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AML/GAS7, resulting from t(11;17)(q23;p13), has been reported in one case of treatment-related acute myeloid leukemia (AML). We present a de novo case of t(11;17)-positive pediatric acute lymphoblastic leukemia. Fluorescent in situ hybridization and reverse transcriptase polymerase chain reaction analyses revealed an MLL/GAS7 chimera identical to the one previously described in AML. The molecular

Encapsulated Haemophilus influenzae is a causative agent of invasive disease, such as meningitis and septicemia. Several interactions exist between H. influenzae and the human host. H. influenzae has been reported to bind IgD in a nonimmune manner, but the responsible protein has not yet been identified. To define the binding site on IgD for H. influenzae, full-length IgD and four chimeric IgDs wi

Using optimal control as a spectroscopic tool we decipher the details of the molecular dynamics of the essential multidimensional excited-state photoisomerization - a fundamental chemical reaction of key importance in biology. Two distinct nuclear motions are identified in addition to the overall bond-twisting motion: Initially, the reaction is dominated by motion perpendicular to the torsion coor

Thiol (SH) groups play a remarkable role in the cell with their redox state affecting the activity and structure of many enzymes, receptors and transcription factors. In the present work, carbon paste electrodes modified with sulfhydryl oxidase (SOX) were prepared. The proposed biosensor was based on the monitoring of the produced peroxide concentration that correlates with the concentration of re

Vart är idrotten på väg? Det är en väsentlig fråga i det sk Landskronaprojektet inom Idrottsvetenskapligt centrum vid Lunds universitet, ICLU. I denna första rapport inom projektet presenteras 17-åriga flickors och pojkars intresse för motion och idrott. Här kartläggs till exempel hur stort intresset är, vilka idrotter de sysslar med, deras föreningsengagemang och inställning till ämnet idrott och

Thirty-three patients with pityriasis rosea were studied with regard to the possible presence of circulating and cutaneously deposited immune complexes. The levels of circulating immune complexes, determined by a solid-phase C1q-binding assay, were not different from those of healthy control individuals. The levels were similar in samples obtained during the initial and during the remission stages

High-spin states in Lu-165 have been investigated by in-beam gamma-ray coincidence spectroscopy using the EUROBALL spectrometer array. Two new excited rotational bands have been discovered with features similar to a previously known triaxial superdeformed band in that nucleus. Comparison of the decay pattern of these bands, in particular the unusually large E2 transition strength from the first ex

If people believe that some property is true of all members of a class such as sofas, then they should also believe that the same property is true of all members of a conjunctively defined subset of that class such as uncomfortable handmade sofas. A series of experiments demonstrated a failure to observe this constraint, leading to what is termed the inverse conjunction fallacy. Not only did peopl

Abstact is not available

Pulsed field gradient NMR diffusometry is a promising tool for investigating structures of porous material through determinations of dynamic displacements of molecules in porous systems. A problem with this approach is the lack of closed analytical expressions for echo-decays in anything but idealized pore geometries. We present here an approach based on calculating the appropriate diffusion propa

Optimal sampling design with nonparametric population modeling offers the opportunity to determine pharma-cokinetic parameters for patients in whom blood sampling is restricted. This approach was compared to a standard individualized modeling method for meropenem pharmacokinetics in febrile neutropenic patients. The population modeling program, nonparametric approach of expectation maximization (N

: presented at the 2003 annual meeting of the Royal Swedish Academy of Engineering Sciences

A new method for noise reduction using spatiotemporal smoothing is presented in this paper. The method is developed especially for reducing the noise that arises when acquiring video sequences with a camera under very dim light conditions. The work is inspired by research on the vision of nocturnal animals and the adaptive spatial and temporal summation that is prevalent in the visual systems of t

A new mesoporous silica structure with cubic Iad symmetry has been synthesized. The structure has very large unit cell dimensions, up to 250 Å in the as-synthesized form and 222 Å after calcination, and the surface area is around 700 m2/g. The syntheses were done according to well-established synthesis conditions with the triblock copolymers Pluronics P103 or P123, except for the addition of NaI t

The basic features of a simple radial position-sensitive detector design, construction and performance, are described in detail in this paper. The electronics and method used to correlate the position information from the spectrum recorded by the detector are presented. Monte Carlo simulations of the performance of the detector embedded in a time of flight analyser show that such an instrument ena

An iterative decoding scheme for woven convolutional codes is presented. It operates in a window sliding over the received sequence. This exploits the nature of convolutional codewords as infinite sequences and reflects the concept of considering convolutional encoding and decoding as a continuous process. The decoder is analyzed in terms of decoding delay and decoding complexity. Its basic buildi

Software applications are of great importance in organisations, and performance of an organisation depends on how hosting of software applications are organised. This thesis deals with the question: Why and how organisations decide on specific sourcing options for software applications hosting. The thesis describes and explains sourcing decision-making processes made in the Swedish Post (MeLo) and