariabler för den enda egentliga acceptabla effektvariabeln – en fraktur - när träningens effekt skall utvärderas. Det är sålunda först om man kan v
Increased knowledge on familial melanoma and the underlying genetics Approximately 5-10 % of all melanoma patients have close relatives with melanoma. 5-20% of melanoma families have germline mutations in the CDKN2A gene. Swedish CDKN2A mutation carriers have a young median age of onset of melanoma, increased risks of multiple primary melanoma and of tobacco-associated cancers in respiratory and u
The Global Gridded Crop Model Intercomparison (GGCMI) phase 1 dataset of the Agricultural Model Intercomparison and Improvement Project (AgMIP) provides an unprecedentedly large dataset of crop model simulations covering the global ice-free land surface. The dataset consists of annual data fields at a spatial resolution of 0.5 arc-degree longitude and latitude. Fourteen crop modeling groups provid
