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A family perspective : how this product can inform and empower families of youth with spina bifida

This article focuses on how the Life Course Model Web site can help family members build on the strengths of individuals with spina bifida and address areas of difficulty. A developmental perspective is adopted, which maintains that the Life Course Model Web site is useful at all stages of development, with the information provided for families at one stage of development building on the informati

The National Spina Bifida Program transition initiative : the people, the plan, and the process

This article outlines and summarizes the rationale and the working process that was undertaken by the National Spina Bifida Program to address the issues of transitioning throughout the life course for persons growing up with spina bifida. Their challenges include achieving independent living, vocational independence, community mobility, and participation in social activities, and health managemen

A deviational approach to blockmodeling of valued networks

This article proposes a novel approach to blockmodeling of valued (one-mode) networks where the identification of (binary) block patterns in the valued relations differ from existing approaches. Rather than looking at the absolute values of relations, or examining valued ties on a per-actor basis (cf. Nordlund, 2007), the approach identifies prominent (binary) ties on the basis of deviations from

Low Complexity Adaptive Channel Estimation and QR Decomposition for an LTE-A Downlink

This paper presents a link adaptive processor to perform low-complexity channel estimation and QR decomposition (QRD) in Long Term Evolution-Advanced (LTE-A) receivers. The processor utilizes frequency domain correlation of the propagation channel to adaptively avoid unnecessary computations in the received signal processing, achieving significant complexity reduction with negligible performance l

International trade in fuel commodities : A network approach

Much as the contemporary understanding of world trade is often based on simple models where two countries engage in trade, so is world trade in fuel commodities typically conceived as consisting of either net-importing or net-exporting countries. However, by paying attention to the structure of world trade, represented by actually occurring trade flows between the actors in such networks, it becom

Performance Assessment of Wastewater Treatment Plants : Multi-Objective Analysis Using Plant-Wide Models

As the knowledge about anthropogenic impacts of climate change has grown, the awareness of the contributions from treatment of wastewater has widened the scope for wastewater treatment plants (WWTPs). Not only shall ever stricter effluent constraints be met, but also energy efficiency be increased, greenhouse gases mitigated and resources recovered. All under a constant pressure on costs. The main

Parents' Lived Experiences During Their Children's Radiotherapy

BACKGROUND: The aim of radiotherapy is to provide a cure and/or symptomatic relief for children with cancer. Treatment is delivered on a daily basis, 5 days per week, over the course of 5 to 35 days. Many parents find that leaving their children alone during treatment and exposing them to radiation is a challenging experience. To gain an understanding of parents' lived experiences, 10 parents were

Caregiver-reported antiretroviral therapy non-adherence during the first week and after a month of treatment initiation among children diagnosed with HIV in Ethiopia

To achieve optimal virologic suppression for children undergoing antiretroviral therapy (ART), adherence must be excellent. This is defined as taking more than 95% of their prescribed doses. To our knowledge, no study in Ethiopia has evaluated the level of treatment adherence at the beginning of the child's treatment. Our aim was therefore to evaluate caregiver-reported ART non-adherence among chi

Staphylococcus aureus toxins - Influence on food safety and animal health

Staphylococcus aureus (S. aureus) is a notorious opportunistic foodborne pathogen and also a common cause of bovine mastitis. It is known to produce many different virulence factors, including various staphylococcal enterotoxins and toxic shock syndrome toxin-1 (TSST-1). The aim of this work was to investigate the regulation, expression, formation and role of S. aureus toxins in relation to food s

Accuracy of GFR estimating equations in a large Swedish cohort : implications for radiologists in daily routine and research

BACKGROUND: Guidelines recommend estimation of glomerular filtration rate (eGFR) prior to iodine contrast media (CM) examinations. It is also recommended that absolute eGFR in mL/min, not commonly used relative GFR (adjusted to body surface area; mL/min/1.73 m(2)), should be preferred when dosing and evaluating toxicity of renally excreted drugs.PURPOSE: To validate the absolute Lund-Malmö equatio

Production of Cystatin C Wild Type and Stabilized Mutants

Cystatin C is produced in all nucleated cells. It has various functions and biological activities. Researchers are focused on its role in kidney diseases as a marker of glomerular filtration but also as a very important link in development of amyloid diseases. This work describes expression and purification of both wild type (wt) and stabilized form (stab 1 and 2) of wt cystatin C and amyloid-form

The dispersion of water proton spin-lattice relaxation rates in aqueous human protein HC (alpha1-microglobulin) solutions

The (1)H NMR Fast Field Cycling relaxometry was applied to study the molecular dynamics of the human protein HC (alpha (1)-microglobulin), its hydration and aggregation in solution state. The (1)H NMRD data have revealed the complex nature of the water/protein HC system resulting from the co-existence of monomer and dimer forms of the protein in solution as well as the presence of oligosaccharides