Some human bacterial pathogens produce specific immunoglobulin A1 (IgA1) proteases that cleave the heavy chain of human IgA1, generating intact Fab and Fc fragments. Other pathogenic bacterial species express surface proteins which bind to the Fc part of human IgA in a non-immune manner. To analyse whether IgA-binding proteins affect the activity of IgA1 proteases, the ability of seven different I

Investigations of variations in metabolic efficiency and thermogenesis have a short and turbulent history. In small animals, non-shivering thermogenesis and diet-induced thermogenesis have a great impact on overall body weight, and the question is whether mechanisms to waste energy have evolved also in human energy metabolism. The candidate molecules for this adaptive thermogenesis are the uncoupl

The Homogeneous Charge Compression Ignition (HCCI) is the third alternative for combustion in the reciprocating engine. Here a homogeneous charge is used as in a spark-ignited engine, but the charge is compressed to autoignition as in a diesel. The main difference compared with the Spark Ignition (SI) engine is the lack of flame propagation and hence the independence from turbulence. Compared with

A breast cancer-associated mRNA originally cloned as a 475-bp partial cDNA from a library enriched for tumour cDNAs [Oncogene 16 (1998) 327] is expressed at high levels in breast and prostate cancer cells. Immunohistochemical analysis indicates that the protein is expressed in primary breast tumours. We used RT-PCR to generate a full-length 2852 nt mRNA sequence that includes the hypothetical open

Cleavage of P=Se bonds occurs readily in the room-temperature treatment of [Os-3(CO) (10)(MeCN)(2)] with Ph3P=Se to give three new compounds, [Os-3(mu(3)-Se)(2)(CO)(8)(PPh3)] (2), [Os-3(mu(3)-Se)( mu(3)-CO)(CO)(7)(PPh3)(2)] (5) and [Os3(mu-OH)(2)(CO)(8)(PPh3)(2)] (6), respectively, and three known compounds, [Os-3(mu(3)-Se)(2)(CO)(9)] (1), [Os-3(mu(3)-Se)(mu-CO)(2)(CO)(7)(PPh3)] (3), and 1,2-[Os-3

Popular Abstract in Swedish Denna avhandling består av 5 fristående uppsatser i makroekonomi. Den första uppsatsen behandlar agregerad privat konsumtion. Det har nyligen föreslagits att hushållens konsumtion av icke-varaktiga varor reagerar asymmetriskt på positiva och negativa inkomstförväntningar. I denna uppsats undersöker vi huruvida detta är beroende på hur hushållens förväntningar modelleraThe first essay reexamines the proposed presence of so-called loss aversion in aggregate consumption. Recent empirical and theoretical studies have suggested, that consumption growth reacts asymmetrically to positive and negative expected income growth. After investigating the case for Swedish consumption using survey data, and a panel of annual observations on 15 OECD countries, we conclude that

Popular Abstract in Swedish Del I - "The Shift Operator on Spaces of Vector-valued Analytic Functions" består av tre artiklar som alla handlar om en viss sorts operatorer i Cowen-Douglas klassen med spektrum på enhetsskivan D, eller om man så vill, om operatorn Mz (multiplikation med z) på Hilbert rum H av vektorvärda analytiska funktioner på D. Den första artikeln, "On the Cowen-Douglas class forThis thesis consists of six articles on three different subjects in the area of complex analysis, operator theory and harmonic analysis. Part I - "The Shift Operator on Spaces of Vector-valued Analytic Functions" consists of three closely connected articles that investigate certain operators in the Cowen-Douglas class with spectrum D - the unit disc, or equivalently, the shift operator M_z

Popular Abstract in Swedish Avhandlingen behandlar barns flyttningar hemifrån i det förindustriella bondesamhället. Utöver att studera när barn lämnade hemmet kopplas också flyttningsprocessen till den förindustriella hushållsekonomins funktionssätt. Analysen görs på ett longitudinellt material för ett område i västra Skåne under perioden 1829-1866. Individerna följs från födseln, eller från det aThis study deals with the process of children leaving home and its interactions with the household economy in preindustrial society. A theoretical model of leaving home is outlined and then analyzed multivariately, using a longitudinal micro-level dataset for a sample of parishes in western Scania, Sweden, for the period 1829-1866. In a first introductory part the social and economic background as

