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Phosphorus and carbon availability regulate structural composition and complexity of AM fungal mycelium.

The regulation of the structural composition and complexity of the mycelium of arbuscular mycorrhizal (AM) fungi is not well understood due to their obligate biotrophic nature. The aim of this study was to investigate the structure of extraradical mycelium at high and low availability of carbon (C) to the roots and phosphorus (P) to the fungus. We used monoxenic cultures of the AM fungus Rhizophag

Tapasin Facilitation of Natural HLA-A and -B Allomorphs Is Strongly Influenced by Peptide Length, Depends on Stability, and Separates Closely Related Allomorphs.

Despite an abundance of peptides inside a cell, only a small fraction is ultimately presented by HLA-I on the cell surface. The presented peptides have HLA-I allomorph-specific motifs and are restricted in length. So far, detailed length studies have been limited to few allomorphs. Peptide-HLA-I (pHLA-I) complexes of different allomorphs are qualitatively and quantitatively influenced by tapasin t

Assessment and analysis of housing accessibility: adapting the environmental component of the housing enabler to United States applications.

The home environment is a primary context for daily activities, especially among older adults and persons with disabilities. Functional and age-related decline can generate problems in relation to certain environmental features, necessitating modifications or other provisions of support. The determination of appropriate home interventions is best served using a person–environment (P–E) fit approac

High-Sensitivity CRP Is an Independent Risk Factor for All Fractures and Vertebral Fractures in Elderly Men: The MrOS Sweden Study

Epidemiological studies have shown low-grade inflammation measured by high-sensitivity C-reactive protein (hs-CRP) to be associated with fracture risk in women. However, it is still unclear whether hs-CRP is also associated with fracture risk in men. We therefore measured serum levels of hs-CRP in 2910 men, mean age 75 years, included in the prospective population-based MrOS Sweden cohort. Study p

Evaluation of Plasma A beta as Predictor of Alzheimer's Disease in Older Individuals Without Dementia: A Population-Based Study

Amyloid-beta (A beta) pathology is a major component in the mechanisms behind Alzheimer's disease (AD). Measurement of A beta(42) in cerebrospinal fluid predicts cognitive decline in patients with mild cognitive impairment and identifies AD in patients with dementia. However, studies on A beta in plasma are contradictory. In this prospective population-based study, plasma A beta(42) and A beta(40)

(3Z,6Z,9Z,12Z,15Z)-pentacosapentaene and (9Z,11E)-tetradecadienyl acetate: sex pheromone of the spruce coneworm Dioryctria abietella (Lepidoptera: Pyralidae)

The spruce coneworm, Dioryctria abietella Denis & Schiffermüller (Lepidoptera: Pyralidae), is a major pest in spruce seed orchards in Europe. Initial work on its pheromone ecology reported significant attraction of males to (9Z,11E)-tetradecadienyl acetate (9Z,11E-14:OAc), but this compound appeared to be a very weak attractant in field trials. In this study, we show that a second female-produ

Fracture characterisation of green glued-polyurethane adhesive bonds in Mode I

Unseasoned (green) spruce timber side boards of size 25 × 120 × 600 mm were flatwise-glued with a one-component PUR adhesive. Glued pairs of boards were then kiln-dried to 12 % moisture content. A special small-scale specimen for testing the fracture properties of the adhesive bond in Mode I was developed in order to evaluate the adhesive bond properties. The complete force versus deformation curv

Meta-analysis of Dense Genecentric Association Studies Reveals Common and Uncommon Variants Associated with Height

Height is a classic complex trait with common variants in a growing list of genes known to contribute to the phenotype. Using a genecentric genotyping array targeted toward cardiovascular-related loci, comprising 49,320 SNPs across approximately 2000 loci, we evaluated the association of common and uncommon SNPs with adult height in 114,223 individuals from 47 studies and six ethnicities. A total

Numerical predictions of augmented heat transfer of an internal blade tip-wall by hemispherical dimples

The heat transferred to the turbine blade is substantially increased as the turbine inlet temperature is increased. Improved cooling methods are therefore needed for the turbine blades to ensure a long durability and safe operation. The blade tip region is exposed to very hot gas flow, and suffers high local thermal loads due to the external tip leakage flow. A common way to cool the tip is to des

Faceting of Rhodium(553) in Realistic Reaction Mixtures of Carbon Monoxide and Oxygen

We have investigated the gas composition-dependent faceting of a Rh(553) surface during catalytic CO oxidation under semirealistic reaction conditions using surface X-ray diffraction. We find that under stoichiometric CO and O-2 conditions, the Rh(553) surface maintains its surface orientation without facet formation. In oxygen excess, the CO oxidation reaction becomes mass-transfer limited by the

A new paradigm for primary prevention strategy in people with elevated risk of stroke

Existing methods of primary stroke prevention are not sufficiently effective. Based on the recently developed Stroke Riskometer app, a new mass-elevated risk stroke/cardiovascular disease prevention' approach as an addition to the currently adopted absolute risk stroke/cardiovascular disease prevention approach is being advocated. We believe this approach is far more appealing to the individuals c

Reduced insular gamma-aminobutyric acid in fibromyalgia

Objective Recent scientific findings have reinvigorated interest in examining the role of gamma-aminobutyric acid (GABA), the major inhibitory central nervous system neurotransmitter, in chronic pain conditions. Decreased inhibitory neurotransmission is a proposed mechanism in the pathophysiology of chronic pain syndromes such as fibromyalgia (FM). The purpose of this study was to test the hypothe

The mouse QTL map helps interpret human genome-wide association studies for HDL cholesterol

Genome-wide association (GWA) studies represent a powerful strategy for identifying susceptibility genes for complex diseases in human populations but results must be confirmed and replicated. Because of the close homology between mouse and human genomes, the mouse can be used to add evidence to genes suggested by human studies. We used the mouse quantitative trait loci (QTL) map to interpret resu

Multi-scale characterization of pasta during cooking using microscopy and real-time magnetic resonance imaging

Macroscopic properties of pasta, such as the texture, are formed during cooking by a complex interplay of water and heat with the structuring agents starch and gluten. The impact of the starch-to-gluten ratio on microstructure and water distribution in pasta was analyzed by a multi-scale approach combining magnetic resonance imaging (MRI) and light microscopy. The cooking process and thus the wate

A note on random coverings of tori

This note provides a generalization of a recent result by Jarvenpaa, Jarvenpaa, Koivusalo, Li, and Suomala (to appear) on the dimension of limsup-sets of random coverings of tori. The result in this note is stronger in the sense that it provides also a large intersection property of the limsup-sets, the assumptions are weaker, and it implies the result of Jarvenpaa, Jarvenpaa, Koivusalo, Li, and S

Nonlinear Model Predictive Control of a CO2 Post-Combustion Absorption Unit

A dynamic model of a chemical CO2 absorption process with aqueous monoethanolamine (MEA) is presented, validated against experimental data. Based on the validated model, a reduced-order model is developed, suitable for an online optimization control strategy. The objective of the optimization is to enable fast adap- tations to changes in operating conditions of the power plant, while minimizing th

Political participation in an age of mediatisation : toward a new research agenda

The media landscape and its societal significance is in rapid transition; likewise basic features of democracy are changing. In this article we pursue these two strands in order to sketch the background to a need for a new research agenda, as well as to arrive at proposals regarding the directions that such research can take. In regard to democracy our emphasis is on the dimension of participation