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Eradication of nasopharyngeal carriage of penicillin-non-susceptible Streptococcus pneumoniae-is it possible?

Background: The South Swedish Pneumococcal Intervention Project (SSPIP) was started in 1995 with the aim of limiting the spread of penicillin-non-susceptible pneumococci (PNSP) in Skåne County, Sweden. As part of the SSPIP, eradication therapy with rifampicin in combination with 1 more antibiotic was considered on a social indication after prolonged carriage of 2-3 months. Methods: In this retrosp

Haemophilus influenzae P4 interacts with extracellular matrix proteins promoting adhesion and serum resistance.

Interaction with the extracellular matrix (ECM) is one of the successful colonization strategies employed by non-typeable Haemophilus influenzae (NTHi). Here we identified Haemophilus lipoprotein 4 (P4) as a receptor for ECM proteins. Purified recombinant P4 displayed a high binding affinity for laminin (Kd=9.26 nM) and fibronectin (Kd=10.19 nM), but slightly less to vitronectin (Kd=16.51 nM). A P

How does Modernity Taste? Tomatoes in the Societal Change from Modernity to Late Modernity

The aim of this article is to discuss how changes in tomato food regulation, production and consumption, can be seen as part of a broader societal change from Modernity to Late Modernity. Based on evidence from the Swedish and European food systems we demonstrate how a system, which has been successfully managing development in food production for several decades by stressing rationality, homogene

Survey of the management of pancreatic pseudocysts in Sweden.

Objective . The management of pancreatic pseudocysts varies, based mainly on local traditions, resources and expertise. No prospective, randomized study has been done comparing different approaches to treatment. The aim of the present study was to identify current treatment strategies in Sweden. Material and methods. A questionnaire comprising 12 questions was e-mailed to the surgical departments

Sports and leisure-time physical activity in pregnancy and birth weight: a population-based study.

We examined the association between sports and other leisure-time physical activities during pregnancy and birth weight of babies born after 37 completed weeks of gestation. All Danish-speaking pregnant women attending routine antenatal care at the Department of Obstetrics, Aarhus University Hospital, Denmark, from August 1989 to September 1991 were invited to participate in the study. A total of

Slaps, Punches, Pinches -- But not Violence: Boundary Work in Nursing Homes for the Elderly

The article presents an analysis of boundary work within the context of care for the elderly, where violence appears to be widespread though still relatively unacknowledged. By resorting to certain descriptive – often jocular – modes, the staff designate aggressive acts committed by patients as 'non-violent'. This occurs although intent, responsibility, and injury – all common criteria associated

Det goda seminariet. Om självständighet och lagarbete i den akademiska verkstaden

The research text seminar is generally a cherished element in academic life. Ideally, this is the place for the exchange of high intellectual thoughts in an atmosphere of mutual respect. But the text seminar, if viewed from the perspective of its historical roots in German academia, is also an arena for collective, informal and apprenticeship learning that is today challenged by a much more indivi

Manipulation of BCG vaccine: a double-edged sword.

Mycobacterium bovis Bacillus Calmette-Guérin (BCG), an attenuated vaccine derived from M. bovis, is the only licensed vaccine against tuberculosis (TB). Despite its protection against TB in children, the protective efficacy in pulmonary TB is variable in adolescents and adults. In spite of the current knowledge of molecular biology, immunology and cell biology, infectious diseases such as TB and H