Reactions of trans and cis isomers of the Ru-II complex [RuCl2(DMSO)(4)] with single-stranded hexanucleotide d(T(2)GGT(2)) were studied in aqueous solutions in the absence and presence of excess chloride by high performance liquid chromatography (HPLC) and matrix-assisted laser desorption/ionisation time of flight mass spectrometry (MALDI-TOF MS). Despite the different reactive species formed from

BACKGROUND: The way GPs work does not appear to be adapted to the needs of depressive patients. Therefore we wanted to examine Swedish GPs' conceptions of depressive disorders and their treatment and GPs' ideas of factors that may influence their manner of work with depressive patients. METHODS: A postal questionnaire to a stratified sample of 617 Swedish GPs. RESULTS: Most respondents assumed ant

ApoM is a novel apolipoprotein mainly present in high-density lipoprotein (HDL). It belongs to the lipocalin protein superfamily and may bind a small but so far unknown lipophilic ligand. It is secreted without cleavage of its hydrophobic signal peptide, which probably anchors apoM in the phospholipid moiety of plasma lipoproteins. Recent studies suggest that apoM may affect HDL metabolism and hav

Objectives: To compare the improvement of hip and knee osteoarthritis during treatment with naproxen. Methods: Men and women aged 40 to 75 years with symptomatic osteoarthritis of the knee or hip of at least three months' duration participated in a six week placebo controlled, double blind study with naproxen 500 mg twice daily as one treatment arm. Naproxen was given to 403 patients (280 knee, 12

This article describes and analyzes the Euro cash changeover process. The European Monetary Union, EMU, is a unique event in history, although other monetary unions were formed and existed long before. Still, this giant experiment makes it possible to study changes in the monetary environment from a unique and new position. The article tries to find factors that can help to explain the different p

Popular Abstract in Swedish Ett nytt EU-direktiv om uttjänta fordon har nyligen antagits. Direktivet kräver att från och med 2006 skall 85% av bilens vikt återvinnas och 95% från och med år 2015. Idag återvinns cirka 80%. Bildemonteringsindustrin har valts som studieobjekt i denna avhandling. De höjda återvinningskraven förväntas leda till att bildemonteringsindustrin genomgår omfattande rationaliA new EU directive on used vehicles has recently been introduced. It demands that for every scrapped car, at least 85% by weight must be recycled by the year 2006 and 95% by 2015. The current level is about 80%. The car disassembly industry was chosen as the study object of this thesis. Due to the increased demands on recycling, the disassembly industry may undergo comprehensive rationalizations a

In addition to acting as a physical barrier against microorganisms, the skin produces antimicrobial peptides and proteins. After wounding, growth factors are produced to stimulate the regeneration of tissue. The growth factor response ceases after regeneration of the tissue, when the physical barrier protecting against microbial infections is re-established. We found that the growth factors import

Background: The maintenance of postural control is fundamental for different types of physical activity. This can be measured by having subjects stand on one leg on a force plate. Many studies assessing standing balance have previously been carried out in patients with ankle ligament injuries but not in patients with ankle fractures. The aim of this study was to evaluate whether patients operated

The aim of this study was to test the hypothesis that low intensity exercise-induced low frequency fatigue is caused by failure of excitation-contraction coupling. Changes in knee extension torque at 5, 10, 15, 20 and 50 Hz electrical stimulation of quadriceps muscle in ten healthy, young, male subjects were recorded during 20-min voluntary exercise followed by 60-min recovery. In seven of the ten

The effects of five different meat raw materials used for making beefburgers on the evolution of mass transfer (total, water and fat losses), patty diameter shrinkage and porosity were studied during frying from the frozen state (-20 degrees C) to a centre temperature of 72 degrees C in a double-sided pan fryer. The normalised water losses increased linearly with increasing average temperature at

Previous cultivation may have long-lasting effects on oak forests, e.g., nitrogen (N) and carbon (C) depletion, phosphorus (P) enrichment and lowered soil acidity, which may influence soil processes, wood production and plant diversity. We used a large database on land use to sample 18 sites where oak had been planted 40-80 years ago on continuously forested land and formerly cultivated fields tha