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CONTEXT: Whether multisystem morbidity in Cushing's disease (CD) remains elevated during long-term remission is still undetermined. OBJECTIVE: To investigate comorbidities in patients with CD. DESIGN, SETTING, AND PATIENTS: A retrospective, nationwide study of patients with CD identified in the Swedish National Patient Register between 1987 and 2013. Individual medical records were reviewed to ver

We investigate the angle-resolved photoelectron spectra from laser-Assisted photoionization for helium and neon atoms using an ab initio method based on time-dependent surface flux and configuration interaction singles. We find that the shape of the distributions can be interpreted using a propensity rule, an intrinsic difference in the absorption and the emission processes, as well as interferenc

We present calculations on the atomic delay in photoionzation obtained with different combinations of linearly and circularly polarized light, and show how a tensor operator approach can be used to readily obtain results for any combination from a single calculation of the radial integrals. We find that for certain choices of polarization and detection geometry a single time-delay measurement is e

Background: Women who deliver pre-term have been reported to have increased future risks of cardiometabolic disorders. However, their long-term risks of ischemic heart disease (IHD) and whether such risks are due to shared familial factors are unclear. A better understanding of these risks may help improve long-term clinical follow-up and interventions to prevent IHD in women. Objectives: The purp

In a pioneering study in New England Journal of Medicine, Schweitzer et al. (2020) report on a patient with Parkinson's disease who received a graft of dopamine neurons obtained from in vitro differentiated induced pluripotent stem cells, derived from the patient's own skin fibroblasts, showing the feasibility of autologous transplantation for dopamine cell replacement.

OBJECTIVE: The aim of this study was to investigate if there is a causal relationship between circulating levels of TIM-1 (T-cell immunoglobulin and mucin domain 1) and incidence of stroke. Approach and Results: Plasma TIM-1 was analyzed in 4591 subjects (40% men; mean age, 57.5 years) attending the Malmö Diet and Cancer Study. Incidence of stroke was studied in relation to TIM-1 levels during a m

An array antenna design based on a gridded parasitic patch stacked microstrip antenna element is presented. The radiating part in the top layer of one antenna element has nine rectangular metal patches placed in a grid with three rows and three columns with a separation of 0.1 mm between the patches. Two means of realising the array are investigated. In a regular 2 × 2 concept, the parasitic patch

The convergence of advances in medical science, human biology, data science, and technology has enabled the generation of new insights into the phenotype known as "diabetes." Increased knowledge of this condition has emerged from populations around the world, illuminating the differences in how diabetes presents, its variable prevalence, and how best practice in treatment varies between population

Blickens kreativitet står i fokus i doktorsavhandlingen Pippi mellan världar (2020). Här introducerar jag nymaterialistiska tankegångar i en bildretorisk studie. Jag betonar särskilt lyssnarens/betraktarens egen medskapande roll när hon kreativt orienterar sig i sin omvärld. Med exempel hämtade ur svenska och tyska bokutgåvor visar jag hur bokillustrationer och pärmbilder framhäver det lekfullt no

We present a useful methodology to simulate ionic fluids confined by two charged and perfectly conducting surfaces. Electrostatic interactions are treated using a modified 3D Ewald sum, which accounts for all image charges across the conductors, as well as the 2D periodicity, parallel to the surfaces. The energy expression is exact, and the method is trivial to implement in existing Ewald codes. W

As one of the successful approaches to GaAs surface passivation, wet-chemical nitridation is applied here to relate the effect of surface passivation to carrier recombination processes in bulk GaAs. By combining time-resolved photoluminescence and optical pump-THz probe measurements, we found that surface hole trapping dominates the decay of photoluminescence, while photoconductivity dynamics is l

Anisotropic macromolecules exposed to non-equilibrium (active) noise are very common in biological systems, and an accurate understanding of their anisotropic dynamics is therefore crucial. Here, we experimentally investigate the dynamics of isolated chains assembled from magnetic microparticles at a liquid-air interface and moving in an active bath consisting of motile E. coli bacteria. We invest

For patients hospitalized with severe influenza A virus infection, morbidity and mortality remain high. MHAA4549A, a human monoclonal antibody targeting the influenza A virus hemagglutinin stalk, has demonstrated pharmacological activity in animal studies and in a human influenza A challenge study. We evaluated the safety and efficacy of MHAA4549A plus oseltamivir against influenza A virus infecti

We consider the problem of distributed decision making in a quadratic game between a team of players and nature. Each player has limited information that could be different from the other players in the team. We show that if there is a solution to the minimax team problem, then the linear policies are optimal, and we show how to find the linear optimal solution by solving a linear matrix inequalit

In this paper we analyze how sampling instant error affects the receiver performance in raised-cosine filtered DS-CDMA systems. An expression is presented for the Signal to Inter Chip Interference (S/ICI) ratio as a function of the sampling error characteristics and Raised-cosine roll-off factor. Finally, we use the analysis in the paper to derive sufficient sampling resolution for the high perfor

An H∞ control system is considered with the constraint that process disturbances and measurement noise cannot both be large. It is unnatural to couple process disturbance and measurement noise in this way. It is better to assume that some signals are stochastic. Explicit formulas for the value of the game are determined.

A simple second order feed-forward disturbance attenuation problem is analyzed. The problem has one free parameter, the control weight ρ in the loss function. It is found that controller structure and uniqueness for H∞ - control, in the optimal case, changes when ρ is varied. Sensitivity to initial conditions is also drastically changed. The example is simple enough to allow a solution by formula