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Glial cell line-derived neurotrophic factor (GDNF) exhibits potent effects on survival and function of midbrain dopaminergic (DA) neurons in a variety of models. Although other growth factors expressed in the vicinity of developing DA neurons have been reported to support survival of DA neurons in vitro, to date none of these factors duplicate the potent and selective actions of GDNF in vivo. We r
The steam pressure control loops in the drying section of a paper machine play an important role for the quality of the moisture content control. The steam pressure loops are essential for the effective use of advanced control schemes for the moisture control. From mathematical model building and experiments on industrial paper machines it is found that the dynamics from the steam valves to the st
AIM: To determine the involvement of extracellular signal-regulated kinase 1/2 (ERK1/2) pathway in the expression of endothelin receptor type B (ETB) during culture. METHODS: SB386023, a specific inhibitor for ERK1/2 pathway, was used to define the intracellular signaling pathway for the upregulation of ETB receptors and sarafotoxin 6c (S6c), a selective agonist for ETB receptors, induced contract
Essä om förnyelsen av James Bond-serien på 1990-talet
Tuberculosis of the pancreas is very rare and can present with many signs and symptoms, including obstructive jaundice, weight loss and a mass in the head of the pancreas. Hence the diagnosis of pancreatic tuberculosis remains a challenge and a high index of suspicion is required. If a turnout is suspected then an ultrasound- or CT-guided fine needle aspiration should be performed. Even if the ini
Formation of calcium oxalate incrusts, scaling, may cause severe problems in the pulp and paper industry. Enzymatic degradation of oxalic acid provides a novel approach to eliminate the problems with calcium oxalate precipitation. The performance of two oxalate-degrading enzymes, oxalate oxidase from barley and oxalate decarboxylase from Aspergillus, was tested in model experiments with respect to
This paper shows how culture is used and transformed as it becomes mobilized as a strategic resource in a regional development project within a neoliberal economic discourse. The focus is how four smaller municipalities in the transnational Swedish/Danish Öresund region initiate a process of cultural mappings in order to incorporate local culture and cultural heritage in the regional tourist econo
Om jazzinspelningar på Thomas Alva Edisons skivbolag under 1920-talet.
1. Mechanical transients in fibre bundles of skinned smooth muscle of guinea-pig taenia coli at 21-22 degrees C were investigated by recording tension responses to length changes of up to 9%, complete within 0.3 ms. 2. The length-force relationship, recorded continuously during rapid stretch of a Ca(2+)-activated contracted muscle, was linear up to at least 2.5 times the isometric force, correspon
The nuclear receptor peroxisome proliferator-activated receptor delta [PPARdelta/beta (NR1C2)] has been implicated in colorectal carcinogenesis by various molecular genetic observations. These observations have recently been supported by studies of activation of PPARdelta by pharmacological agents. Here we present the first report of the stimulation of breast and prostate cancer cell growth using
The study of quark jets in e(+)e(-) reactions at LEP has demonstrated that the hadronisation process is reproduced well by the Lund string model. However. our understanding of gluon fragmentation is less complete. In this study enriched quark and gluon jet samples of different purities are selected in three-jet events from hadronic decays of the Z collected by the DELPHI experiment in the LEP runs
